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    ECB2 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838121, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ECB2
    Official Full Name
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    TAIR:AT1G15510
    Locus tag
    AT1G15510
    See related
    Araport:AT1G15510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS EARLY CHLOROPLAST BIOGENESIS2; ATECB2; EARLY CHLOROPLAST BIOGENESIS2; T16N11.2; T16N11_2; VAC1; VANILLA CREAM 1
    Summary
    Encodes a pentatricopeptide repeat protein required for chloroplast transcript accD RNA editing and early chloroplast biogenesis.
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    Genomic context

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    See ECB2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (5329064..5331711)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene TLC ATP/ADP transporter Neighboring gene pleiotropic drug resistance 12 Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A point mutation in the pentatricopeptide repeat motif of the AtECB2 protein causes delayed chloroplast development. Cao ZL, et al. J Integr Plant Biol, 2011 Apr. PMID 21294841
    2. AtECB2, a pentatricopeptide repeat protein, is required for chloroplast transcript accD RNA editing and early chloroplast biogenesis in Arabidopsis thaliana. Yu QB, et al. Plant J, 2009 Sep. PMID 19500301
    3. Porphobilinogen deaminase HEMC interacts with the PPR-protein AtECB2 for chloroplast RNA editing. Huang C, et al. Plant J, 2017 Nov. PMID 28850756
    4. Editing of accD and ndhF chloroplast transcripts is partially affected in the Arabidopsis vanilla cream1 mutant. Tseng CC, et al. Plant Mol Biol, 2010 Jun. PMID 20143129
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results showed that both porphobilinogen deaminase (HEMC) and multiple organellar RNA editing factor (MORF) proteins are associated with AtECB2 for RNA editing in plastids.
      Title: Porphobilinogen deaminase HEMC interacts with the PPR-protein AtECB2 for chloroplast RNA editing.
    2. An allelic mutant of the AtECB2 gene, ecb2-2, which showed delayed greening phenotype but could complete their life cycle, was isolated.
      Title: A point mutation in the pentatricopeptide repeat motif of the AtECB2 protein causes delayed chloroplast development.
    3. AtECB2 regulated the RNA editing of the chloroplast transcript accD, and is essential for the early stages of chloroplast biogenesis. [ECB2]
      Title: AtECB2, a pentatricopeptide repeat protein, is required for chloroplast transcript accD RNA editing and early chloroplast biogenesis in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    NM_101420.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_173004.1
    • EARLY CHLOROPLAST BIOGENESIS2 (ECB2); CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR) superfamily protein (TAIR:AT4G18750.1); Has 49765 Blast hits to 13993 proteins in 266 species: Archae - 0; Bacteria - 6; Metazoa - 64; Fungi - 140; Plants - 48782; Viruses - 0; Other Eukaryotes - 773 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5329064..5331711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101420.2 → NP_173004.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173004.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      E2FJQ9, Q9M9E2
      UniProtKB/TrEMBL
      A0A5S9ULX7, A0A654EKX3, A0A7G2DQY5
      Conserved Domains (2) summary
      PLN03077
      Location:5 → 866
      PLN03077; Protein ECB2; Provisional
      sd00004
      Location:565 → 592
      PPR; PPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M9E2.1

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