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    ZNF532 zinc finger protein 532 [ Homo sapiens (human) ]

    Gene ID: 55205, updated on 27-Nov-2024

    Summary

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    Official Symbol
    ZNF532provided by HGNC
    Official Full Name
    zinc finger protein 532provided by HGNC
    Primary source
    HGNC:HGNC:30940
    See related
    Ensembl:ENSG00000074657 MIM:619066; AllianceGenome:HGNC:30940
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in endometrium (RPKM 20.9), prostate (RPKM 17.9) and 22 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ZNF532 in Genome Data Viewer
    Location:
    18q21.32
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (58862924..58986480)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (59064004..59187774)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (56530156..56653712)

    Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs1397 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56475059-56476049 Neighboring gene U8 small nucleolar RNA Neighboring gene RNA, U6 small nuclear 219, pseudogene Neighboring gene long intergenic non-protein coding RNA 1926 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56513039-56513851 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56513852-56514664 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56514665-56515477 Neighboring gene Sharpr-MPRA regulatory region 466 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:56529025-56529566 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56529567-56530106 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56537205-56538186 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:56556548-56557048 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:56557049-56557549 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr18:56559638-56560464 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56582766-56583276 Neighboring gene RNA, U2 small nuclear 69, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:56635193-56636106 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr18:56650842-56652041 Neighboring gene O-acyltransferase like, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9489 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56716067-56717037 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56717038-56718007 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr18:56729547-56730746 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13406 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13407 Neighboring gene NANOG hESC enhancer GRCh37_chr18:56758336-56758837 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9490 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13408 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13409 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9491 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13410 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13411 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13412 Neighboring gene SEC11 homolog C, signal peptidase complex subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma. Alekseyenko AA, et al. Proc Natl Acad Sci U S A, 2017 May 23. PMID 28484033, Free PMC Article
    2. Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532. Fan L, et al. Bioengineered, 2022 Feb. PMID 35112956, Free PMC Article
    3. NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion. Chen M, et al. Virchows Arch, 2022 Apr. PMID 35064291
    4. circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD. Fu XL, et al. Endocr J, 2024 Jul 12. PMID 38811189
    5. CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis. Liang GH, et al. J Diabetes Investig, 2022 May. PMID 34839589, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD.
      Title: circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD.
    2. CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis.
      Title: CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis.
    3. NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion.
      Title: NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion.
    4. Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
      Title: Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
    5. The authors discovered ZNF532 associated with BRD4-NUT in NMC patient cells. ChIP sequencing revealed the formation of ZNF532-NUT-associated hyperacetylated megadomains, distinctly localized but otherwise analogous to those found in BRD4-NUT patient cells.
      Title: Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.
    6. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ10697

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 532

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001318726.2 → NP_001305655.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-9 all encode the same isoform (a).
      Source sequence(s)
      AA807005, AK001559, AK128058, BC130618, DB299524
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Related
      ENSP00000468532.1, ENST00000591083.5
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    2. NM_001318727.2 → NP_001305656.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-9 all encode the same isoform (a).
      Source sequence(s)
      AA807005, AB046849, AC090233, AK001559, DA108216, DB299524
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Related
      ENSP00000466007.1, ENST00000589288.5
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    3. NM_001318728.2 → NP_001305657.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-9 all encode the same isoform (a).
      Source sequence(s)
      AA807005, AK001559, BC036366, DA191371, DB299524
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Related
      ENSP00000465709.1, ENST00000591230.5
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    4. NM_001353525.2 → NP_001340454.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 1-4 and 6-9, encodes isoform a.
      Source sequence(s)
      AC040963, AC090233
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    5. NM_001353526.2 → NP_001340455.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variants 1-5 and 7-9, encodes isoform a.
      Source sequence(s)
      AC040963, AC090233
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    6. NM_001353527.2 → NP_001340456.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 1-6, 8, and 9, encodes isoform a.
      Source sequence(s)
      AC040963, AC090233
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    7. NM_001353528.2 → NP_001340457.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variants 1-7 and 9, encodes isoform a.
      Source sequence(s)
      AC040963, AC090233
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    8. NM_001353529.2 → NP_001340458.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9), as well as variants 1-8, encodes isoform a.
      Source sequence(s)
      AC040963, AC090233
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    9. NM_001353530.2 → NP_001340459.1  zinc finger protein 532 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10), as well as variants 11 and 12, encodes isoform b.
      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (2) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam16622
      Location:1195 → 1223
      zf-C2H2_11; zinc-finger C2H2-type

    10. NM_001353531.2 → NP_001340460.1  zinc finger protein 532 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11), as well as variants 10 and 12, encodes isoform b.
      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (2) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam16622
      Location:1195 → 1223
      zf-C2H2_11; zinc-finger C2H2-type

    11. NM_001353532.2 → NP_001340461.1  zinc finger protein 532 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12), as well as variants 10 and 11, encodes isoform b.
      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (2) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam16622
      Location:1195 → 1223
      zf-C2H2_11; zinc-finger C2H2-type

    12. NM_001353533.2 → NP_001340462.1  zinc finger protein 532 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (3) summary
      sd00017
      Location:968 → 988
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13912
      Location:1206 → 1227
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1142 → 1168
      zf-C2H2_11; zinc-finger C2H2-type

    13. NM_001353534.2 → NP_001340463.1  zinc finger protein 532 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (2) summary
      sd00017
      Location:968 → 988
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam16622
      Location:1136 → 1164
      zf-C2H2_11; zinc-finger C2H2-type

    14. NM_001353535.2 → NP_001340464.1  zinc finger protein 532 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15), as well as variant 16, encodes isoform e.
      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (3) summary
      sd00017
      Location:853 → 873
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13912
      Location:1090 → 1112
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1025 → 1053
      zf-C2H2_11; zinc-finger C2H2-type

    15. NM_001353536.2 → NP_001340465.1  zinc finger protein 532 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (16), as well as variant 15, encodes isoform e.
      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (3) summary
      sd00017
      Location:853 → 873
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13912
      Location:1090 → 1112
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1025 → 1053
      zf-C2H2_11; zinc-finger C2H2-type

    16. NM_001353537.2 → NP_001340466.1  zinc finger protein 532 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (3) summary
      sd00017
      Location:853 → 873
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13912
      Location:1086 → 1108
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1021 → 1049
      zf-C2H2_11; zinc-finger C2H2-type

    17. NM_001353538.2 → NP_001340467.1  zinc finger protein 532 isoform g

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233
      Conserved Domains (3) summary
      sd00017
      Location:756 → 778
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13912
      Location:996 → 1018
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:931 → 959
      zf-C2H2_11; zinc-finger C2H2-type

    18. NM_001375912.1 → NP_001362841.1  zinc finger protein 532 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Related
      ENSP00000468238.1, ENST00000591808.6
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    19. NM_001375913.1 → NP_001362842.1  zinc finger protein 532 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (3) summary
      sd00017
      Location:968 → 988
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13912
      Location:1206 → 1227
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1142 → 1168
      zf-C2H2_11; zinc-finger C2H2-type

    20. NM_018181.6 → NP_060651.2  zinc finger protein 532 isoform a

      See identical proteins and their annotated locations for NP_060651.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1-9 all encode the same isoform (a).
      Source sequence(s)
      AA807005, AF295077, AK128058, BE219488, BF591635
      Consensus CDS
      CCDS11969.1
      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Related
      ENSP00000338217.4, ENST00000336078.8
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    RNA

    1. NR_148459.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233

    2. NR_148460.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC040963, AC090233

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

      Range
      58862924..58986480
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047437584.1 → XP_047293540.1  zinc finger protein 532 isoform X3

    2. XM_047437592.1 → XP_047293548.1  zinc finger protein 532 isoform X4

    3. XM_047437606.1 → XP_047293562.1  zinc finger protein 532 isoform X15

    4. XM_047437607.1 → XP_047293563.1  zinc finger protein 532 isoform X16

    5. XM_047437599.1 → XP_047293555.1  zinc finger protein 532 isoform X6

    6. XM_017025810.2 → XP_016881299.1  zinc finger protein 532 isoform X2

      UniProtKB/TrEMBL
      B3KXW2

    7. XM_047437588.1 → XP_047293544.1  zinc finger protein 532 isoform X3

    8. XM_047437593.1 → XP_047293549.1  zinc finger protein 532 isoform X4

    9. XM_047437598.1 → XP_047293554.1  zinc finger protein 532 isoform X5

    10. XM_017025815.2 → XP_016881304.1  zinc finger protein 532 isoform X7

      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
      UniProtKB/TrEMBL
      B3KXW2
      Conserved Domains (4) summary
      sd00017
      Location:1027 → 1047
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02591
      Location:784 → 819
      zf-RING_7; C4-type zinc ribbon domain
      pfam13912
      Location:1265 → 1286
      zf-C2H2_6; C2H2-type zinc finger
      pfam16622
      Location:1199 → 1227
      zf-C2H2_11; zinc-finger C2H2-type

    11. XM_047437603.1 → XP_047293559.1  zinc finger protein 532 isoform X11

    12. XM_047437608.1 → XP_047293564.1  zinc finger protein 532 isoform X17

    13. XM_047437591.1 → XP_047293547.1  zinc finger protein 532 isoform X4

    14. XM_047437605.1 → XP_047293561.1  zinc finger protein 532 isoform X15

    15. XM_047437596.1 → XP_047293552.1  zinc finger protein 532 isoform X5

    16. XM_047437581.1 → XP_047293537.1  zinc finger protein 532 isoform X2

    17. XM_047437586.1 → XP_047293542.1  zinc finger protein 532 isoform X3

    18. XM_047437600.1 → XP_047293556.1  zinc finger protein 532 isoform X7

      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6

    19. XM_047437582.1 → XP_047293538.1  zinc finger protein 532 isoform X3

    20. XM_047437589.1 → XP_047293545.1  zinc finger protein 532 isoform X3

    21. XM_047437585.1 → XP_047293541.1  zinc finger protein 532 isoform X3

    22. XM_047437587.1 → XP_047293543.1  zinc finger protein 532 isoform X3

    23. XM_047437594.1 → XP_047293550.1  zinc finger protein 532 isoform X4

    24. XM_017025811.3 → XP_016881300.1  zinc finger protein 532 isoform X3

      UniProtKB/TrEMBL
      B3KXW2

    25. XM_047437590.1 → XP_047293546.1  zinc finger protein 532 isoform X4

    26. XM_047437595.1 → XP_047293551.1  zinc finger protein 532 isoform X5

    27. XM_047437583.1 → XP_047293539.1  zinc finger protein 532 isoform X3

    28. XM_047437597.1 → XP_047293553.1  zinc finger protein 532 isoform X5

    29. XM_047437601.1 → XP_047293557.1  zinc finger protein 532 isoform X7

      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6

    30. XM_047437609.1 → XP_047293565.1  zinc finger protein 532 isoform X19

    31. XM_017025830.2 → XP_016881319.1  zinc finger protein 532 isoform X14

    32. XM_017025824.2 → XP_016881313.1  zinc finger protein 532 isoform X9

      UniProtKB/TrEMBL
      B3KXW2

    33. XM_017025823.2 → XP_016881312.1  zinc finger protein 532 isoform X8

      UniProtKB/TrEMBL
      B3KXW2

    34. XM_017025829.2 → XP_016881318.1  zinc finger protein 532 isoform X13

    35. XM_017025809.2 → XP_016881298.1  zinc finger protein 532 isoform X1

      UniProtKB/TrEMBL
      B3KXW2

    36. XM_047437602.1 → XP_047293558.1  zinc finger protein 532 isoform X10

    37. XM_047437604.1 → XP_047293560.1  zinc finger protein 532 isoform X12

    38. XM_011526067.3 → XP_011524369.1  zinc finger protein 532 isoform X18

      Conserved Domains (2) summary
      sd00017
      Location:785 → 805
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12756
      Location:834 → 871
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)

    RNA

    1. XR_935229.3 RNA Sequence

    2. XR_007066180.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060942.1 Alternate T2T-CHM13v2.0

      Range
      59064004..59187774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054318749.1 → XP_054174724.1  zinc finger protein 532 isoform X3

    2. XM_054318757.1 → XP_054174732.1  zinc finger protein 532 isoform X4

    3. XM_054318774.1 → XP_054174749.1  zinc finger protein 532 isoform X15

    4. XM_054318775.1 → XP_054174750.1  zinc finger protein 532 isoform X16

    5. XM_054318763.1 → XP_054174738.1  zinc finger protein 532 isoform X6

    6. XM_054318745.1 → XP_054174720.1  zinc finger protein 532 isoform X2

    7. XM_054318753.1 → XP_054174728.1  zinc finger protein 532 isoform X3

    8. XM_054318758.1 → XP_054174733.1  zinc finger protein 532 isoform X4

    9. XM_054318762.1 → XP_054174737.1  zinc finger protein 532 isoform X5

    10. XM_054318767.1 → XP_054174742.1  zinc finger protein 532 isoform X7

      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6

    11. XM_054318769.1 → XP_054174744.1  zinc finger protein 532 isoform X11

    12. XM_054318776.1 → XP_054174751.1  zinc finger protein 532 isoform X17

    13. XM_054318756.1 → XP_054174731.1  zinc finger protein 532 isoform X4

    14. XM_054318773.1 → XP_054174748.1  zinc finger protein 532 isoform X15

    15. XM_054318744.1 → XP_054174719.1  zinc finger protein 532 isoform X2

    16. XM_054318751.1 → XP_054174726.1  zinc finger protein 532 isoform X3

    17. XM_054318764.1 → XP_054174739.1  zinc finger protein 532 isoform X7

      UniProtKB/Swiss-Prot
      Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6

    18. XM_054318747.1 → XP_054174722.1  zinc finger protein 532 isoform X3

    19. XM_054318754.1 → XP_054174729.1  zinc finger protein 532 isoform X3

    20. XM_054318750.1 → XP_054174725.1  zinc finger protein 532 isoform X3

    21. XM_054318752.1 → XP_054174727.1  zinc finger protein 532 isoform X3

    22. XM_054318759.1 → XP_054174734.1  zinc finger protein 532 isoform X4

    23. XM_054318746.1 → XP_054174721.1  zinc finger protein 532 isoform X3

    24. XM_054318755.1 → XP_054174730.1  zinc finger protein 532 isoform X4

    25. XM_054318760.1 → XP_054174735.1  zinc finger protein 532 isoform X5

    26. XM_054318748.1 → XP_054174723.1  zinc finger protein 532 isoform X3

    27. XM_054318761.1 → XP_054174736.1  zinc finger protein 532 isoform X5

    28. XM_054318778.1 → XP_054174753.1  zinc finger protein 532 isoform X19

    29. XM_054318772.1 → XP_054174747.1  zinc finger protein 532 isoform X14

    30. XM_054318766.1 → XP_054174741.1  zinc finger protein 532 isoform X9

    31. XM_054318765.1 → XP_054174740.1  zinc finger protein 532 isoform X8

    32. XM_054318771.1 → XP_054174746.1  zinc finger protein 532 isoform X13

    33. XM_054318743.1 → XP_054174718.1  zinc finger protein 532 isoform X1

    34. XM_054318768.1 → XP_054174743.1  zinc finger protein 532 isoform X10

    35. XM_054318770.1 → XP_054174745.1  zinc finger protein 532 isoform X12

    36. XM_054318777.1 → XP_054174752.1  zinc finger protein 532 isoform X18

    RNA

    1. XR_008485002.1 RNA Sequence

    2. XR_008485003.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HCE3.2 GenPept UniProtKB/Swiss-Prot:Q9HCE3

    Gene LinkOut

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