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    RNR2A ribonucleotide reductase 2A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821937, updated on 18-Sep-2024

    Summary

    Official Symbol
    RNR2A
    Official Full Name
    ribonucleotide reductase 2A
    Primary source
    TAIR:AT3G23580
    Locus tag
    AT3G23580
    See related
    Araport:AT3G23580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ribonucleotide reductase 2A; RNR2
    Summary
    Encodes one of the 3 ribonucleotide reductase (RNR) small subunit genes (RNR2A). Functionally redundant with the ribonucleotide reductase TSO2. mRNA was shown to specifically accumulate during the S-phase of the cell cycle in synchronized tobacco BY2 cells. Critical for cell cycle progression, DNA damage repair and plant development.
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    Genomic context

    See RNR2A in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (8459838..8462815)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene MATE efflux family protein Neighboring gene MATE efflux family protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Bibliography

    Pathways from PubChem

    Interactions

    General gene information

    NM_113261.4

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in cytoplasm  
    part_of ribonucleoside-diphosphate reductase complex PubMed 

    General protein information

    Preferred Names
    ribonucleotide reductase 2A
    NP_189000.1
    • ribonucleotide reductase 2A (RNR2A); CONTAINS InterPro DOMAIN/s: Ribonucleotide reductase-related (InterPro:IPR012348), Ribonucleotide reductase (InterPro:IPR000358), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078); BEST Arabidopsis thaliana protein match is: Ferritin/ribonucleotide reductase-like family protein (TAIR:AT3G27060.1); Has 9602 Blast hits to 9597 proteins in 2376 species: Archae - 34; Bacteria - 4358; Metazoa - 261; Fungi - 240; Plants - 185; Viruses - 729; Other Eukaryotes - 3795 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8459838..8462815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113261.4 → NP_189000.1  ribonucleotide reductase 2A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189000.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P50651, Q9LUH0
      UniProtKB/TrEMBL
      A0A178V929
      Conserved Domains (1) summary
      PLN02492
      Location:19 → 341
      PLN02492; ribonucleoside-diphosphate reductase
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