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    IAA14 indole-3-acetic acid inducible 14 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827102, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IAA14
    Official Full Name
    indole-3-acetic acid inducible 14
    Primary source
    TAIR:AT4G14550
    Locus tag
    AT4G14550
    See related
    Araport:AT4G14550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DL3315C; FCAALL.254; indole-3-acetic acid inducible 14; SLR; SOLITARY ROOT
    Summary
    IAA14 is a member of the Aux/IAA protein family. Involved in lateral root development. Gain of function mutation decreases auxin-inducible gene expression. Protein is localized to the nucleus. Expressed in stele and root tip epidermis. Functions as a negative regulator of ARF7/19.
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    Genomic context

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    See IAA14 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (8347822..8350263, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene indole-3-acetic acid inducible

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aux/IAA14 Regulates microRNA-Mediated Cold Stress Response in Arabidopsis Roots. Aslam M, et al. Int J Mol Sci, 2020 Nov 10. PMID 33182739, Free PMC Article
    2. Lateral root formation is blocked by a gain-of-function mutation in the SOLITARY-ROOT/IAA14 gene of Arabidopsis. Fukaki H, et al. Plant J, 2002 Jan. PMID 11862947
    3. Auxin-induced SCFTIR1-Aux/IAA interaction involves stable modification of the SCFTIR1 complex. Kepinski S, et al. Proc Natl Acad Sci U S A, 2004 Aug 17. PMID 15295098, Free PMC Article
    4. A Gibberellin-Mediated DELLA-NAC Signaling Cascade Regulates Cellulose Synthesis in Rice. Huang D, et al. Plant Cell, 2015 Jun. PMID 26002868, Free PMC Article
    5. LBD18 and IAA14 antagonistically interact with ARF7 via the invariant Lys and acidic residues of the OPCA motif in the PB1 domain. Nguyen UT, et al. Planta, 2023 Jun 24. PMID 37354348

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LBD18 and IAA14 antagonistically interact with ARF7 via the invariant Lys and acidic residues of the OPCA motif in the PB1 domain.
      Title: LBD18 and IAA14 antagonistically interact with ARF7 via the invariant Lys and acidic residues of the OPCA motif in the PB1 domain.
    2. Aux/IAA14 Regulates microRNA-Mediated Cold Stress Response in Arabidopsis Roots.
      Title: Aux/IAA14 Regulates microRNA-Mediated Cold Stress Response in Arabidopsis Roots.
    3. Reduced upregulation of glycolipid synthase and phospholipase genes in these mutants under Pi-deficient conditions indicates that IAA14 and ARF7/19 affect membrane lipid remodeling at the level of transcription.
      Title: Involvement of auxin signaling mediated by IAA14 and ARF7/19 in membrane lipid remodeling during phosphate starvation.
    4. There are functional differences among the Aux/IAA gene family members MSG2, AXR2, and SLR.
      Title: Specificity and similarity of functions of the Aux/IAA genes in auxin signaling of Arabidopsis revealed by promoter-exchange experiments among MSG2/IAA19, AXR2/IAA7, and SLR/IAA14.
    5. Tissue-specific expression of a stabilized Aux/IAA protein allows analysis of tissue-specific auxin responses in LR development by inactivating ARF functions.
      Title: Tissue-specific expression of stabilized SOLITARY-ROOT/IAA14 alters lateral root development in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001340945.1
    NM_001340946.1
    NM_001340947.1
    NM_117535.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lateral root morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to auxin TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    indole-3-acetic acid inducible 14
    NP_193191.2
    • indole-3-acetic acid inducible 14 (IAA14); CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), AUX/IAA protein (InterPro:IPR003311); BEST Arabidopsis thaliana protein match is: indole-3-acetic acid 7 (TAIR:AT3G23050.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      8347822..8350263 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117535.5 → NP_193191.2  indole-3-acetic acid inducible 14 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193191.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23311, Q38832, Q9C5W8
      UniProtKB/TrEMBL
      A0A178V1G8, A0A384LC96, D3K0G9, Q0WRB1
      Conserved Domains (1) summary
      pfam02309
      Location:5 → 219
      AUX_IAA; AUX/IAA family

    2. NM_001340945.1 → NP_001329483.1  indole-3-acetic acid inducible 14 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B7U4, D3K0G9

    3. NM_001340946.1 → NP_001329484.1  indole-3-acetic acid inducible 14 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B7U9, D3K0G9
      Conserved Domains (1) summary
      pfam02309
      Location:5 → 195
      AUX_IAA; AUX/IAA family

    4. NM_001340947.1 → NP_001329482.1  indole-3-acetic acid inducible 14 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z2L3, E1A7H5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38832.2

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