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    EMB2421 FAD/NAD(P)-binding oxidoreductase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839050, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB2421
    Official Full Name
    FAD/NAD(P)-binding oxidoreductase family protein
    Primary source
    TAIR:AT1G24340
    Locus tag
    AT1G24340
    See related
    Araport:AT1G24340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMB260; EMBRYO DEFECTIVE 2421; EMBRYO DEFECTIVE 260; F3I6.28; F3I6_28
    Summary
    A locus involved in embryogenesis. Mutations in this locus result in embryo lethality.
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    Genomic context

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    See EMB2421 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (8635187..8638986)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nuclear pore complex protein Neighboring gene Six-hairpin glycosidases superfamily protein Neighboring gene ARM repeat superfamily protein Neighboring gene Acid phosphatase/vanadium-dependent haloperoxidase-related protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis. Latimer S, et al. J Biol Chem, 2021 Nov. PMID 34626646, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis.
      Title: A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_102280.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-demethoxyubiquinol 3-hydroxylase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within ubiquinone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FAD/NAD(P)-binding oxidoreductase family protein
    NP_173844.2
    • EMBRYO DEFECTIVE 2421 (EMB2421); FUNCTIONS IN: monooxygenase activity; INVOLVED IN: embryo development ending in seed dormancy; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Monooxygenase, FAD-binding (InterPro:IPR002938); Has 5711 Blast hits to 5585 proteins in 1112 species: Archae - 4; Bacteria - 3878; Metazoa - 19; Fungi - 944; Plants - 66; Viruses - 0; Other Eukaryotes - 800 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8635187..8638986
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102280.4 → NP_173844.2  FAD/NAD(P)-binding oxidoreductase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173844.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W6V3, Q8GYJ7
      Conserved Domains (2) summary
      PRK06126
      Location:48 → 686
      PRK06126; hypothetical protein; Provisional
      cl21454
      Location:49 → 418
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version

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