U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RUNX2 RUNX family transcription factor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703331, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RUNX2provided by VGNC
    Official Full Name
    RUNX family transcription factor 2provided by VGNC
    Primary source
    VGNC:VGNC:76947
    See related
    Ensembl:ENSMMUG00000019819
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RUNX2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (123698710..124050672, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (46509571..46638470)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114677600 Neighboring gene uncharacterized LOC114677601 Neighboring gene chloride intracellular channel 5 Neighboring gene U6 spliceosomal RNA Neighboring gene SPT3 homolog, SAGA and STAGA complex component Neighboring gene pre-mRNA-splicing factor RBM22-like Neighboring gene microRNA mir-586

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hemopoiesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    runt-related transcription factor 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      123698710..124050672 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028847502.1 → XP_028703335.1  runt-related transcription factor 2 isoform X5

      UniProtKB/TrEMBL
      A0A5F8A0E8
      Related
      ENSMMUP00000070378.1, ENSMMUT00000103682.1
      Conserved Domains (1) summary
      pfam00853
      Location:109 → 230
      Runt; Runt domain

    2. XM_028847501.1 → XP_028703334.1  runt-related transcription factor 2 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A0E8
      Conserved Domains (1) summary
      pfam00853
      Location:177 → 298
      Runt; Runt domain

    3. XM_028847499.1 → XP_028703332.1  runt-related transcription factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QRV2, A0A5F8A0E8
      Related
      ENSMMUP00000050780.2, ENSMMUT00000070953.2
      Conserved Domains (1) summary
      pfam00853
      Location:177 → 298
      Runt; Runt domain

    4. XM_028847500.1 → XP_028703333.1  runt-related transcription factor 2 isoform X3

      UniProtKB/TrEMBL
      F7FY42
      Related
      ENSMMUP00000026057.4, ENSMMUT00000027852.4
      Conserved Domains (3) summary
      pfam05109
      Location:334 → 522
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00853
      Location:177 → 298
      Runt; Runt domain
      pfam08504
      Location:476 → 567
      RunxI; Runx inhibition domain

    5. XM_001100961.3 → XP_001100961.2  runt-related transcription factor 2 isoform X2

      UniProtKB/TrEMBL
      F7FY47
      Related
      ENSMMUP00000026056.4, ENSMMUT00000027851.4
      Conserved Domains (3) summary
      pfam05109
      Location:334 → 544
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00853
      Location:177 → 298
      Runt; Runt domain
      pfam08504
      Location:498 → 589
      RunxI; Runx inhibition domain

    6. XM_015136486.2 → XP_014991972.2  runt-related transcription factor 2 isoform X6

      Conserved Domains (2) summary
      pfam00853
      Location:95 → 216
      Runt; Runt domain
      pfam08504
      Location:358 → 449
      RunxI; Runx inhibition domain

    7. XM_015136487.2 → XP_014991973.2  runt-related transcription factor 2 isoform X7

      Conserved Domains (1) summary
      pfam00853
      Location:177 → 298
      Runt; Runt domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.