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    PUM2 pumilio 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817468, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUM2
    Official Full Name
    pumilio 2
    Primary source
    TAIR:AT2G29190
    Locus tag
    AT2G29190
    See related
    Araport:AT2G29190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    APUM2; F16P2.43; F16P2_43; pumilio 2
    Summary
    Encodes a member of the Arabidopsis Pumilio (APUM) proteins containing PUF domain (eight repeats of approximately 36 amino acids each). PUF proteins regulate both mRNA stability and translation through sequence-specific binding to the 3' UTR of target mRNA transcripts.
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    Genomic context

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    See PUM2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Sequence:
    Chromosome: 2; NC_003071.7 (12543812..12548563, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pumilio 1 Neighboring gene splicing factor PWI domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of Arabidopsis thaliana PUF proteins--binding specificity and target candidates. Francischini CW, et al. FEBS J, 2009 Oct. PMID 19682068
    2. The Puf family of RNA-binding proteins in plants: phylogeny, structural modeling, activity and subcellular localization. Tam PP, et al. BMC Plant Biol, 2010 Mar 9. PMID 20214804, Free PMC Article
    3. Profiling of the Receptor for Activated C Kinase 1a (RACK1a) interaction network in Arabidopsis thaliana. Guo J, et al. Biochem Biophys Res Commun, 2019 Dec 3. PMID 31606202
    4. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    5. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001202701.1
    NM_128475.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    pumilio 2
    NP_001189630.1
    • pumilio 2 (PUM2); CONTAINS InterPro DOMAIN/s: Nucleic acid binding NABP (InterPro:IPR012940), Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: pumilio 1 (TAIR:AT2G29200.1).
    NP_180482.1
    • pumilio 2 (PUM2); FUNCTIONS IN: mRNA binding, RNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid binding NABP (InterPro:IPR012940), Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: pumilio 1 (TAIR:AT2G29200.1); Has 3838 Blast hits to 2002 proteins in 239 species: Archae - 0; Bacteria - 4; Metazoa - 765; Fungi - 1352; Plants - 848; Viruses - 0; Other Eukaryotes - 869 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12543812..12548563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128475.4 → NP_180482.1  pumilio 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180482.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WVV2, Q8LPN4, Q9ZW06
      UniProtKB/TrEMBL
      A0A178VXS6, A0A5S9X2E0
      Conserved Domains (2) summary
      cd07920
      Location:635 → 950
      Pumilio; Pumilio-family RNA binding domain
      pfam07990
      Location:277 → 632
      NABP; Nucleic acid binding protein NABP

    2. NM_001202701.1 → NP_001189630.1  pumilio 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189630.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WVV2, Q8LPN4, Q9ZW06
      UniProtKB/TrEMBL
      A0A178VXS6, A0A5S9X2E0
      Conserved Domains (2) summary
      cd07920
      Location:635 → 950
      Pumilio; Pumilio-family RNA binding domain
      pfam07990
      Location:277 → 632
      NABP; Nucleic acid binding protein NABP
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZW06.1

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