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    ST7 suppression of tumorigenicity 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296911, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ST7provided by RGD
    Official Full Name
    suppression of tumorigenicity 7provided by RGD
    Primary source
    RGD:1303148
    See related
    EnsemblRapid:ENSRNOG00000056243 AllianceGenome:RGD:1303148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Orthologous to human ST7 (suppression of tumorigenicity 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 54.0), Lung (RPKM 39.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See ST7 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (47007568..47255639)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (46041655..46289745)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (45000223..45247793)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene MET proto-oncogene, receptor tyrosine kinase Neighboring gene capping actin protein of muscle Z-line subunit alpha 2 Neighboring gene 60S ribosomal protein L23a-like Neighboring gene uncharacterized LOC134486733 Neighboring gene Wnt family member 2 Neighboring gene ankyrin repeat, SAM and basic leucine zipper domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Comparative analyses of multi-species sequences from targeted genomic regions. Thomas JW, et al. Nature, 2003 Aug 14. PMID 12917688
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC124523

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    suppressor of tumorigenicity 7 protein
    Names
    suppressor of tumorigenicity protein 7

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004102.1 → NP_001004102.1  suppressor of tumorigenicity 7 protein

      See identical proteins and their annotated locations for NP_001004102.1

      Status: PROVISIONAL

      Source sequence(s)
      DP000027
      UniProtKB/TrEMBL
      A0A0G2JYP8, Q2IBC9
      Related
      ENSRNOP00000071529.1, ENSRNOT00000084736.3
      Conserved Domains (1) summary
      pfam04184
      Location:19 → 553
      ST7; ST7 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      47007568..47255639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236132.5 → XP_006236194.1  suppressor of tumorigenicity 7 protein isoform X1

      See identical proteins and their annotated locations for XP_006236194.1

      UniProtKB/Swiss-Prot
      Q2IBD0, Q499P1
      UniProtKB/TrEMBL
      A6IE32
      Related
      ENSRNOP00000108963.1, ENSRNOT00000163353.1
      Conserved Domains (1) summary
      pfam04184
      Location:19 → 576
      ST7; ST7 protein

    2. XM_039107264.2 → XP_038963192.1  suppressor of tumorigenicity 7 protein isoform X2

      Conserved Domains (1) summary
      pfam04184
      Location:19 → 571
      ST7; ST7 protein

    3. XM_063285725.1 → XP_063141795.1  suppressor of tumorigenicity 7 protein isoform X3

      UniProtKB/TrEMBL
      A0A0G2JYP8

    4. XM_039107266.2 → XP_038963194.1  suppressor of tumorigenicity 7 protein isoform X11

      UniProtKB/TrEMBL
      A6IE37
      Conserved Domains (1) summary
      cl19051
      Location:19 → 434
      ST7; Suppression of tumorigenicity 7

    5. XM_039107267.2 → XP_038963195.1  suppressor of tumorigenicity 7 protein isoform X12

      Conserved Domains (1) summary
      cl19051
      Location:19 → 360
      ST7; Suppression of tumorigenicity 7

    6. XM_063285732.1 → XP_063141802.1  suppressor of tumorigenicity 7 protein isoform X14

    7. XM_063285729.1 → XP_063141799.1  suppressor of tumorigenicity 7 protein isoform X7

    8. XM_063285733.1 → XP_063141803.1  suppressor of tumorigenicity 7 protein isoform X15

    9. XM_039107265.2 → XP_038963193.1  suppressor of tumorigenicity 7 protein isoform X5

      Conserved Domains (1) summary
      cd11557
      Location:11 → 498
      ST7; Suppression of tumorigenicity 7

    10. XM_063285731.1 → XP_063141801.1  suppressor of tumorigenicity 7 protein isoform X9

      Related
      ENSRNOP00000068731.3, ENSRNOT00000077961.3

    11. XM_063285726.1 → XP_063141796.1  suppressor of tumorigenicity 7 protein isoform X4

      UniProtKB/TrEMBL
      A0A0G2JTJ1, A6IE35
      Related
      ENSRNOP00000100155.1, ENSRNOT00000170669.1

    12. XM_063285730.1 → XP_063141800.1  suppressor of tumorigenicity 7 protein isoform X8

      UniProtKB/TrEMBL
      A6IE36
      Related
      ENSRNOP00000103386.1, ENSRNOT00000129485.1

    13. XM_063285728.1 → XP_063141798.1  suppressor of tumorigenicity 7 protein isoform X4

      UniProtKB/TrEMBL
      A0A0G2JTJ1, A6IE35

    14. XM_063285727.1 → XP_063141797.1  suppressor of tumorigenicity 7 protein isoform X4

      UniProtKB/TrEMBL
      A0A0G2JTJ1, A6IE35

    15. XM_006236134.5 → XP_006236196.1  suppressor of tumorigenicity 7 protein isoform X6

      See identical proteins and their annotated locations for XP_006236196.1

      UniProtKB/TrEMBL
      A0A0G2KBB5, A6IE33
      Related
      ENSRNOP00000075727.2, ENSRNOT00000078255.3
      Conserved Domains (1) summary
      pfam04184
      Location:4 → 530
      ST7; ST7 protein

    16. XM_006236135.5 → XP_006236197.1  suppressor of tumorigenicity 7 protein isoform X10

      See identical proteins and their annotated locations for XP_006236197.1

      UniProtKB/TrEMBL
      A6IE34
      Conserved Domains (1) summary
      pfam04184
      Location:4 → 507
      ST7; ST7 protein

    17. XM_039107269.2 → XP_038963197.1  suppressor of tumorigenicity 7 protein isoform X13

      Conserved Domains (1) summary
      cd11557
      Location:1 → 377
      ST7; Suppression of tumorigenicity 7

    18. XM_039107270.2 → XP_038963198.1  suppressor of tumorigenicity 7 protein isoform X13

      Conserved Domains (1) summary
      cd11557
      Location:1 → 377
      ST7; Suppression of tumorigenicity 7

    RNA

    1. XR_005503176.2 RNA Sequence

    2. XR_010065617.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2IBD0.1 GenPept UniProtKB/Swiss-Prot:Q2IBD0

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