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    Vacuolar iron transporter (VIT) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838710, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Vacuolar iron transporter (VIT) family protein
    Primary source
    TAIR:AT1G21140
    Locus tag
    AT1G21140
    See related
    Araport:AT1G21140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtVTL1; T22I11.3; T22I11_3; Vacuolar Iron Transporter-Like 1; VTL1
    Summary
    The gene encodes nodulin-like1 whose transcript abundance was repressed under conditions of Fe-deficient growth.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (7404328..7405426)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Mitochondrial transcription termination factor family protein Neighboring gene eukaryotic translation initiation factor 2 (eIF-2) family protein Neighboring gene Exocyst complex component SEC5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency. Yan JY, et al. Plant Physiol, 2016 Jul. PMID 27208259, Free PMC Article
    2. Vacuolar-Iron-Transporter1-Like proteins mediate iron homeostasis in Arabidopsis. Gollhofer J, et al. PLoS One, 2014. PMID 25360591, Free PMC Article
    3. Members of a small family of nodulin-like genes are regulated under iron deficiency in roots of Arabidopsis thaliana. Gollhofer J, et al. Plant Physiol Biochem, 2011 May. PMID 21411332
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. WRKY46 binds to the promoter region of VITL1.
      Title: A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency.
    2. The gene transcripts for nodulin-like1 showed decreased abundance following 6 h of Fe-deficient growth.
      Title: Members of a small family of nodulin-like genes are regulated under iron deficiency in roots of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_101968.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables iron ion transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables manganese ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in intracellular manganese ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular sequestering of iron ion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to iron ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in vacuolar membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Vacuolar iron transporter (VIT) family protein
    NP_173538.2
    • Vacuolar iron transporter (VIT) family protein; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF125, transmembrane (InterPro:IPR008217); BEST Arabidopsis thaliana protein match is: Vacuolar iron transporter (VIT) family protein (TAIR:AT3G43660.1); Has 1867 Blast hits to 1856 proteins in 645 species: Archae - 60; Bacteria - 1279; Metazoa - 0; Fungi - 103; Plants - 211; Viruses - 0; Other Eukaryotes - 214 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7404328..7405426
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101968.3 → NP_173538.2  Vacuolar iron transporter (VIT) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173538.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LPU9
      UniProtKB/TrEMBL
      A0A178W9M6, A0A5S9VE67
      Conserved Domains (1) summary
      cl00278
      Location:29 → 169
      CCC1_like; CCC1-related family of proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LPU9.1

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