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    NRPC2 nuclear RNA polymerase C2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834550, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NRPC2
    Official Full Name
    nuclear RNA polymerase C2
    Primary source
    TAIR:AT5G45140
    Locus tag
    AT5G45140
    See related
    Araport:AT5G45140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K18C1.1; K18C1_1; nuclear RNA polymerase C2
    Summary
    Encodes a subunit of RNA polymerase III (aka RNA polymerase C).
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    Genomic context

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    See NRPC2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    40
    Sequence:
    Chromosome: 5; NC_003076.8 (18247149..18258197, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene Ras small GTP-binding family protein Neighboring gene RNAse THREE-like protein 3 Neighboring gene Root hair defective 3 GTP-binding protein (RHD3) Neighboring gene Haloacid dehalogenase-like hydrolase (HAD) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sex-biased lethality or transmission of defective transcription machinery in Arabidopsis. Onodera Y, et al. Genetics, 2008 Sep. PMID 18723889, Free PMC Article
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001344590.1
    NM_001344591.1
    NM_123882.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribonucleoside binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in megagametogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    nuclear RNA polymerase C2
    NP_199327.4
    • nuclear RNA polymerase C2 (NRPC2); FUNCTIONS IN: DNA-directed RNA polymerase activity, ribonucleoside binding, DNA binding; INVOLVED IN: transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase, subunit 2, domain 6 (InterPro:IPR007120), RNA polymerase Rpb2, domain 7 (InterPro:IPR007641), RNA polymerase, beta subunit, protrusion (InterPro:IPR007644), RNA polymerase Rpb2, domain 3 (InterPro:IPR007645), DNA-directed RNA polymerase, subunit 2 (InterPro:IPR015712), RNA polymerase Rpb2, domain 2 (InterPro:IPR007642), RNA polymerase Rpb2, domain 4 (InterPro:IPR007646), RNA polymerase Rpb2, domain 5 (InterPro:IPR007647), RNA polymerase, beta subunit, conserved site (InterPro:IPR007121); BEST Arabidopsis thaliana protein match is: DNA-directed RNA polymerase family protein (TAIR:AT4G21710.1); Has 31946 Blast hits to 25220 proteins in 8516 species: Archae - 496; Bacteria - 14545; Metazoa - 599; Fungi - 7189; Plants - 2320; Viruses - 240; Other Eukaryotes - 6557 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      18247149..18258197 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123882.5 → NP_199327.4  nuclear RNA polymerase C2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199327.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KD38, Q9FKF1
      UniProtKB/TrEMBL
      A0A178UEB4, A0A5S9YBQ6
      Conserved Domains (3) summary
      cd00653
      Location:45 → 1157
      RNA_pol_B_RPB2; RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase ...
      pfam04566
      Location:550 → 611
      RNA_pol_Rpb2_4; RNA polymerase Rpb2, domain 4
      pfam04567
      Location:632 → 683
      RNA_pol_Rpb2_5; RNA polymerase Rpb2, domain 5

    2. NM_001344590.1 → NP_001332060.1  nuclear RNA polymerase C2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KD38, Q9FKF1
      UniProtKB/TrEMBL
      A0A178UEB4, A0A5S9YBQ6
      Conserved Domains (3) summary
      cd00653
      Location:45 → 1157
      RNA_pol_B_RPB2; RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase ...
      pfam04566
      Location:550 → 611
      RNA_pol_Rpb2_4; RNA polymerase Rpb2, domain 4
      pfam04567
      Location:632 → 683
      RNA_pol_Rpb2_5; RNA polymerase Rpb2, domain 5

    3. NM_001344591.1 → NP_001332059.1  nuclear RNA polymerase C2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFS9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4KD38.1

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