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    ALIS1 ALA-interacting subunit 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820456, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ALIS1
    Official Full Name
    ALA-interacting subunit 1
    Primary source
    TAIR:AT3G12740
    Locus tag
    AT3G12740
    See related
    Araport:AT3G12740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALA-interacting subunit 1
    Summary
    Physically interacts with ALA3, and is required for the phospholipid translocase activity of ALA3.
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    Genomic context

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    See ALIS1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (4049309..4051775)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene myb domain protein 67 Neighboring gene Homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene zinc transporter 1 precursor Neighboring gene defective in cullin neddylation protein Neighboring gene mitochondrial editing factor 22 Neighboring gene ubiquitin-conjugating enzyme family protein Neighboring gene phosphoglycerate kinase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis P4-ATPase ALA3 localizes to the golgi and requires a beta-subunit to function in lipid translocation and secretory vesicle formation. Poulsen LR, et al. Plant Cell, 2008 Mar. PMID 18344284, Free PMC Article
    2. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_112110.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phospholipid transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    ALA-interacting subunit 1
    NP_566435.1
    • ALA-interacting subunit 1 (ALIS1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF284, transmembrane eukaryotic (InterPro:IPR005045); BEST Arabidopsis thaliana protein match is: LEM3 (ligand-effect modulator 3) family protein / CDC50 family protein (TAIR:AT1G54320.1); Has 864 Blast hits to 864 proteins in 218 species: Archae - 0; Bacteria - 0; Metazoa - 252; Fungi - 234; Plants - 160; Viruses - 0; Other Eukaryotes - 218 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4049309..4051775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112110.4 → NP_566435.1  ALA-interacting subunit 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566435.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LTW0
      UniProtKB/TrEMBL
      A0A178VCJ4, A0A5S9XCX0, A0A654FGT9
      Conserved Domains (1) summary
      pfam03381
      Location:71 → 330
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LTW0.1

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