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    GLDC glycine decarboxylase [ Bos taurus (domestic cattle) ]

    Gene ID: 507688, updated on 27-Dec-2024

    Summary

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    Official Symbol
    GLDCprovided by VGNC
    Official Full Name
    glycine decarboxylaseprovided by VGNC
    Primary source
    VGNC:VGNC:29395
    See related
    BGD:BT20197; Ensembl:ENSBTAG00000025903
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See GLDC in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (38219953..38308310)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene acyl-protein thioesterase 2-like Neighboring gene small nucleolar RNA SNORA7 Neighboring gene uncharacterized LOC112447747 Neighboring gene ubiquitin like with PHD and ring finger domains 2 Neighboring gene uncharacterized LOC101902321

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glycine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glycine dehydrogenase (decarboxylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycine decarboxylation via glycine cleavage system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of glycine cleavage complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine dehydrogenase (decarboxylating), mitochondrial
    NP_001179880.1
    XP_024851302.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192951.1 → NP_001179880.1  glycine dehydrogenase (decarboxylating), mitochondrial

      See identical proteins and their annotated locations for NP_001179880.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000008
      UniProtKB/TrEMBL
      E1BJQ1
      Related
      ENSBTAP00000036556.4, ENSBTAT00000036700.5
      Conserved Domains (1) summary
      PRK05367
      Location:57 → 1009
      PRK05367; glycine dehydrogenase; Provisional

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      38219953..38308310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024995534.2 → XP_024851302.1  glycine dehydrogenase (decarboxylating), mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0AAA9TQS0
      Related
      ENSBTAP00000098770.1, ENSBTAT00000115297.1
      Conserved Domains (1) summary
      PRK05367
      Location:57 → 1030
      PRK05367; glycine dehydrogenase; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version

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