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FUS5 Proteasome component (PCI) domain protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839241, updated on 18-Sep-2024

Summary

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Official Symbol
FUS5
Official Full Name
Proteasome component (PCI) domain protein
Primary source
TAIR:AT1G02090
Locus tag
AT1G02090
See related
Araport:AT1G02090
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA COP9 SIGNALOSOME SUBUNIT 7; ATCSN7; CONSTITUTIVE PHOTOMORPHOGENIC 15; COP15; COP9 SIGNALOSOME SUBUNIT 7; CSN7; FUSCA 5; T7I23.25; T7I23_25
Summary
encodes a phosphoprotein that is a subunit of the COP9 signalosome. Mutants exhibit constitutive photomorphogenic phenotype.
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Genomic context

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See FUS5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (387277..389808, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene zinc ion-binding protein Neighboring gene transcription regulator Neighboring gene Leucine carboxyl methyltransferase Neighboring gene bZIP domain class transcription factor (DUF630 and DUF632)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis FUSCA5 encodes a novel phosphoprotein that is a component of the COP9 complex. Karniol B, et al. Plant Cell, 1999 May. PMID 10330469, Free PMC Article
  2. The Arabidopsis COP9 signalosome subunit 7 is a model PCI domain protein with subdomains involved in COP9 signalosome assembly. Dessau M, et al. Plant Cell, 2008 Oct. PMID 18854373, Free PMC Article
  3. Crystal structure and versatile functional roles of the COP9 signalosome subunit 1. Lee JH, et al. Proc Natl Acad Sci U S A, 2013 Jul 16. PMID 23818606, Free PMC Article
  4. CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome. Wang X, et al. Mol Biol Cell, 2002 Feb. PMID 11854419, Free PMC Article
  5. Arabidopsis cop8 and fus4 mutations define the same gene that encodes subunit 4 of the COP9 signalosome. Serino G, et al. Plant Cell, 1999 Oct. PMID 10521526, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CSN is a negative regulator of RNR activity in Arabidopsis.
    Title: COP9 signalosome subunit 7 from Arabidopsis interacts with and regulates the small subunit of ribonucleotide reductase (RNR2).
  2. CSN7 contains a PCI motif and is involved in COP9 signalosome assembly.
    Title: The Arabidopsis COP9 signalosome subunit 7 is a model PCI domain protein with subdomains involved in COP9 signalosome assembly.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_100089.3
NM_179245.3
NM_202010.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within COP9 signalosome assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within photomorphogenesis TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within protein deneddylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome TAS
Traceable Author Statement
more info
 PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Proteasome component (PCI) domain protein
NP_563645.1
  • FUSCA 5 (FUS5); CONTAINS InterPro DOMAIN/s: Proteasome component (PCI) domain (InterPro:IPR000717); Has 689 Blast hits to 689 proteins in 163 species: Archae - 0; Bacteria - 0; Metazoa - 405; Fungi - 166; Plants - 80; Viruses - 0; Other Eukaryotes - 38 (source: NCBI BLink).
NP_849576.1
  • FUSCA 5 (FUS5); CONTAINS InterPro DOMAIN/s: Proteasome component (PCI) domain (InterPro:IPR000717); Has 683 Blast hits to 683 proteins in 162 species: Archae - 0; Bacteria - 0; Metazoa - 406; Fungi - 161; Plants - 78; Viruses - 0; Other Eukaryotes - 38 (source: NCBI BLink).
NP_973739.1
  • FUSCA 5 (FUS5); CONTAINS InterPro DOMAIN/s: Proteasome component (PCI) domain (InterPro:IPR000717); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    387277..389808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100089.3 → NP_563645.1  Proteasome component (PCI) domain protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_563645.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81247, Q94JU3
    UniProtKB/TrEMBL
    A0A178W722, A0A5S9S6P8
    Conserved Domains (1) summary
    smart00088
    Location:86 → 177
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15

  2. NM_179245.3 → NP_849576.1  Proteasome component (PCI) domain protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849576.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9S6P8
    Conserved Domains (1) summary
    smart00088
    Location:86 → 177
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15

  3. NM_202010.3 → NP_973739.1  Proteasome component (PCI) domain protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973739.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W6J6, A0A5S9S6P8, F4HVW0
    Conserved Domains (1) summary
    smart00088
    Location:86 → 177
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94JU3.1

Gene LinkOut

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