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    SAG21 senescence-associated gene 21 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828053, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SAG21
    Official Full Name
    senescence-associated gene 21
    Primary source
    TAIR:AT4G02380
    Locus tag
    AT4G02380
    See related
    Araport:AT4G02380
    Gene type
    protein coding
    RNA name
    miRNA
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana late embryogenensis abundant like 5; AtLEA5; senescence-associated gene 21; T14P8.2; T14P8_2
    Summary
    Encodes AtLEA5 (late embryogenesis abundant like protein). Also known as SENESCENCE-ASSOCIATED GENE 21 (SAG21). Has a role on oxidative stress tolerance. mRNA levels are elevated in response to various stresses.
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    Genomic context

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    See SAG21 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (1046042..1047105, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein, putative (Protein of unknown function, DUF538) Neighboring gene pectinesterase (Protein of unknown function, DUF538) Neighboring gene microRNA ath-MIR2936 precursor Neighboring gene poly(ADP-ribose) polymerase Neighboring gene U3 ribonucleoprotein (Utp) family protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel function for a redox-related LEA protein (SAG21/AtLEA5) in root development and biotic stress responses. Salleh FM, et al. Plant Cell Environ, 2012 Feb. PMID 21736589
    2. Differential SAGE analysis in Arabidopsis uncovers increased transcriptome complexity in response to low temperature. Robinson SJ, et al. BMC Genomics, 2008 Sep 22. PMID 18808718, Free PMC Article
    3. Yeast complementation reveals a role for an Arabidopsis thaliana late embryogenesis abundant (LEA)-like protein in oxidative stress tolerance. Mowla SB, et al. Plant J, 2006 Dec. PMID 17092320
    4. Arabidopsis transcriptome profiling indicates that multiple regulatory pathways are activated during cold acclimation in addition to the CBF cold response pathway. Fowler S, et al. Plant Cell, 2002 Aug. PMID 12172015, Free PMC Article
    5. Monitoring the expression pattern of 1300 Arabidopsis genes under drought and cold stresses by using a full-length cDNA microarray. Seki M, et al. Plant Cell, 2001 Jan. PMID 11158529, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    • mature miRNA accession:MIMAT0014140
    NM_001084877.1
    NM_001340372.1
    NM_116471.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in leaf senescence IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to absence of light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    NOT involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to ethylene IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to insect IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to oxidative stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to reactive oxygen species IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    senescence-associated gene 21
    NP_001078346.1
    • senescence-associated gene 21 (SAG21); CONTAINS InterPro DOMAIN/s: Late embryogenesis abundant protein, group 3 (InterPro:IPR004926); BEST Arabidopsis thaliana protein match is: Late embryogenesis abundant 3 (LEA3) family protein (TAIR:AT1G02820.1); Has 166 Blast hits to 166 proteins in 34 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 166; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).
    NP_567231.1
    • senescence-associated gene 21 (SAG21); CONTAINS InterPro DOMAIN/s: Late embryogenesis abundant protein, group 3 (InterPro:IPR004926); BEST Arabidopsis thaliana protein match is: Late embryogenesis abundant 3 (LEA3) family protein (TAIR:AT1G02820.1); Has 181 Blast hits to 176 proteins in 36 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 181; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1046042..1047105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116471.4 → NP_567231.1  senescence-associated gene 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567231.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MSE1, C0Z336, O81295, Q93WF6
      UniProtKB/TrEMBL
      A0A178UUV1, A0A5S9XP64, A0A654FL74
      Conserved Domains (1) summary
      pfam03242
      Location:1 → 93
      LEA_3; Late embryogenesis abundant protein

    2. NM_001340372.1 → NP_001328319.1  senescence-associated gene 21 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B4A1
      Conserved Domains (1) summary
      pfam03242
      Location:96 → 188
      LEA_3; Late embryogenesis abundant protein

    3. NM_001084877.1 → NP_001078346.1  senescence-associated gene 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078346.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93WF6
      Conserved Domains (1) summary
      pfam03242
      Location:2 → 74
      LEA_3; Late embryogenesis abundant protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93WF6.1

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