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    Zincin-like metalloproteases family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836688, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Zincin-like metalloproteases family protein
    Primary source
    TAIR:AT5G65620
    Locus tag
    AT5G65620
    See related
    Araport:AT5G65620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K21L13.14; K21L13_14; OOP; organellar oligopeptidase; thimet metalloendopeptidase 1; TOP1
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    17
    Sequence:
    Chromosome: 5; NC_003076.8 (26221829..26225903)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene tRNA-Asn Neighboring gene global transcription factor group E7 Neighboring gene ncRNA Neighboring gene beta HLH protein 93

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts. Kmiec B, et al. Proc Natl Acad Sci U S A, 2013 Oct 1. PMID 24043784, Free PMC Article
    2. Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity. McConnell EW, et al. Plant Physiol, 2019 Apr. PMID 30510037, Free PMC Article
    3. The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response. Moreau M, et al. Plant J, 2013 Nov. PMID 24004003
    4. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701
    5. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. role in maintaining the proper level and dynamics of proteome oxidation during effector-triggered immunity
      Title: Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity.
    2. Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts. [Organellar oligopeptidase[ [OOP]
      Title: Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.
    3. Interacts with protein targets to mediate salicylic acid-dependent signaling necessary for the immune response to avirulent pathogens.
      Title: The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_125960.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    Zincin-like metalloproteases family protein
    NP_569013.1
    • Zincin-like metalloproteases family protein; FUNCTIONS IN: metalloendopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: cytosol, chloroplast, chloroplast stroma; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M3A/M3B, thimet/oligopeptidase F (InterPro:IPR001567); BEST Arabidopsis thaliana protein match is: Zincin-like metalloproteases family protein (TAIR:AT5G10540.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26221829..26225903
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345702.1 → NP_001332654.1  Zincin-like metalloproteases family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T3A4, A0A654GEE4
      Conserved Domains (1) summary
      cd06456
      Location:154 → 798
      M3A_DCP; Peptidase family M3, dipeptidyl carboxypeptidase (DCP)

    2. NM_125960.3 → NP_569013.1  Zincin-like metalloproteases family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_569013.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94AM1, Q9LSL3
      UniProtKB/TrEMBL
      A0A654GEE4
      Conserved Domains (2) summary
      cd06456
      Location:140 → 784
      M3A_DCP; Peptidase family M3 dipeptidyl carboxypeptidase (DCP)
      COG0339
      Location:93 → 786
      Dcp; Zn-dependent oligopeptidase [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94AM1.1

    Gene LinkOut

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