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    TCP2 TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827568, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TCP2
    Official Full Name
    TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2
    Primary source
    TAIR:AT4G18390
    Locus tag
    AT4G18390
    See related
    Araport:AT4G18390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cycloidea and PCF transcription factor 2; F28J12.50; F28J12_50; TEOSINTE BRANCHED 1
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    Genomic context

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    See TCP2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (10162922..10165583, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RNA-binding KH domain-containing protein Neighboring gene F-box family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a consensus DNA-binding site for the TCP domain transcription factor TCP2 and its important roles in the growth and development of Arabidopsis. He Z, et al. Mol Biol Rep, 2021 Mar. PMID 33689093
    2. Alterations of plant architecture and phase transition by the phytoplasma virulence factor SAP11. Chang SH, et al. J Exp Bot, 2018 Nov 26. PMID 30165491, Free PMC Article
    3. TCP2 positively regulates HY5/HYH and photomorphogenesis in Arabidopsis. He Z, et al. J Exp Bot, 2016 Feb. PMID 26596765, Free PMC Article
    4. Protein interaction mapping reveals widespread targeting of development-related host transcription factors by phytoplasma effectors. Correa Marrero M, et al. Plant J, 2024 Feb. PMID 37965720
    5. Evolution of double positive autoregulatory feedback loops in CYCLOIDEA2 clade genes is associated with the origin of floral zygomorphy. Yang X, et al. Plant Cell, 2012 May. PMID 22649271, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification of a consensus DNA-binding site for the TCP domain transcription factor TCP2 and its important roles in the growth and development of Arabidopsis.
      Title: Identification of a consensus DNA-binding site for the TCP domain transcription factor TCP2 and its important roles in the growth and development of Arabidopsis.
    2. TB/CYC (TEOSINTE-BRANCHED/CYCLOIDEA)-TCP1 & TCP2 are destabilized by phytoplasma SAP11 effectors, leading to the proliferation of axillary meristems.
      Title: Alterations of plant architecture and phase transition by the phytoplasma virulence factor SAP11.
    3. light affected TCP2 expression in a wavelength-dependent manner and TCP2 positively regulates mRNA expression of HYH and HY5.
      Title: TCP2 positively regulates HY5/HYH and photomorphogenesis in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084938.1
    NM_117950.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of development, heterochronic IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of photomorphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in response to blue light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2
    NP_001078407.1
    • ''TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2'' (TCP2); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: cell differentiation, positive regulation of development, heterochronic, regulation of transcription, leaf morphogenesis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), CYC/TB1, R domain (InterPro:IPR017888), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TEOSINTE BRANCHED 1, cycloidea, and PCF family 24 (TAIR:AT1G30210.2); Has 2182 Blast hits to 1888 proteins in 369 species: Archae - 0; Bacteria - 6; Metazoa - 128; Fungi - 15; Plants - 1699; Viruses - 0; Other Eukaryotes - 334 (source: NCBI BLink).
    NP_567553.1
    • ''TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2'' (TCP2); CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), CYC/TB1, R domain (InterPro:IPR017888), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TEOSINTE BRANCHED 1, cycloidea, and PCF family 24 (TAIR:AT1G30210.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10162922..10165583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117950.5 → NP_567553.1  TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567553.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49509, O81384, Q8LGF2, Q93V43
      UniProtKB/TrEMBL
      A0A178V414, A0A5S9XTQ7, A0A654FQN0
      Conserved Domains (1) summary
      PLN03106
      Location:18 → 365
      TCP2; Protein TCP2; Provisional

    2. NM_001084938.1 → NP_001078407.1  TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078407.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49509, O81384, Q8LGF2, Q93V43
      UniProtKB/TrEMBL
      A0A178V414, A0A5S9XTQ7, A0A654FQN0
      Conserved Domains (1) summary
      PLN03106
      Location:18 → 365
      TCP2; Protein TCP2; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93V43.1

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