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    VPS2.1 SNF7 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815211, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VPS2.1
    Official Full Name
    SNF7 family protein
    Primary source
    TAIR:AT2G06530
    Locus tag
    AT2G06530
    See related
    Araport:AT2G06530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T12H3.8; T12H3_8; VPS2
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    Genomic context

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    See VPS2.1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (2588523..2590531, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene replication protein A 1A Neighboring gene photosystem II subunit X Neighboring gene pseudo Neighboring gene TTF-type zinc finger protein with HAT dimerization domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ESCRT-III-interacting deubiquitinating enzyme AMSH3 is essential for degradation of ubiquitinated membrane proteins in Arabidopsis thaliana. Katsiarimpa A, et al. Plant Cell Physiol, 2014 Apr. PMID 24486765
    2. Multivesicular bodies mature from the trans-Golgi network/early endosome in Arabidopsis. Scheuring D, et al. Plant Cell, 2011 Sep. PMID 21934143, Free PMC Article
    3. The deubiquitinating enzyme AMSH1 and the ESCRT-III subunit VPS2.1 are required for autophagic degradation in Arabidopsis. Katsiarimpa A, et al. Plant Cell, 2013 Jun. PMID 23800962, Free PMC Article
    4. The Arabidopsis deubiquitinating enzyme AMSH3 interacts with ESCRT-III subunits and regulates their localization. Katsiarimpa A, et al. Plant Cell, 2011 Aug. PMID 21810997, Free PMC Article
    5. The Arabidopsis Endosomal Sorting Complex Required for Transport III Regulates Internal Vesicle Formation of the Prevacuolar Compartment and Is Required for Plant Development. Cai Y, et al. Plant Physiol, 2014 Jul. PMID 24812106, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_001335305.1
    NM_126650.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within intralumenal vesicle formation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vacuolar transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ESCRT III complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in endosome membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in late endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in multivesicular body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SNF7 family protein
    NP_565336.1
    • VPS2.1; CONTAINS InterPro DOMAIN/s: Snf7 (InterPro:IPR005024); BEST Arabidopsis thaliana protein match is: vacuolar protein sorting-associated protein 2.3 (TAIR:AT1G03950.1); Has 2524 Blast hits to 2516 proteins in 271 species: Archae - 17; Bacteria - 20; Metazoa - 1106; Fungi - 512; Plants - 555; Viruses - 5; Other Eukaryotes - 309 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      2588523..2590531 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126650.4 → NP_565336.1  SNF7 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565336.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q701A4, Q701B3, Q701B7, Q701C5, Q701E0, Q701E1, Q701E3, Q701F9, Q701G8, Q701J8, Q8L915, Q9SKI2
      UniProtKB/TrEMBL
      A0A178VT12, A0A5S9WXS7
      Conserved Domains (1) summary
      pfam03357
      Location:18 → 187
      Snf7

    2. NM_001335305.1 → NP_001324346.1  SNF7 family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AZU4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SKI2.2

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