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    RTKN rhotekin [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708722, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RTKNprovided by VGNC
    Official Full Name
    rhotekinprovided by VGNC
    Primary source
    VGNC:VGNC:76943
    Locus tag
    EGK_05467
    See related
    Ensembl:ENSMMUG00000002721
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RTKN in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (34374744..34391368)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (75443799..75460240, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene WW domain binding protein 1 Neighboring gene INO80 complex subunit B Neighboring gene WD repeat domain 54 Neighboring gene chromosome 13 C2orf81 homolog Neighboring gene high mobility group protein HMG-I/HMG-Y-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in actomyosin contractile ring assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in septin ring organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actomyosin contractile ring IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rhotekin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261179.1 → NP_001248108.1  rhotekin

      See identical proteins and their annotated locations for NP_001248108.1

      Status: PROVISIONAL

      Source sequence(s)
      JU322391
      UniProtKB/TrEMBL
      A0A5F8AST9, A0A8J8XUI4, F7HMS1, G7NAE1
      Related
      ENSMMUP00000003661.2, ENSMMUT00000003874.4
      Conserved Domains (3) summary
      smart00742
      Location:37 → 91
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:309 → 419
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:117 → 270
      Anillin; Cell division protein anillin

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      34374744..34391368
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015112543.2 → XP_014968029.1  rhotekin isoform X8

      UniProtKB/TrEMBL
      A0A5F8AST9
      Conserved Domains (4) summary
      smart00742
      Location:37 → 91
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:309 → 419
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam00169
      Location:313 → 411
      PH; PH domain
      pfam08174
      Location:117 → 270
      Anillin; Cell division protein anillin

    2. XM_028831560.1 → XP_028687393.1  rhotekin isoform X11

      UniProtKB/TrEMBL
      A0A5F8AST9
      Conserved Domains (3) summary
      smart00742
      Location:37 → 91
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:309 → 419
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:117 → 267
      Anillin; Cell division protein anillin

    3. XM_015112540.2 → XP_014968026.1  rhotekin isoform X4

      UniProtKB/TrEMBL
      A0A5F8AST9
      Conserved Domains (4) summary
      smart00742
      Location:37 → 91
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      pfam00169
      Location:320 → 384
      PH; PH domain
      pfam08174
      Location:117 → 270
      Anillin; Cell division protein anillin
      cl17171
      Location:297 → 392
      PH-like; Pleckstrin homology-like domain

    4. XM_028831556.1 → XP_028687389.1  rhotekin isoform X7

      UniProtKB/TrEMBL
      A0A5F8AST9
      Conserved Domains (3) summary
      smart00742
      Location:37 → 91
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:239 → 349
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:117 → 176
      Anillin; Cell division protein anillin

    5. XM_028831552.1 → XP_028687385.1  rhotekin isoform X1

      UniProtKB/TrEMBL
      A0A5F8AST9, A0A8J8XUI4, F7HMS1, G7NAE1
      Conserved Domains (3) summary
      smart00742
      Location:37 → 91
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:309 → 419
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:117 → 270
      Anillin; Cell division protein anillin

    6. XM_015112539.2 → XP_014968025.1  rhotekin isoform X2

      UniProtKB/TrEMBL
      H9EQW2, I0FGM1
      Related
      ENSMMUP00000066849.1, ENSMMUT00000104921.1
      Conserved Domains (3) summary
      smart00742
      Location:23 → 78
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:296 → 406
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:104 → 257
      Anillin; Cell division protein anillin

    7. XM_028831558.1 → XP_028687391.1  rhotekin isoform X9

      UniProtKB/TrEMBL
      I0FGM1
      Conserved Domains (3) summary
      smart00742
      Location:23 → 78
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:226 → 336
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:104 → 163
      Anillin; Cell division protein anillin

    8. XM_028831555.1 → XP_028687388.1  rhotekin isoform X5

      UniProtKB/TrEMBL
      F7HKW7, I0FGM1
      Conserved Domains (3) summary
      smart00742
      Location:23 → 78
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      pfam08174
      Location:104 → 254
      Anillin; Cell division protein anillin
      cl17171
      Location:284 → 379
      PH-like; Pleckstrin homology-like domain

    9. XM_028831559.1 → XP_028687392.1  rhotekin isoform X10

      UniProtKB/TrEMBL
      I0FGM1
      Conserved Domains (3) summary
      smart00742
      Location:23 → 78
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:296 → 406
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:104 → 254
      Anillin; Cell division protein anillin

    10. XM_028831554.1 → XP_028687387.1  rhotekin isoform X5

      UniProtKB/TrEMBL
      F7HKW7, I0FGM1
      Related
      ENSMMUP00000003665.3, ENSMMUT00000003878.4
      Conserved Domains (3) summary
      smart00742
      Location:23 → 78
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      pfam08174
      Location:104 → 254
      Anillin; Cell division protein anillin
      cl17171
      Location:284 → 379
      PH-like; Pleckstrin homology-like domain

    11. XM_015112541.2 → XP_014968027.1  rhotekin isoform X6

      UniProtKB/TrEMBL
      I0FGM1
      Conserved Domains (3) summary
      cd13249
      Location:259 → 369
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:67 → 220
      Anillin; Cell division protein anillin
      cl00087
      Location:1 → 41
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    12. XM_015112538.2 → XP_014968024.1  rhotekin isoform X2

      UniProtKB/TrEMBL
      H9EQW2, I0FGM1
      Conserved Domains (3) summary
      smart00742
      Location:23 → 78
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:296 → 406
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:104 → 257
      Anillin; Cell division protein anillin

    13. XM_028831557.1 → XP_028687390.1  rhotekin isoform X9

      UniProtKB/TrEMBL
      I0FGM1
      Conserved Domains (3) summary
      smart00742
      Location:23 → 78
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:226 → 336
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:104 → 163
      Anillin; Cell division protein anillin

    14. XM_028831553.1 → XP_028687386.1  rhotekin isoform X3

      UniProtKB/TrEMBL
      I0FGM1
      Related
      ENSMMUP00000079955.1, ENSMMUT00000084528.1
      Conserved Domains (3) summary
      smart00742
      Location:12 → 65
      Hr1; Rho effector or protein kinase C-related kinase homology region 1 homologues
      cd13249
      Location:283 → 393
      PH_rhotekin2; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:91 → 244
      Anillin; Cell division protein anillin
    Nucleotide Protein
    Heading Accession and Version

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