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Conserved domains on  [gi|79529842|ref|NP_199327|]
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nuclear RNA polymerase C2 [Arabidopsis thaliana]

Protein Classification

DNA-directed RNA polymerase III subunit RPC2( domain architecture ID 10090006)

DNA-directed RNA polymerase III subunit RPC2 is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RNA_pol_B_RPB2 cd00653
RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. ...
45-1157 0e+00

RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase complex contains two related members of this family, in each case they are the two largest subunits.The clamp is a mobile structure that grips DNA during elongation.


:

Pssm-ID: 238353 [Multi-domain]  Cd Length: 866  Bit Score: 1105.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   45 LVKQHLDSFNYFINVGIHKIVKANSRITSTV-DPSIYLRFKKVRVGEPSIINVNTVENINPHMCRLADMTYAAPIFVNIE 123
Cdd:cd00653    1 LVKQQIDSFNYFLNVGLQEIVKSIPPITDTDdDGRLKLKFGDIYLGKPKVEEGGVTRKLTPNECRLRDLTYSAPLYVDIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  124 YVHGshgNKAKSAKDNVIIGRMPIMLRSCRCVLHGKDEEELARLGECPLDPGGYFIIKGTEKVLLIQEQLSKNRIIIDsD 203
Cdd:cd00653   81 LTVN---DKGKIKEQEVFIGEIPIMLRSKLCNLNGLTPEELIKLGECPLDPGGYFIINGTEKVIINQEQRSPNVIIVE-D 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  204 KKGNINASVTSSTEMTkSKTVIQMEKeKIYLFLHRFVKKIPIIIvlkamgmesdqeivqmvgrdprfsasllpsieecvs 283
Cdd:cd00653  157 SKGKRIYTKTSIPSYS-PYRGSWLEV-KSDKKKDRIYVRIDLKR------------------------------------ 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  284 egvntQKQALDYLEAKVkkisygtppekdgralsilrdlflahvpvpdnnfrqkcFYVGVMLRRMIEAMLNKDAMDDKDY 363
Cdd:cd00653  199 -----QEEALKYIGKRF--------------------------------------EDLIYMIRKLILLVLGKGKLDDIDH 235
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  364 VGNKRLELSGQLISLLFEDLFKTMLSEAIKNVDHILNKpirasRFDFSQCLNKDSRYsISLGLERTLSTGNFDIKRFRMH 443
Cdd:cd00653  236 LGNKRVRLAGELLQNLFRSGLKRLEREVKEKLQKQLSK-----KKDLTPQLLINSKP-ITSGIKEFLATGNWGSKRFLMQ 309
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  444 RKGMTQVLTRLSFIGSMGFITKIS-PQFEKSRKVSGPRSLQPSQWGMLCPCDTPEGESCGLVKNLALMTHVTtdeeegpl 522
Cdd:cd00653  310 RSGLSQVLDRLNPLSELSHKRRISsLGLFRERKGFEVRDLHPSHWGRICPIETPEGENCGLVKNLALMARIS-------- 381
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  523 vamcyklgvtdlevlsaeelhtpdsflvilnglilgkhsrpqyfanslrrlrragkigefvsvftnekqhcvyvasdvGR 602
Cdd:cd00653  382 ------------------------------------------------------------------------------GR 383
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  603 VCRPLVIADKgisrvkqhhmkelqdgvrtfddfirdglieyldvneennalialyesdgtteldegaeaakaDTTHIEIE 682
Cdd:cd00653  384 IERPYRIVEK--------------------------------------------------------------EVTHIEIS 401
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  683 PFTILGVVAGLIPYPHHNQSPRNTYQCAMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNAT 762
Cdd:cd00653  402 PSQILSVAASLIPFPEHNQSPRNLYQSNMQKQAVGTPALNQQYRMDTKLYLLLYPQKPLVGTGIEEYIAFGELPLGQNAI 481
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  763 VAVMSFSGYDIEDAIVMNKSSLDRGFGRCIVMKKIVAMSQKYDNCTADRILiPQRTGPDAEKMQILDDDGLATPGEIIRP 842
Cdd:cd00653  482 VAVMSYSGYNFEDAIIINKSSVDRGFFRSIHYKKYEIELRKTKNGPEEITR-GDIPNVSEEKLKNLDEDGIIRPGARVEP 560
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  843 NDIYINKQVPV-DTVTKFTSALSDSQYRPAREYFKGpeGETQVVDRVALCS---DKKGQLCIKYIIRHTRRPELGDKFSS 918
Cdd:cd00653  561 GDILVGKITPKgETESTPIFGEKARDVRDTSLKYPG--GEKGIVDDVKIFSrelNDGGNKLVKVYIRQKRKPQIGDKFAS 638
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  919 RHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFGErsghaDKVETISA 998
Cdd:cd00653  639 RHGQKGVISKILPQEDMPFTEDGIPPDIILNPHGFPSRMTIGQLLESLLGKAGALLGKFGDATPFDG-----AEEEDISE 713
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  999 TLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDC 1078
Cdd:cd00653  714 LLGEAGLNYYGKEVLYDGRTGEPLEAPIFVGPVYYQRLKHMVDDKIHARSTGPYSLLTRQPLKGRSRGGGQRFGEMERDA 793
                       1050      1060      1070      1080      1090      1100      1110
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79529842 1079 LIAYGASMLIYERLMISSDPFEVQVCRACGLLGYYNYklkkavCTTCKNGDNIATMKLPYACKLLFQELQSMNVVPRLK 1157
Cdd:cd00653  794 LIAHGAAYLLQERLTIKSDDVVARVCVKCGIILSANL------CRLCKKGTNISKVGIPYAFKLLFQELQSMNIDPRLK 866
RNA_pol_Rpb2_4 pfam04566
RNA polymerase Rpb2, domain 4; RNA polymerases catalyze the DNA dependent polymerization of ...
550-611 5.92e-25

RNA polymerase Rpb2, domain 4; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 4, is also known as the external 2 domain.


:

Pssm-ID: 428012 [Multi-domain]  Cd Length: 62  Bit Score: 98.59  E-value: 5.92e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 79529842    550 VILNGLILGKHSRPQYFANSLRRLRRAGKIGEFVSVFTNEKQHCVYVASDVGRVCRPLVIAD 611
Cdd:pfam04566    1 VFLNGNLIGVHRDPEELVETLRKLRRSGKISEEVSIVRDIREKEVRINTDGGRVCRPLIIVE 62
RNA_pol_Rpb2_5 pfam04567
RNA polymerase Rpb2, domain 5; RNA polymerases catalyze the DNA dependent polymerization of ...
632-683 1.12e-13

RNA polymerase Rpb2, domain 5; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 5, is also known as the external 2 domain.


:

Pssm-ID: 428013 [Multi-domain]  Cd Length: 53  Bit Score: 66.41  E-value: 1.12e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 79529842    632 FDDFIRDGLIEYLDVNEENNALIALYESDGTTELDEGAEAAKADT-THIEIEP 683
Cdd:pfam04567    1 WSDLLREGVIEYLDAEEEETSMIAMTPEDLEESSREEREGPYAHTyTHCEIHP 53
 
Name Accession Description Interval E-value
RNA_pol_B_RPB2 cd00653
RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. ...
45-1157 0e+00

RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase complex contains two related members of this family, in each case they are the two largest subunits.The clamp is a mobile structure that grips DNA during elongation.


Pssm-ID: 238353 [Multi-domain]  Cd Length: 866  Bit Score: 1105.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   45 LVKQHLDSFNYFINVGIHKIVKANSRITSTV-DPSIYLRFKKVRVGEPSIINVNTVENINPHMCRLADMTYAAPIFVNIE 123
Cdd:cd00653    1 LVKQQIDSFNYFLNVGLQEIVKSIPPITDTDdDGRLKLKFGDIYLGKPKVEEGGVTRKLTPNECRLRDLTYSAPLYVDIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  124 YVHGshgNKAKSAKDNVIIGRMPIMLRSCRCVLHGKDEEELARLGECPLDPGGYFIIKGTEKVLLIQEQLSKNRIIIDsD 203
Cdd:cd00653   81 LTVN---DKGKIKEQEVFIGEIPIMLRSKLCNLNGLTPEELIKLGECPLDPGGYFIINGTEKVIINQEQRSPNVIIVE-D 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  204 KKGNINASVTSSTEMTkSKTVIQMEKeKIYLFLHRFVKKIPIIIvlkamgmesdqeivqmvgrdprfsasllpsieecvs 283
Cdd:cd00653  157 SKGKRIYTKTSIPSYS-PYRGSWLEV-KSDKKKDRIYVRIDLKR------------------------------------ 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  284 egvntQKQALDYLEAKVkkisygtppekdgralsilrdlflahvpvpdnnfrqkcFYVGVMLRRMIEAMLNKDAMDDKDY 363
Cdd:cd00653  199 -----QEEALKYIGKRF--------------------------------------EDLIYMIRKLILLVLGKGKLDDIDH 235
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  364 VGNKRLELSGQLISLLFEDLFKTMLSEAIKNVDHILNKpirasRFDFSQCLNKDSRYsISLGLERTLSTGNFDIKRFRMH 443
Cdd:cd00653  236 LGNKRVRLAGELLQNLFRSGLKRLEREVKEKLQKQLSK-----KKDLTPQLLINSKP-ITSGIKEFLATGNWGSKRFLMQ 309
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  444 RKGMTQVLTRLSFIGSMGFITKIS-PQFEKSRKVSGPRSLQPSQWGMLCPCDTPEGESCGLVKNLALMTHVTtdeeegpl 522
Cdd:cd00653  310 RSGLSQVLDRLNPLSELSHKRRISsLGLFRERKGFEVRDLHPSHWGRICPIETPEGENCGLVKNLALMARIS-------- 381
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  523 vamcyklgvtdlevlsaeelhtpdsflvilnglilgkhsrpqyfanslrrlrragkigefvsvftnekqhcvyvasdvGR 602
Cdd:cd00653  382 ------------------------------------------------------------------------------GR 383
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  603 VCRPLVIADKgisrvkqhhmkelqdgvrtfddfirdglieyldvneennalialyesdgtteldegaeaakaDTTHIEIE 682
Cdd:cd00653  384 IERPYRIVEK--------------------------------------------------------------EVTHIEIS 401
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  683 PFTILGVVAGLIPYPHHNQSPRNTYQCAMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNAT 762
Cdd:cd00653  402 PSQILSVAASLIPFPEHNQSPRNLYQSNMQKQAVGTPALNQQYRMDTKLYLLLYPQKPLVGTGIEEYIAFGELPLGQNAI 481
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  763 VAVMSFSGYDIEDAIVMNKSSLDRGFGRCIVMKKIVAMSQKYDNCTADRILiPQRTGPDAEKMQILDDDGLATPGEIIRP 842
Cdd:cd00653  482 VAVMSYSGYNFEDAIIINKSSVDRGFFRSIHYKKYEIELRKTKNGPEEITR-GDIPNVSEEKLKNLDEDGIIRPGARVEP 560
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  843 NDIYINKQVPV-DTVTKFTSALSDSQYRPAREYFKGpeGETQVVDRVALCS---DKKGQLCIKYIIRHTRRPELGDKFSS 918
Cdd:cd00653  561 GDILVGKITPKgETESTPIFGEKARDVRDTSLKYPG--GEKGIVDDVKIFSrelNDGGNKLVKVYIRQKRKPQIGDKFAS 638
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  919 RHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFGErsghaDKVETISA 998
Cdd:cd00653  639 RHGQKGVISKILPQEDMPFTEDGIPPDIILNPHGFPSRMTIGQLLESLLGKAGALLGKFGDATPFDG-----AEEEDISE 713
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  999 TLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDC 1078
Cdd:cd00653  714 LLGEAGLNYYGKEVLYDGRTGEPLEAPIFVGPVYYQRLKHMVDDKIHARSTGPYSLLTRQPLKGRSRGGGQRFGEMERDA 793
                       1050      1060      1070      1080      1090      1100      1110
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79529842 1079 LIAYGASMLIYERLMISSDPFEVQVCRACGLLGYYNYklkkavCTTCKNGDNIATMKLPYACKLLFQELQSMNVVPRLK 1157
Cdd:cd00653  794 LIAHGAAYLLQERLTIKSDDVVARVCVKCGIILSANL------CRLCKKGTNISKVGIPYAFKLLFQELQSMNIDPRLK 866
PRK08565 PRK08565
DNA-directed RNA polymerase subunit B; Provisional
35-1160 0e+00

DNA-directed RNA polymerase subunit B; Provisional


Pssm-ID: 236291 [Multi-domain]  Cd Length: 1103  Bit Score: 1032.21  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    35 LVPEFLKVRGLVKQHLDSFNYFINVGIHKIVKANSRItSTVDPSIYLRFKKVRVGEPSIINVNTVEN-INPHMCRLADMT 113
Cdd:PRK08565    4 VVEAYFKEKGLVRQHLDSYNDFIERGLQEIVDEFGEI-KTEIPGLKIVLGKIRVGEPEIKEADGSERpITPMEARLRNLT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   114 YAAPIFVNIEYVHgshgNKAKSAKDNVIIGRMPIMLRSCRCVLHGKDEEELARLGECPLDPGGYFIIKGTEKVLLIQEQL 193
Cdd:PRK08565   83 YAAPLYLTMIPVE----NGIEYEPEEVKIGDLPIMVKSKICPLSGLSPDELIEIGEDPKDPGGYFIINGSERVIVSQEDL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   194 SKNRIIIDSDKKGNIN---ASVTSSTEMTKSKTVIQMEKEK-IYLFLHRFVKKIPIIIVLKAMGMESDQEIVQMVGRDPR 269
Cdd:PRK08565  159 APNRVLVDKGEAGSSIthtAKVISSRAGYRAQVTVERRKDGtIYVSFPAVPGKIPFVILMRALGLETDRDIVYAVSLDPE 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   270 FSASLLPSIEEcVSEGVNTQKQALDYLEakvKKISYGTP-PEKDGRALSILRDLFLAHVPVPDNNFRQKCFYVGVMLRRM 348
Cdd:PRK08565  239 IQQELLPSLEQ-ASSIAATVEDALDYIG---KRVAIGQPrEYRIERAEQILDKYLLPHLGTSPEDRIKKAYFLGQMASKL 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   349 IEAMLNKDAMDDKDYVGNKRLELSGQLISLLFEDLFKTMLSEAIKNVDHILNkpiRASRFDFSQCLNKDSrysISLGLER 428
Cdd:PRK08565  315 LELYLGRREPDDKDHYANKRLRLAGDLLAELFRVAFKQLVKDLKYQLEKSYA---RGRKLDLRAIVRPDI---ITERIRH 388
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   429 TLSTGNFDikrfrMHRKGMTQVLTRLSFIGSMGFITKI-------SPQFEKsrkvsgpRSLQPSQWGMLCPCDTPEGESC 501
Cdd:PRK08565  389 ALATGNWV-----GGRTGVSQLLDRTNYLSTLSHLRRVvsplsrgQPHFEA-------RDLHGTQWGRICPFETPEGPNC 456
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   502 GLVKNLALMTHVTTDEEEGPLVAMCYKLGVTDLEVLSAEElhTPDSFLVILNGLILGKHSRPQYFANSLRRLRRAGKIGE 581
Cdd:PRK08565  457 GLVKNLALMAQISVGVDEEEVEEILYELGVVPVEEAREEE--YISWSRVYLNGRLIGYHPDGEELAEKIRELRRSGKISD 534
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   582 FVSV------FTNEkqhcVYVASDVGRVCRPLVIADKGISRVKQHHMKELQDGVRTFDDFIRDGLIEYLDVNEENNALIA 655
Cdd:PRK08565  535 EVNVayietgEINE----VYVNCDSGRVRRPLIVVENGKPKLTREHVEKLKKGELTFDDLVKMGVIEYLDAEEEENAYVA 610
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   656 LYESDGTTEldegaeaakadTTHIEIEPFTILGVVAGLIPYPHHNQSPRNTYQCAMGKQAMGNIAYNQLNRMDTLLYLLV 735
Cdd:PRK08565  611 LDPEDLTPE-----------HTHLEIWPPAILGITASIIPYPEHNQSPRNTYQAAMAKQSLGLYAANFRIRTDTRGHLLH 679
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   736 YPQRPLLTTRTIELVGYDKLGAGQNATVAVMSFSGYDIEDAIVMNKSSLDRGFGRCIVMKKIVAMSQKYDNCTADRILIP 815
Cdd:PRK08565  680 YPQRPLVQTRALEIIGYNDRPAGQNAVVAVLSYTGYNIEDAIIMNKASIERGLARSTFFRTYETEERKYPGGQEDKIEIP 759
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   816 QRT-----GPDAEKMqiLDDDGLATPGEIIRPNDIYINKQVPVDTVTKFTSALSDSQYR-----PAREyfkgpeGETQVV 885
Cdd:PRK08565  760 EPNvrgyrGEEYYRK--LDEDGIVSPEVEVKGGDVLIGKTSPPRFLEELEELSLGLQERrdtsvTVRH------GEKGIV 831
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   886 DRVALCSDKKGQLCIKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIEL 965
Cdd:PRK08565  832 DTVLITESPEGNKLVKVRVRDLRIPELGDKFASRHGQKGVIGMLVPQEDMPFTEDGIVPDLIINPHAIPSRMTVGQLLES 911
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   966 LGSKAGVSCGRFHYGSAFgersgHADKVETISATLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMH 1045
Cdd:PRK08565  912 IAGKVAALEGRFVDATPF-----YGEPEEELRKELLKLGYKPDGTEVMYDGRTGEKIKAPIFIGVVYYQKLHHMVADKIH 986
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  1046 ARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSDPFEVQVCRACGLLGYYNYKLKKAVCTTC 1125
Cdd:PRK08565  987 ARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGHGAAMLLKERLLDSSDKTTIYVCELCGHIAWYDRRKNKYVCPIH 1066
                        1130      1140      1150
                  ....*....|....*....|....*....|....*
gi 79529842  1126 KNGDNIATMKLPYACKLLFQELQSMNVVPRLKLTE 1160
Cdd:PRK08565 1067 GDKGNISPVEVSYAFKLLLQELMSMGISPRLKLGD 1101
rpoB_arch TIGR03670
DNA-directed RNA polymerase subunit B; This model represents the archaeal version of ...
550-1161 0e+00

DNA-directed RNA polymerase subunit B; This model represents the archaeal version of DNA-directed RNA polymerase subunit B (rpoB) and is observed in all archaeal genomes.


Pssm-ID: 274713 [Multi-domain]  Cd Length: 599  Bit Score: 664.42  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    550 VILNGLILGKHSRPQYFANSLRRLRRAGKIGEFVSVFTNEKQHCVYVASDVGRVCRPLVIADKGISRVKQHHMKELQDGV 629
Cdd:TIGR03670    1 VYLNGRLIGYHDDPEELVEEVRKLRRSGKLSQEVNVAYYEETNEVYINCDAGRIRRPLIVVENGKPKLTREHVEKLKEGE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    630 RTFDDFIRDGLIEYLDVNEENNALIALYESDGTTEldegaeaakadTTHIEIEPFTILGVVAGLIPYPHHNQSPRNTYQC 709
Cdd:TIGR03670   81 LTWDDLVKQGVIEYLDAEEEENAYIALDPEELTPE-----------HTHLEIDPSAILGIIASTIPYPEHNQSPRNTMGA 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    710 AMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNATVAVMSFSGYDIEDAIVMNKSSLDRGFG 789
Cdd:TIGR03670  150 AMAKQSLGLYAANYRIRLDTRGHLLHYPQKPLVKTRVLELIGYDDRPAGQNFVVAVMSYEGYNIEDALIMNKASIERGLA 229
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    790 RCIVMKKIVAMSQKYDNCTADRILIPQRT-----GPDAEKMqiLDDDGLATPGEIIRPNDIYINKQVPVDTVTKFTSALS 864
Cdd:TIGR03670  230 RSTFFRTYEAEERRYPGGQEDRFEIPEPDvrgyrGEEAYKH--LDEDGIVYPEVEVKGGDVLIGKTSPPRFLEELREFGL 307
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    865 DSQYR-----PAREyfkgpeGETQVVDRVALCSDKKGQLCIKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSE 939
Cdd:TIGR03670  308 VTERRrdtsvTVRH------GEKGIVDKVIITETEEGNKLVKVRVRDLRIPELGDKFASRHGQKGVIGMIVPQEDMPFTE 381
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    940 LGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFGErsghaDKVETISATLVEKGFSYSGKDLLYSGISG 1019
Cdd:TIGR03670  382 DGIVPDLIINPHAIPSRMTVGQLLEMIAGKVAALEGRRVDGTPFEG-----EPEEELRKELLKLGFKPDGKEVMYDGITG 456
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   1020 EPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSDPF 1099
Cdd:TIGR03670  457 EKLEAEIFIGVIYYQKLHHMVADKIHARSRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIGHGAAMLLKERLLDESDKY 536
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 79529842   1100 EVQVCRACGLLGYYNYKLKKAVCTTCKNGDNIATMKLPYACKLLFQELQSMNVVPRLKLTEA 1161
Cdd:TIGR03670  537 VVYVCENCGHIAWEDKRKGTAYCPVCGETGDISPVEMSYAFKLLLDELKSLGISPRLELGDK 598
RpoB COG0085
DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA ...
33-1160 0e+00

DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA polymerase, beta subunit/140 kD subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 439855 [Multi-domain]  Cd Length: 1001  Bit Score: 622.90  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   33 FQLVPEFLKVRGLVKQHLDSFNYFINVGIHKIVKANSRITsTVDPSIYLRFKKVRVGEPSIinvnTVENinphmCRLADM 112
Cdd:COG0085    4 FAKIKEPLELPNLLEIQLDSFNWFLEEGLQEIFDEISPIE-DFTGNLSLEFGDYRLGEPKY----TPEE-----CKERDL 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  113 TYAAPIFVNIEYVHGSHGnKAKSakDNVIIGRMPIMLRScrcvlhgkdeeelarlgecpldpgGYFIIKGTEKVLLIQEQ 192
Cdd:COG0085   74 TYAAPLYVKVRLVNKETG-EIKE--QEVFMGDFPLMTDS------------------------GTFIINGTERVIVSQLV 126
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  193 LSKNRIIIDSDKKGN---INASVTSS----TEMTKSKtviqmeKEKIYLFLHRfVKKIPIIIVLKAMGMESDQEIVQMVG 265
Cdd:COG0085  127 RSPGVYFVEEEDKSGkdlYSAKVIPSrgawLEFETDK------DGTIYVRIDR-KRKIPVTVLLRALGLETDEEILEAFG 199
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  266 RDPRFSaSLLPSIEEcvsEGVNTQKQALDYLEakvKKISYGTPPEKDgRALSILRDLF-------LAHV----------- 327
Cdd:COG0085  200 DDPIQE-YILATLEK---DNTKTQEEALLEIY---RKLRPGEPPTIE-RAEQLLDNLFfdpkrydLAHVgrykinkklgl 271
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  328 PVPDNNFRQKCFYVGVMLRRMIEAMLNKDAMDDKDYVGNKRLELSGQLIsllfEDLFKTMLSEAIKNVdhilnkpirasr 407
Cdd:COG0085  272 DVPPEDRVLTAEDIVATIKYLLELHLGEREPDDIDHLGNRRVRLVGELL----QNQFRVGLSRMERVV------------ 335
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  408 fdfsqclnkdsRYSISLGLERTLSTG---NFD-----IKRFrMHRKGMTQV---------LT---RLSFIGSMGfITKIS 467
Cdd:COG0085  336 -----------RERMTTQDVEAITPQsliNIRpvvaaIKEF-FGSSQLSQFmdqtnplseLThkrRLSALGPGG-LSRER 402
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  468 PQFEksrkVsgpRSLQPSQWGMLCPCDTPEGESCGLVKNLALMTHVttdeeegplvamcyklgvtdlevlsaeelhtpds 547
Cdd:COG0085  403 AGFE----V---RDVHPSHYGRMCPIETPEGPNIGLIGSLALYARV---------------------------------- 441
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  548 flvilnglilgkhsrpqyfanslrrlrragkigefvsvftnekqhcvyvaSDVGRVCRPLViadkgisRVKqhhmkelqD 627
Cdd:COG0085  442 --------------------------------------------------NEYGFIETPYR-------KVE--------N 456
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  628 GVRTFDdfirdglIEYLDVNEENNALIALYESDGTTE------------LDEGAEAAKADTTHIEIEPFTILGVVAGLIP 695
Cdd:COG0085  457 GKVTDE-------IEYLTADEEENYYIAQANAPLDEDgnfleervlvryRGEEVLVPPEEVDYMDVSPKQIVSVATSLIP 529
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  696 YPHHNQSPRNTYQCAMGKQAMGNIAYNqlnrMDTLLYLLV----------YPQRPLltTRTIELVG------------YD 753
Cdd:COG0085  530 FLEHDDANRALMGANMQRQAVPLLRPE----APLLHYPLQkfqrsnqgtcINQRPI--VRVGDRVEkgdvladgpatdNG 603
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  754 KLGAGQNATVAVMSFSGYDIEDAIVMNKSSLDRGFGRCIVMKKIVAMSQKY-----DNcTADrilIPQrTGPDAEKMqiL 828
Cdd:COG0085  604 ELALGQNLLVAFMPWEGYNYEDAIIISERLVKDDVLTSIHIEEYEIEARDTklgpeEI-TRD---IPN-VSEEALRN--L 676
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  829 DDDGLATPGEIIRPNDIYINKqvpvdtVT--KFTSaLSdSQYRPAREYF--KGPE----------GETQVVDRVALCSDK 894
Cdd:COG0085  677 DEDGIIRIGAEVKGGDILVGK------VTpkGETE-LT-PEERLLRAIFgeKAREvrdtslrvphGEKGKVIDVKVFSRE 748
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  895 KG--------QLcIKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELL 966
Cdd:COG0085  749 EGdelppgvnKL-VRVYVAQKRKIEVGDKLAGRHGNKGVISRILPQEDMPFLEDGTPVDIVLNPLGVPSRMNVGQVLETH 827
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  967 GSKAGVSCGRFHYGSAF-GErsghadKVETISATLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMH 1045
Cdd:COG0085  828 LGWAAALLGRRVATPVFdGA------PEEEIRELLEKAGLPPDGKEVLYDGRTGEPFDNPVTVGYMYYLKLHHMVDDKIH 901
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842 1046 ARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSDpfevqvcRACGLLGYYNYKLKkavcttc 1125
Cdd:COG0085  902 ARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQERLTIKSD-------DVCGRVKVYEAIVK------- 967
                       1210      1220      1230
                 ....*....|....*....|....*....|....*
gi 79529842 1126 knGDNIATMKLPYACKLLFQELQSMNVVPRLKLTE 1160
Cdd:COG0085  968 --GENIPEPGIPESFKVLLKELQSLGLDVEVLSED 1000
RNA_pol_Rpb2_6 pfam00562
RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of ...
690-1065 0e+00

RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain represents the hybrid binding domain and the wall domain. The hybrid binding domain binds the nascent RNA strand / template DNA strand in the Pol II transcription elongation complex. This domain contains the important structural motifs, switch 3 and the flap loop and binds an active site metal ion. This domain is also involved in binding to Rpb1 and Rpb3. Many of the bacterial members contain large insertions within this domain, as region known as dispensable region 2 (DRII).


Pssm-ID: 459854 [Multi-domain]  Cd Length: 371  Bit Score: 535.19  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    690 VAGLIPYPHHNQSPRNTYQCAMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNATVAVMSFS 769
Cdd:pfam00562    1 VASLIPFVDHNQSPRNTYQCAMGKQAMGIYTLNKFYRSDQNTYVLCYPQKPLVKTGAVEAGGFGELPLGQNAIVAVMSYT 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    770 GYDIEDAIVMNKSSLDRGFGRCIVMKKIVAmsQKYDNCTADRILIPQRTGPDaEKMQILDDDGLATPGEIIRPNDIYINK 849
Cdd:pfam00562   81 GYNQEDAIIINKSSVDRGFFTSIHIKEIEA--RKTKLGPIEEITRDIPNVSE-EALKKLDEDGIVRVGAEVKPGDILVGK 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    850 QVPVDTVTKFTSALSDSQYRPAREYFKGPEGETQVVDRVALCS-DKKGQLCIKYIIRHTRRPELGDKFSSRHGQKGVCGI 928
Cdd:pfam00562  158 VGPTELTKLLRAIFGEKARDVKDTSLKVPPGEEGVVDDVIVFElPPGGIKMVKVYIRQKRKPEVGDKFASRHGQKGVVSR 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    929 IIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFGERSghaDKVETISATLVEKGFSYS 1008
Cdd:pfam00562  238 ILPQEDMPFTEDGIPPDIILNPHGVPSRMTIGQLLETHLGKAAALLGVFVDATPFDGAS---TEVEDIGELLEKAGYNYY 314
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 79529842   1009 GKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSK 1065
Cdd:pfam00562  315 GKEVLYDGRTGEPFEAPIFVGPIYYQKLKHMVDDKIHARSTGPYSLLTRQPLGGRAR 371
RNA_pol_Rpb2_4 pfam04566
RNA polymerase Rpb2, domain 4; RNA polymerases catalyze the DNA dependent polymerization of ...
550-611 5.92e-25

RNA polymerase Rpb2, domain 4; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 4, is also known as the external 2 domain.


Pssm-ID: 428012 [Multi-domain]  Cd Length: 62  Bit Score: 98.59  E-value: 5.92e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 79529842    550 VILNGLILGKHSRPQYFANSLRRLRRAGKIGEFVSVFTNEKQHCVYVASDVGRVCRPLVIAD 611
Cdd:pfam04566    1 VFLNGNLIGVHRDPEELVETLRKLRRSGKISEEVSIVRDIREKEVRINTDGGRVCRPLIIVE 62
RNA_pol_Rpb2_5 pfam04567
RNA polymerase Rpb2, domain 5; RNA polymerases catalyze the DNA dependent polymerization of ...
632-683 1.12e-13

RNA polymerase Rpb2, domain 5; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 5, is also known as the external 2 domain.


Pssm-ID: 428013 [Multi-domain]  Cd Length: 53  Bit Score: 66.41  E-value: 1.12e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 79529842    632 FDDFIRDGLIEYLDVNEENNALIALYESDGTTELDEGAEAAKADT-THIEIEP 683
Cdd:pfam04567    1 WSDLLREGVIEYLDAEEEETSMIAMTPEDLEESSREEREGPYAHTyTHCEIHP 53
 
Name Accession Description Interval E-value
RNA_pol_B_RPB2 cd00653
RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. ...
45-1157 0e+00

RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase complex contains two related members of this family, in each case they are the two largest subunits.The clamp is a mobile structure that grips DNA during elongation.


Pssm-ID: 238353 [Multi-domain]  Cd Length: 866  Bit Score: 1105.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   45 LVKQHLDSFNYFINVGIHKIVKANSRITSTV-DPSIYLRFKKVRVGEPSIINVNTVENINPHMCRLADMTYAAPIFVNIE 123
Cdd:cd00653    1 LVKQQIDSFNYFLNVGLQEIVKSIPPITDTDdDGRLKLKFGDIYLGKPKVEEGGVTRKLTPNECRLRDLTYSAPLYVDIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  124 YVHGshgNKAKSAKDNVIIGRMPIMLRSCRCVLHGKDEEELARLGECPLDPGGYFIIKGTEKVLLIQEQLSKNRIIIDsD 203
Cdd:cd00653   81 LTVN---DKGKIKEQEVFIGEIPIMLRSKLCNLNGLTPEELIKLGECPLDPGGYFIINGTEKVIINQEQRSPNVIIVE-D 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  204 KKGNINASVTSSTEMTkSKTVIQMEKeKIYLFLHRFVKKIPIIIvlkamgmesdqeivqmvgrdprfsasllpsieecvs 283
Cdd:cd00653  157 SKGKRIYTKTSIPSYS-PYRGSWLEV-KSDKKKDRIYVRIDLKR------------------------------------ 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  284 egvntQKQALDYLEAKVkkisygtppekdgralsilrdlflahvpvpdnnfrqkcFYVGVMLRRMIEAMLNKDAMDDKDY 363
Cdd:cd00653  199 -----QEEALKYIGKRF--------------------------------------EDLIYMIRKLILLVLGKGKLDDIDH 235
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  364 VGNKRLELSGQLISLLFEDLFKTMLSEAIKNVDHILNKpirasRFDFSQCLNKDSRYsISLGLERTLSTGNFDIKRFRMH 443
Cdd:cd00653  236 LGNKRVRLAGELLQNLFRSGLKRLEREVKEKLQKQLSK-----KKDLTPQLLINSKP-ITSGIKEFLATGNWGSKRFLMQ 309
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  444 RKGMTQVLTRLSFIGSMGFITKIS-PQFEKSRKVSGPRSLQPSQWGMLCPCDTPEGESCGLVKNLALMTHVTtdeeegpl 522
Cdd:cd00653  310 RSGLSQVLDRLNPLSELSHKRRISsLGLFRERKGFEVRDLHPSHWGRICPIETPEGENCGLVKNLALMARIS-------- 381
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  523 vamcyklgvtdlevlsaeelhtpdsflvilnglilgkhsrpqyfanslrrlrragkigefvsvftnekqhcvyvasdvGR 602
Cdd:cd00653  382 ------------------------------------------------------------------------------GR 383
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  603 VCRPLVIADKgisrvkqhhmkelqdgvrtfddfirdglieyldvneennalialyesdgtteldegaeaakaDTTHIEIE 682
Cdd:cd00653  384 IERPYRIVEK--------------------------------------------------------------EVTHIEIS 401
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  683 PFTILGVVAGLIPYPHHNQSPRNTYQCAMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNAT 762
Cdd:cd00653  402 PSQILSVAASLIPFPEHNQSPRNLYQSNMQKQAVGTPALNQQYRMDTKLYLLLYPQKPLVGTGIEEYIAFGELPLGQNAI 481
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  763 VAVMSFSGYDIEDAIVMNKSSLDRGFGRCIVMKKIVAMSQKYDNCTADRILiPQRTGPDAEKMQILDDDGLATPGEIIRP 842
Cdd:cd00653  482 VAVMSYSGYNFEDAIIINKSSVDRGFFRSIHYKKYEIELRKTKNGPEEITR-GDIPNVSEEKLKNLDEDGIIRPGARVEP 560
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  843 NDIYINKQVPV-DTVTKFTSALSDSQYRPAREYFKGpeGETQVVDRVALCS---DKKGQLCIKYIIRHTRRPELGDKFSS 918
Cdd:cd00653  561 GDILVGKITPKgETESTPIFGEKARDVRDTSLKYPG--GEKGIVDDVKIFSrelNDGGNKLVKVYIRQKRKPQIGDKFAS 638
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  919 RHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFGErsghaDKVETISA 998
Cdd:cd00653  639 RHGQKGVISKILPQEDMPFTEDGIPPDIILNPHGFPSRMTIGQLLESLLGKAGALLGKFGDATPFDG-----AEEEDISE 713
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  999 TLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDC 1078
Cdd:cd00653  714 LLGEAGLNYYGKEVLYDGRTGEPLEAPIFVGPVYYQRLKHMVDDKIHARSTGPYSLLTRQPLKGRSRGGGQRFGEMERDA 793
                       1050      1060      1070      1080      1090      1100      1110
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79529842 1079 LIAYGASMLIYERLMISSDPFEVQVCRACGLLGYYNYklkkavCTTCKNGDNIATMKLPYACKLLFQELQSMNVVPRLK 1157
Cdd:cd00653  794 LIAHGAAYLLQERLTIKSDDVVARVCVKCGIILSANL------CRLCKKGTNISKVGIPYAFKLLFQELQSMNIDPRLK 866
PRK08565 PRK08565
DNA-directed RNA polymerase subunit B; Provisional
35-1160 0e+00

DNA-directed RNA polymerase subunit B; Provisional


Pssm-ID: 236291 [Multi-domain]  Cd Length: 1103  Bit Score: 1032.21  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    35 LVPEFLKVRGLVKQHLDSFNYFINVGIHKIVKANSRItSTVDPSIYLRFKKVRVGEPSIINVNTVEN-INPHMCRLADMT 113
Cdd:PRK08565    4 VVEAYFKEKGLVRQHLDSYNDFIERGLQEIVDEFGEI-KTEIPGLKIVLGKIRVGEPEIKEADGSERpITPMEARLRNLT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   114 YAAPIFVNIEYVHgshgNKAKSAKDNVIIGRMPIMLRSCRCVLHGKDEEELARLGECPLDPGGYFIIKGTEKVLLIQEQL 193
Cdd:PRK08565   83 YAAPLYLTMIPVE----NGIEYEPEEVKIGDLPIMVKSKICPLSGLSPDELIEIGEDPKDPGGYFIINGSERVIVSQEDL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   194 SKNRIIIDSDKKGNIN---ASVTSSTEMTKSKTVIQMEKEK-IYLFLHRFVKKIPIIIVLKAMGMESDQEIVQMVGRDPR 269
Cdd:PRK08565  159 APNRVLVDKGEAGSSIthtAKVISSRAGYRAQVTVERRKDGtIYVSFPAVPGKIPFVILMRALGLETDRDIVYAVSLDPE 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   270 FSASLLPSIEEcVSEGVNTQKQALDYLEakvKKISYGTP-PEKDGRALSILRDLFLAHVPVPDNNFRQKCFYVGVMLRRM 348
Cdd:PRK08565  239 IQQELLPSLEQ-ASSIAATVEDALDYIG---KRVAIGQPrEYRIERAEQILDKYLLPHLGTSPEDRIKKAYFLGQMASKL 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   349 IEAMLNKDAMDDKDYVGNKRLELSGQLISLLFEDLFKTMLSEAIKNVDHILNkpiRASRFDFSQCLNKDSrysISLGLER 428
Cdd:PRK08565  315 LELYLGRREPDDKDHYANKRLRLAGDLLAELFRVAFKQLVKDLKYQLEKSYA---RGRKLDLRAIVRPDI---ITERIRH 388
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   429 TLSTGNFDikrfrMHRKGMTQVLTRLSFIGSMGFITKI-------SPQFEKsrkvsgpRSLQPSQWGMLCPCDTPEGESC 501
Cdd:PRK08565  389 ALATGNWV-----GGRTGVSQLLDRTNYLSTLSHLRRVvsplsrgQPHFEA-------RDLHGTQWGRICPFETPEGPNC 456
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   502 GLVKNLALMTHVTTDEEEGPLVAMCYKLGVTDLEVLSAEElhTPDSFLVILNGLILGKHSRPQYFANSLRRLRRAGKIGE 581
Cdd:PRK08565  457 GLVKNLALMAQISVGVDEEEVEEILYELGVVPVEEAREEE--YISWSRVYLNGRLIGYHPDGEELAEKIRELRRSGKISD 534
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   582 FVSV------FTNEkqhcVYVASDVGRVCRPLVIADKGISRVKQHHMKELQDGVRTFDDFIRDGLIEYLDVNEENNALIA 655
Cdd:PRK08565  535 EVNVayietgEINE----VYVNCDSGRVRRPLIVVENGKPKLTREHVEKLKKGELTFDDLVKMGVIEYLDAEEEENAYVA 610
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   656 LYESDGTTEldegaeaakadTTHIEIEPFTILGVVAGLIPYPHHNQSPRNTYQCAMGKQAMGNIAYNQLNRMDTLLYLLV 735
Cdd:PRK08565  611 LDPEDLTPE-----------HTHLEIWPPAILGITASIIPYPEHNQSPRNTYQAAMAKQSLGLYAANFRIRTDTRGHLLH 679
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   736 YPQRPLLTTRTIELVGYDKLGAGQNATVAVMSFSGYDIEDAIVMNKSSLDRGFGRCIVMKKIVAMSQKYDNCTADRILIP 815
Cdd:PRK08565  680 YPQRPLVQTRALEIIGYNDRPAGQNAVVAVLSYTGYNIEDAIIMNKASIERGLARSTFFRTYETEERKYPGGQEDKIEIP 759
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   816 QRT-----GPDAEKMqiLDDDGLATPGEIIRPNDIYINKQVPVDTVTKFTSALSDSQYR-----PAREyfkgpeGETQVV 885
Cdd:PRK08565  760 EPNvrgyrGEEYYRK--LDEDGIVSPEVEVKGGDVLIGKTSPPRFLEELEELSLGLQERrdtsvTVRH------GEKGIV 831
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   886 DRVALCSDKKGQLCIKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIEL 965
Cdd:PRK08565  832 DTVLITESPEGNKLVKVRVRDLRIPELGDKFASRHGQKGVIGMLVPQEDMPFTEDGIVPDLIINPHAIPSRMTVGQLLES 911
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   966 LGSKAGVSCGRFHYGSAFgersgHADKVETISATLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMH 1045
Cdd:PRK08565  912 IAGKVAALEGRFVDATPF-----YGEPEEELRKELLKLGYKPDGTEVMYDGRTGEKIKAPIFIGVVYYQKLHHMVADKIH 986
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  1046 ARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSDPFEVQVCRACGLLGYYNYKLKKAVCTTC 1125
Cdd:PRK08565  987 ARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGHGAAMLLKERLLDSSDKTTIYVCELCGHIAWYDRRKNKYVCPIH 1066
                        1130      1140      1150
                  ....*....|....*....|....*....|....*
gi 79529842  1126 KNGDNIATMKLPYACKLLFQELQSMNVVPRLKLTE 1160
Cdd:PRK08565 1067 GDKGNISPVEVSYAFKLLLQELMSMGISPRLKLGD 1101
rpoB_arch TIGR03670
DNA-directed RNA polymerase subunit B; This model represents the archaeal version of ...
550-1161 0e+00

DNA-directed RNA polymerase subunit B; This model represents the archaeal version of DNA-directed RNA polymerase subunit B (rpoB) and is observed in all archaeal genomes.


Pssm-ID: 274713 [Multi-domain]  Cd Length: 599  Bit Score: 664.42  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    550 VILNGLILGKHSRPQYFANSLRRLRRAGKIGEFVSVFTNEKQHCVYVASDVGRVCRPLVIADKGISRVKQHHMKELQDGV 629
Cdd:TIGR03670    1 VYLNGRLIGYHDDPEELVEEVRKLRRSGKLSQEVNVAYYEETNEVYINCDAGRIRRPLIVVENGKPKLTREHVEKLKEGE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    630 RTFDDFIRDGLIEYLDVNEENNALIALYESDGTTEldegaeaakadTTHIEIEPFTILGVVAGLIPYPHHNQSPRNTYQC 709
Cdd:TIGR03670   81 LTWDDLVKQGVIEYLDAEEEENAYIALDPEELTPE-----------HTHLEIDPSAILGIIASTIPYPEHNQSPRNTMGA 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    710 AMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNATVAVMSFSGYDIEDAIVMNKSSLDRGFG 789
Cdd:TIGR03670  150 AMAKQSLGLYAANYRIRLDTRGHLLHYPQKPLVKTRVLELIGYDDRPAGQNFVVAVMSYEGYNIEDALIMNKASIERGLA 229
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    790 RCIVMKKIVAMSQKYDNCTADRILIPQRT-----GPDAEKMqiLDDDGLATPGEIIRPNDIYINKQVPVDTVTKFTSALS 864
Cdd:TIGR03670  230 RSTFFRTYEAEERRYPGGQEDRFEIPEPDvrgyrGEEAYKH--LDEDGIVYPEVEVKGGDVLIGKTSPPRFLEELREFGL 307
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    865 DSQYR-----PAREyfkgpeGETQVVDRVALCSDKKGQLCIKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSE 939
Cdd:TIGR03670  308 VTERRrdtsvTVRH------GEKGIVDKVIITETEEGNKLVKVRVRDLRIPELGDKFASRHGQKGVIGMIVPQEDMPFTE 381
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    940 LGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFGErsghaDKVETISATLVEKGFSYSGKDLLYSGISG 1019
Cdd:TIGR03670  382 DGIVPDLIINPHAIPSRMTVGQLLEMIAGKVAALEGRRVDGTPFEG-----EPEEELRKELLKLGFKPDGKEVMYDGITG 456
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   1020 EPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSDPF 1099
Cdd:TIGR03670  457 EKLEAEIFIGVIYYQKLHHMVADKIHARSRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIGHGAAMLLKERLLDESDKY 536
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 79529842   1100 EVQVCRACGLLGYYNYKLKKAVCTTCKNGDNIATMKLPYACKLLFQELQSMNVVPRLKLTEA 1161
Cdd:TIGR03670  537 VVYVCENCGHIAWEDKRKGTAYCPVCGETGDISPVEMSYAFKLLLDELKSLGISPRLELGDK 598
PRK07225 PRK07225
DNA-directed RNA polymerase subunit B'; Validated
550-1161 0e+00

DNA-directed RNA polymerase subunit B'; Validated


Pssm-ID: 235972 [Multi-domain]  Cd Length: 605  Bit Score: 654.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   550 VILNGLILGKHSRPQYFANSLRRLRRAGKIGEFVSVFTNEKQHCVYVASDVGRVCRPLVIADKGISRVKQHHMKELQDGV 629
Cdd:PRK07225    7 VYVNGKLIGTHDDPEELVEEIREARRSGEISEEVNVSYKEETNEVIINTDAGRARRPLIVVENGEPLLTEEHIEKLKNGE 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   630 RTFDDFIRDGLIEYLDVNEENNALIALYESDGTTEldegaeaakadTTHIEIEPFTILGVVAGLIPYPHHNQSPRNTYQC 709
Cdd:PRK07225   87 LTFDDLVKQGVIEYLDAEEEENAYIAVYEEDLTEE-----------HTHLEIDPSLILGIGAGMIPYPEHNASPRITMGA 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   710 AMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNATVAVMSFSGYDIEDAIVMNKSSLDRGFG 789
Cdd:PRK07225  156 GMIKQSLGLPAANYKLRPDTRGHLLHYPQVPLVKTQTQEIIGFDERPAGQNFVVAVMSYEGYNIEDALIMNKASIERGLG 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   790 RCIVMKKIVAMSQKYDNCTADRILIPQ---RTGPDAEKMQILDDDGLATPGEIIRPNDIYINKQVPVDTVTKFTSALSDS 866
Cdd:PRK07225  236 RSHFFRTYEGEERRYPGGQEDRFEIPDkdvRGYRGEEAYRHLDEDGLVNPETEVKEGDVLIGKTSPPRFLEEPDDFGISP 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   867 QYRpaREY-FKGPEGETQVVDRVALCSDKKGQLCIKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPD 945
Cdd:PRK07225  316 EKR--RETsVTMRSGEEGIVDTVILTETEEGSRLVKVRVRDLRIPELGDKFASRHGQKGVIGLIVPQEDMPFTESGVVPD 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   946 LIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFgersgHADKVETISATLVEKGFSYSGKDLLYSGISGEPVEAY 1025
Cdd:PRK07225  394 LIINPHAIPSRMTVGHVLEMIGGKVGSLEGRRVDGTAF-----SGEDEEDLREALEKLGFEHTGKEVMYDGITGEKIEAE 468
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  1026 IFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSDPFEVQVCR 1105
Cdd:PRK07225  469 IFVGVIYYQKLHHMVANKLHARSRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIGHGAAMLLKERLLDESDKVEIYVCA 548
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 79529842  1106 ACGLLGYYNYKLKKAVCTTCKNGDNIATMKLPYACKLLFQELQSMNVVPRLKLTEA 1161
Cdd:PRK07225  549 KCGMIAIYDKKRNRKYCPICGEETDIYPVEMSYAFKLLLDELKSLGIAPRLELEDK 604
RpoB COG0085
DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA ...
33-1160 0e+00

DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA polymerase, beta subunit/140 kD subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 439855 [Multi-domain]  Cd Length: 1001  Bit Score: 622.90  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   33 FQLVPEFLKVRGLVKQHLDSFNYFINVGIHKIVKANSRITsTVDPSIYLRFKKVRVGEPSIinvnTVENinphmCRLADM 112
Cdd:COG0085    4 FAKIKEPLELPNLLEIQLDSFNWFLEEGLQEIFDEISPIE-DFTGNLSLEFGDYRLGEPKY----TPEE-----CKERDL 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  113 TYAAPIFVNIEYVHGSHGnKAKSakDNVIIGRMPIMLRScrcvlhgkdeeelarlgecpldpgGYFIIKGTEKVLLIQEQ 192
Cdd:COG0085   74 TYAAPLYVKVRLVNKETG-EIKE--QEVFMGDFPLMTDS------------------------GTFIINGTERVIVSQLV 126
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  193 LSKNRIIIDSDKKGN---INASVTSS----TEMTKSKtviqmeKEKIYLFLHRfVKKIPIIIVLKAMGMESDQEIVQMVG 265
Cdd:COG0085  127 RSPGVYFVEEEDKSGkdlYSAKVIPSrgawLEFETDK------DGTIYVRIDR-KRKIPVTVLLRALGLETDEEILEAFG 199
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  266 RDPRFSaSLLPSIEEcvsEGVNTQKQALDYLEakvKKISYGTPPEKDgRALSILRDLF-------LAHV----------- 327
Cdd:COG0085  200 DDPIQE-YILATLEK---DNTKTQEEALLEIY---RKLRPGEPPTIE-RAEQLLDNLFfdpkrydLAHVgrykinkklgl 271
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  328 PVPDNNFRQKCFYVGVMLRRMIEAMLNKDAMDDKDYVGNKRLELSGQLIsllfEDLFKTMLSEAIKNVdhilnkpirasr 407
Cdd:COG0085  272 DVPPEDRVLTAEDIVATIKYLLELHLGEREPDDIDHLGNRRVRLVGELL----QNQFRVGLSRMERVV------------ 335
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  408 fdfsqclnkdsRYSISLGLERTLSTG---NFD-----IKRFrMHRKGMTQV---------LT---RLSFIGSMGfITKIS 467
Cdd:COG0085  336 -----------RERMTTQDVEAITPQsliNIRpvvaaIKEF-FGSSQLSQFmdqtnplseLThkrRLSALGPGG-LSRER 402
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  468 PQFEksrkVsgpRSLQPSQWGMLCPCDTPEGESCGLVKNLALMTHVttdeeegplvamcyklgvtdlevlsaeelhtpds 547
Cdd:COG0085  403 AGFE----V---RDVHPSHYGRMCPIETPEGPNIGLIGSLALYARV---------------------------------- 441
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  548 flvilnglilgkhsrpqyfanslrrlrragkigefvsvftnekqhcvyvaSDVGRVCRPLViadkgisRVKqhhmkelqD 627
Cdd:COG0085  442 --------------------------------------------------NEYGFIETPYR-------KVE--------N 456
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  628 GVRTFDdfirdglIEYLDVNEENNALIALYESDGTTE------------LDEGAEAAKADTTHIEIEPFTILGVVAGLIP 695
Cdd:COG0085  457 GKVTDE-------IEYLTADEEENYYIAQANAPLDEDgnfleervlvryRGEEVLVPPEEVDYMDVSPKQIVSVATSLIP 529
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  696 YPHHNQSPRNTYQCAMGKQAMGNIAYNqlnrMDTLLYLLV----------YPQRPLltTRTIELVG------------YD 753
Cdd:COG0085  530 FLEHDDANRALMGANMQRQAVPLLRPE----APLLHYPLQkfqrsnqgtcINQRPI--VRVGDRVEkgdvladgpatdNG 603
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  754 KLGAGQNATVAVMSFSGYDIEDAIVMNKSSLDRGFGRCIVMKKIVAMSQKY-----DNcTADrilIPQrTGPDAEKMqiL 828
Cdd:COG0085  604 ELALGQNLLVAFMPWEGYNYEDAIIISERLVKDDVLTSIHIEEYEIEARDTklgpeEI-TRD---IPN-VSEEALRN--L 676
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  829 DDDGLATPGEIIRPNDIYINKqvpvdtVT--KFTSaLSdSQYRPAREYF--KGPE----------GETQVVDRVALCSDK 894
Cdd:COG0085  677 DEDGIIRIGAEVKGGDILVGK------VTpkGETE-LT-PEERLLRAIFgeKAREvrdtslrvphGEKGKVIDVKVFSRE 748
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  895 KG--------QLcIKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELL 966
Cdd:COG0085  749 EGdelppgvnKL-VRVYVAQKRKIEVGDKLAGRHGNKGVISRILPQEDMPFLEDGTPVDIVLNPLGVPSRMNVGQVLETH 827
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  967 GSKAGVSCGRFHYGSAF-GErsghadKVETISATLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMH 1045
Cdd:COG0085  828 LGWAAALLGRRVATPVFdGA------PEEEIRELLEKAGLPPDGKEVLYDGRTGEPFDNPVTVGYMYYLKLHHMVDDKIH 901
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842 1046 ARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSDpfevqvcRACGLLGYYNYKLKkavcttc 1125
Cdd:COG0085  902 ARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQERLTIKSD-------DVCGRVKVYEAIVK------- 967
                       1210      1220      1230
                 ....*....|....*....|....*....|....*
gi 79529842 1126 knGDNIATMKLPYACKLLFQELQSMNVVPRLKLTE 1160
Cdd:COG0085  968 --GENIPEPGIPESFKVLLKELQSLGLDVEVLSED 1000
RNA_pol_Rpb2_6 pfam00562
RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of ...
690-1065 0e+00

RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain represents the hybrid binding domain and the wall domain. The hybrid binding domain binds the nascent RNA strand / template DNA strand in the Pol II transcription elongation complex. This domain contains the important structural motifs, switch 3 and the flap loop and binds an active site metal ion. This domain is also involved in binding to Rpb1 and Rpb3. Many of the bacterial members contain large insertions within this domain, as region known as dispensable region 2 (DRII).


Pssm-ID: 459854 [Multi-domain]  Cd Length: 371  Bit Score: 535.19  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    690 VAGLIPYPHHNQSPRNTYQCAMGKQAMGNIAYNQLNRMDTLLYLLVYPQRPLLTTRTIELVGYDKLGAGQNATVAVMSFS 769
Cdd:pfam00562    1 VASLIPFVDHNQSPRNTYQCAMGKQAMGIYTLNKFYRSDQNTYVLCYPQKPLVKTGAVEAGGFGELPLGQNAIVAVMSYT 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    770 GYDIEDAIVMNKSSLDRGFGRCIVMKKIVAmsQKYDNCTADRILIPQRTGPDaEKMQILDDDGLATPGEIIRPNDIYINK 849
Cdd:pfam00562   81 GYNQEDAIIINKSSVDRGFFTSIHIKEIEA--RKTKLGPIEEITRDIPNVSE-EALKKLDEDGIVRVGAEVKPGDILVGK 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    850 QVPVDTVTKFTSALSDSQYRPAREYFKGPEGETQVVDRVALCS-DKKGQLCIKYIIRHTRRPELGDKFSSRHGQKGVCGI 928
Cdd:pfam00562  158 VGPTELTKLLRAIFGEKARDVKDTSLKVPPGEEGVVDDVIVFElPPGGIKMVKVYIRQKRKPEVGDKFASRHGQKGVVSR 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    929 IIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRFHYGSAFGERSghaDKVETISATLVEKGFSYS 1008
Cdd:pfam00562  238 ILPQEDMPFTEDGIPPDIILNPHGVPSRMTIGQLLETHLGKAAALLGVFVDATPFDGAS---TEVEDIGELLEKAGYNYY 314
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 79529842   1009 GKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSK 1065
Cdd:pfam00562  315 GKEVLYDGRTGEPFEAPIFVGPIYYQKLKHMVDDKIHARSTGPYSLLTRQPLGGRAR 371
PRK09606 PRK09606
DNA-directed RNA polymerase subunit B''; Validated
28-531 5.23e-102

DNA-directed RNA polymerase subunit B''; Validated


Pssm-ID: 236587 [Multi-domain]  Cd Length: 494  Bit Score: 331.53  E-value: 5.23e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    28 STADKFQLVPEFLKVRGLVKQHLDSFNYFINVGIHKIVKANSRITSTVDPSIYLRFKKVRVGEPSIINVN-TVENINPHM 106
Cdd:PRK09606    1 MMEDRRVLSDAYFKEHRLVRHHIDSYNDFVDNGLQKIIDEQGPIETEIEDGVYVELGKIRVGKPVVKEADgSEREIYPME 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   107 CRLADMTYAAPIFVNIEYVHGSHGNKAksakDNVIIGRMPIMLRSCRCVLHGKDEEELARLGECPLDPGGYFIIKGTEKV 186
Cdd:PRK09606   81 ARLRNLTYSAPLYLEMSPVEGGEEEEP----EEVYIGELPVMVGSKICNLYGLSEEELIEVGEDPLDPGGYFIVNGSERV 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   187 LLIQEQLSKNRIIIDSDKKGNIN---ASVTSSTEMTKSKTVIQMEKEKI-YLFLHRFVKKIPIIIVLKAMGMESDQEIVQ 262
Cdd:PRK09606  157 LMTLEDLAPNKILVEKDERYGDRievAKVFSQRRGYRALVTVERNRDGLlEVSFPSVPGSIPFVILMRALGLETDEEIVE 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   263 MVGRDPRFSASLLPSIEEcvsEGVNTQKQALDYLEAKVKKisyGTPPE-KDGRALSILRDLFLAHVPVPDNNFRQKCFYV 341
Cdd:PRK09606  237 AVSDDPEIVKFMLENLEE---AEVDTQEEALEYIGKRVAP---GQTKEyRIKRAEYVIDRYLLPHLGVEPEVRRAKAHYL 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   342 GVMLRRMIEAMLNKDAMDDKDYVGNKRLELSGQlislLFEDLFKTMLSEAIKNVDHIL------NKPIRASRFDFSQCLN 415
Cdd:PRK09606  311 GRMAEACFELALGRREEDDKDHYANKRLKLAGD----LMEDLFRVAFNRLARDVKYQLeranmrNRELSIKTAVRSDVLT 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   416 KDsrysislgLERTLSTGNfdikrFRMHRKGMTQVLTRLSFIGSMGFITKI-------SPQFEKsrkvsgpRSLQPSQWG 488
Cdd:PRK09606  387 ER--------LEHAMATGN-----WVGGRTGVSQLLDRTDYMATLSHLRRVvsplsrsQPHFEA-------RDLHPTQWG 446
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 79529842   489 MLCPCDTPEGESCGLVKNLALMTHVTTDEEEGPLVAMCYKLGV 531
Cdd:PRK09606  447 RICPSETPEGPNCGLVKNFAQMVEISTGEDEEEVKEILKELGV 489
RNA_pol_Rpb2_1 pfam04563
RNA polymerase beta subunit; RNA polymerases catalyze the DNA dependent polymerization of RNA. ...
44-402 9.02e-96

RNA polymerase beta subunit; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain forms one of the two distinctive lobes of the Rpb2 structure. This domain is also known as the protrusion domain. The other lobe (pfam04561) is nested within this domain.


Pssm-ID: 367994 [Multi-domain]  Cd Length: 396  Bit Score: 311.24  E-value: 9.02e-96
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842     44 GLVKQHLDSFNYFINVGIHKIVKANSRITSTVDPS--------IYLRFKKVRVGEPSI-INVNTVENINPHMCRLADMTY 114
Cdd:pfam04563    1 GLVRQQLDSFNEFVDNDLQKIIDENALIESEFEIQhpgengdkLSLKFGQIRLGKPMFdETDGSTREIYPQECRLRNLTY 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    115 AAPIFVNIEYVHGshgNKAKSAKDNVIIGRMPIMLRSCRCVLHGKDEEELARLGECPLDPGGYFIIKGTEKVLLIQEQLS 194
Cdd:pfam04563   81 SAPLYVDLELSVY---NGEDIKPIEVFIGRLPIMLRSNACILSGATESELVKLGECPLDPGGYFIINGSEKVIVAQEHRS 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    195 KNRIIIDSD---KKGNINASVTSSTEMTKSKT---VIQMEKE----KIYLFLHRFVKKIPIIIVLKAMGMESDQEIVQMV 264
Cdd:pfam04563  158 RNHPIVFKKadpKKRGSVASVRSSAEISVRPDstsWVNVLEYlsngTIYFKFPYIKKEIPIVIILRALGFTSDREIFELI 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    265 ---GRDPRFSASLLPSIEECVSEGVNTQKQALDYLEAKVKKI-SYGTPPEKDGR-ALSILRDLFLAHVPVPDNNFRQKCF 339
Cdd:pfam04563  238 cydVNDQQLQEELLPSLEEGFKIRIQTQEQALDYIGGRGRAIfRMGRPREPRIKyAEEILQKEVLPHLGTYELDETKKAY 317
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 79529842    340 YVGVMLRRMIEAMLNKDAMDDKDYVGNKRLELSGQLISLLFEDLFKTMLSEAIKNVDHILNKP 402
Cdd:pfam04563  318 FIGYMIRRLLLLALGRREVDDRDHLGNKRLRLAGPLLASLFRVLFKKLVRDVRERLQKVLGSP 380
rpoB TIGR02013
DNA-directed RNA polymerase, beta subunit; This model describes orthologs of the beta subunit ...
33-1150 8.07e-67

DNA-directed RNA polymerase, beta subunit; This model describes orthologs of the beta subunit of Bacterial RNA polymerase. The core enzyme consists of two alpha chains, one beta chain, and one beta' subunit. [Transcription, DNA-dependent RNA polymerase]


Pssm-ID: 273928 [Multi-domain]  Cd Length: 1065  Bit Score: 245.73  E-value: 8.07e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842     33 FQLVPEFLKVRGLVKQHLDSFNYFI----------NVGIHKIVKANSRITSTVDpSIYLRFKKVRVGEPsiinVNTVENi 102
Cdd:TIGR02013    8 FGKIPEVLEVPNLLEIQLDSYDWFLqqdtppekrkEEGLEEVFKSIFPIEDYTG-NIELEYLSYRLGEP----KYSVEE- 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    103 nphmCRLADMTYAAPIFVNIEYVHGSHGNKAKSAKDNVIIGRMPIMLRScrcvlhgkdeeelarlgecpldpgGYFIIKG 182
Cdd:TIGR02013   82 ----CKERGLTYSAPLKVKLRLINKEEDGTKEIKEQDVYMGDIPLMTDR------------------------GTFIING 133
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    183 TEKVllIQEQLSKNRIIIDSDKKGNinasvTSSTEMTKSKTVI-------QME---KEKIYLFLHRfVKKIPIIIVLKAM 252
Cdd:TIGR02013  134 AERV--VVSQLHRSPGVFFSSEKDT-----TKSGKVLFSARIIpyrgswlEFEtdkKDVLYVRIDR-KRKLPATVLLRAL 205
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    253 GMESDQEIVQMVGRDPRFSASLLpsieecvSEGVNTQKQALDYLeakVKKISYGTPPEKDGrALSILRDLF-------LA 325
Cdd:TIGR02013  206 GYTIDTLILNRLGSGEYIRNTLR-------KDPTNSEEEALVEI---YRKLRPGEPPTVEA-ARSLLENLFfdpkrydLG 274
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    326 HV-----------PVPDnnfrqkcfYVGVM--------LRRMIEAMLNKDAMDDKDYVGNKRLELSGQLIsllfEDLFKT 386
Cdd:TIGR02013  275 RVgryklnkklglDVPE--------SIGVLtkediiatIKYLIKLRNGKGEIDDIDHLGNRRIRSVGELL----QNQFRV 342
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    387 MLSEAIKNVDHilnkpiRASRFDFsqclnkDSRYSISLGLERTLSTGnfdIKRFRMH---RKGMTQV-----LT---RLS 455
Cdd:TIGR02013  343 GLARMERIVRE------RMSTQDT------DTLTPQDLINAKPISAA---IKEFFGSsqlSQFMDQTnplaeLThkrRLS 407
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    456 FIGSMGfITKISPQFEKsrkvsgpRSLQPSQWGMLCPCDTPEGESCGLVKNLALMTHVTtdeeegplvamcyKLGVtdle 535
Cdd:TIGR02013  408 ALGPGG-LTRERAGFEV-------RDVHPTHYGRICPIETPEGPNIGLINSLSTYARVN-------------EYGF---- 462
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    536 vlsaeeLHTPdsflvilnglilgkhsrpqyfanslrrlrragkigefvsvftnekqhcvYVasdvgrvcrplviadkgis 615
Cdd:TIGR02013  463 ------IETP-------------------------------------------------YR------------------- 468
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    616 RVKqhhmkelqDGVRTFDDfirdgLIEYLDVNEENNALIAlyesDGTTELDEGA----------------EAAKADTTHI 679
Cdd:TIGR02013  469 KVK--------DGKVVVTD-----EIDYLTADEEDNYVIA----QANAPLDENGrfvedlvvaryrgeitLVSPDQVDYM 531
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    680 EIEPFTILGVVAGLIPYPHHNQSPRNTYQCAMGKQAM-------------------------------GNIAY------- 721
Cdd:TIGR02013  532 DVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVpllrseaplvgtgmeakvardsgavivakrgGVVEYvdakriv 611
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    722 --NQLNRMDTLLYLLVYP--------------QRPLLTtrtielVGyDKLGAGQ-----------------NATVAVMSF 768
Cdd:TIGR02013  612 irYDEDEEEPDGGIDIYRllkyqrsnqdtcinQRPIVS------VG-DRVEAGDvladgpstdlgelalgrNVLVAFMPW 684
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    769 SGYDIEDAIVMNKssldrgfgrCIVmKKIVAMS---QKYDNCTADRILIPQRTGPD-----AEKMQILDDDGLATPGEII 840
Cdd:TIGR02013  685 NGYNYEDAILISE---------RLV-KDDVFTSihiEEYEVEARDTKLGPEEITRDipnvsEEALRNLDENGIVRIGAEV 754
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    841 RPNDIYINKQVPvDTVTKFTS------ALSDSQYRPARE-YFKGPEGETQVVDRVALCSDKKG--------QLcIKYIIR 905
Cdd:TIGR02013  755 KAGDILVGKVTP-KGETELTPeekllrAIFGEKARDVRDtSLRVPPGVEGTVIDVKVFSREQGdelppgvnKL-VKVYIA 832
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    906 HTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIELLGSKAGVSCGRfhYGSAFGE 985
Cdd:TIGR02013  833 QKRKIQVGDKMAGRHGNKGVVSKILPIEDMPFLEDGTPVDIVLNPLGVPSRMNIGQILETHLGWAGKRLGR--KGVPIAT 910
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    986 RSGHADKVETISATLVEKGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSK 1065
Cdd:TIGR02013  911 PVFDGASEEEIKEYLEKAGLPRDGKVRLYDGRTGEQFDRPVTVGYMYMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQ 990
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   1066 NGGLRVGEMERDCLIAYGASMLIYERLMISSDpfEVQvcracGLLGYYNYKLKkavcttcknGDNIATMKLPYACKLLFQ 1145
Cdd:TIGR02013  991 FGGQRFGEMEVWALEAYGAAYTLQEMLTVKSD--DVV-----GRTKAYEAIVK---------GENVPEPGIPESFNVLIK 1054

                   ....*
gi 79529842   1146 ELQSM 1150
Cdd:TIGR02013 1055 ELQSL 1059
rpoB CHL00207
RNA polymerase beta subunit; Provisional
51-1152 3.86e-51

RNA polymerase beta subunit; Provisional


Pssm-ID: 214397 [Multi-domain]  Cd Length: 1077  Bit Score: 196.85  E-value: 3.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    51 DSFNYFINVGIHKIVKANSRItstVDPSIYLrfKKVRVGEPSIINVNtveNINPHMCRLADMTYAAPIFVNIEYVHGSHG 130
Cdd:CHL00207   16 TSFCWFLNEGLNEELNIFSKI---FDYTGNL--ELLLFGKNYKLKYP---KYNLLSAKSYDSNYSIQIYLPLKFINLKTN 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   131 nkaKSAKDNVIIGRMPIMLRScrcvlhgkdeeelarlgecpldpgGYFIIKGTEKVLLIQEQLSkNRIIIDSDKKgNINA 210
Cdd:CHL00207   88 ---KIKFINYLIGNLPKMTQR------------------------GTFIINGLERVIVSQIIRS-PGIYFKKEIK-KNSN 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   211 SVTSSTEMTKSKTVIQMEKEK---IYLFLHRfVKKIPIIIVLKAMGMeSDQEIVQMVgrdpRFSASLLPSIEECVSEGVN 287
Cdd:CHL00207  139 KIYSATLIPNRGSWIKFELDKnkeIWIRIDK-NRKKPLIIFLKALGL-TDQDIYSRL----TKSEFLKKLKPILLNSNSY 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   288 TQKQALDYLEAKVKKISYGTPPEKDGRALS------------ILRDLFLAHVPVPDNNFRQKCFYVGVM--LRRMIEAML 353
Cdd:CHL00207  213 TNEEILLEIYKNLSPIEPATVNDANQNLFSrffdpknydlgkVGRYKINNKLNLNIPERVRNLTYEDILsiIDKLINLKI 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   354 NKDAMDDKDYVGNKRLELSGQLISLLFEDLFKTmLSEAIKNvDHILnkpirasrFDFSQCLNKdsrysislglerTLSTG 433
Cdd:CHL00207  293 NKGNFDDIDHLKNRRVRSVGELLQNQFRIGLKR-LERILRN-RMTI--------CDIDSLSKF------------NLINP 350
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   434 NFDIKRFRMHRkGMTQVLTRLSFIGSMGFIT---KIS----PQFEKSRKVSGPRSLQPSQWGMLCPCDTPEGESCGLVKN 506
Cdd:CHL00207  351 KPLIALIREFF-GSSQLSQYMDQTNPLSELThkrRISilgpGGLDKDRISFAVRDIHPSHYGRICPIETPEGPNCGLIGS 429
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   507 LALMTHVttdeeegplvamcYKLGVtdlevlsaeeLHTPdsFLVILNGLIlgkhsrpQYFANSlrrlrragkigefvsvf 586
Cdd:CHL00207  430 LATNARI-------------NKFGF----------IETP--FYKVINGKV-------KKFGNP----------------- 460
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   587 tnekqhcVYVASDVGRVCRplvIADKGISRVKQHHMKELQDGVRTFDDFIrdglieylDVNEENNALIAlyesdgtteld 666
Cdd:CHL00207  461 -------IYLTADSEDLYR---IAPNDINLNKNNYFKKNIIPVRYKQEFK--------TVNPSKVDFIA----------- 511
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   667 egaeaakadtthieIEPFTILGVVAGLIPYPHHNQSPRNTYQCAMGKQAMGNI---------AYNQLNRMDTLL------ 731
Cdd:CHL00207  512 --------------ISPIQVFSIAESLIPFLEHNDANRALMGSNMQRQAVPLLypekpivgtGYEKQIALDSGMtiislt 577
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   732 ------------------------YLLVYP---------QRPL------LTTRTIELVGYD----KLGAGQNATVAVMSF 768
Cdd:CHL00207  578 egivvsvsaykiiiqddnnryihyYLQKYQrsnqntcinYRPIvwvgekINIGQILADGSDidnsELALGQNVLVAYMPW 657
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   769 SGYDIEDAIVMNKSSLDRGFGRCIVMKKI-VAMSQKYDNCTADRILIPQRTgpDAEKMQiLDDDGLATPGEIIRPNDIYI 847
Cdd:CHL00207  658 EGYNFEDAILINKRLVYEDLFTSIHIEKYeIELRQTKLGSEEITRNIPNVS--EYSLKN-LDENGIISIGSKVLAGDILV 734
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   848 NKQVPVDTVT-----KFTSALSDSQYRPAREY-FKGPEGET-QVVDRVALCSDKKGQL------CIKYIIRHTRRPELGD 914
Cdd:CHL00207  735 GKITPKGESDqlpegKLLRAIFGEKAKDVKDTsLRMPNGGYgRVIKVEIFSRSKGDELkfgyylKIRVFIAQIRKIQVGD 814
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   915 KFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIE-LLGSKAGVSCGRFHYGSaFGERSGH-ADK 992
Cdd:CHL00207  815 KLAGRHGNKGIISRILPRQDMPYLPDGTPPDIILNPLGVPSRMNVGQLFEcLLGLAGDNLNKRFKILP-FDEMYGSeYSR 893
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   993 V---ETISATLVEKGFSY------SGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGK 1063
Cdd:CHL00207  894 IlinNKLNQASIKNNEYWlfnsyhPGKMVLRDGRTGYKFKNPVTVGIAYMLKLIHLVDDKIHARTTGPYSLVTQQPLGGK 973
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  1064 SKNGGLRVGEMERDCLIAYGASMLIYERLMISSDPFEVqvcracgllgyynyklKKAVCTTCKNGDNIATMKLPYACKLL 1143
Cdd:CHL00207  974 AQHGGQRFGEMEVWALEAFGAAYTLKELLTIKSDDMQG----------------RNETLNAIVKGQPIPKPGTPESFKVL 1037

                  ....*....
gi 79529842  1144 FQELQSMNV 1152
Cdd:CHL00207 1038 MRELQSLGL 1046
rpoB PRK00405
DNA-directed RNA polymerase subunit beta; Reviewed
33-1097 4.86e-43

DNA-directed RNA polymerase subunit beta; Reviewed


Pssm-ID: 234749 [Multi-domain]  Cd Length: 1112  Bit Score: 171.05  E-value: 4.86e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    33 FQLVPEFLKVRGLVKQHLDSFNYFI-------NVGIHKIVKANSRITSTvDPSIYLRFKKVRVGEPsiinVNTVENinph 105
Cdd:PRK00405   15 FGKIKEVLELPNLLEIQLDSFDWFLqldvppeDEGLEEVFRSIFPIEDF-NGNLSLEFVSYELGEP----KYDVEE---- 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   106 mCRLADMTYAAPIFVNIEYVHGSHGNkAKSakDNVIIGRMPIMlrscrcvlhgkdeeelarlgecplDPGGYFIIKGTEK 185
Cdd:PRK00405   86 -CKERGLTYSAPLRVKLRLINKETGE-IKE--QEVYMGDIPLM------------------------TENGTFIINGTER 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   186 VllIQEQLskNR---IIIDSDKkgninaSVTSSTEMTKSKTVIQ-----ME-----KEKIYLFLHRfVKKIPIIIVLKAM 252
Cdd:PRK00405  138 V--IVSQL--HRspgVYFDHDK------DKTSSGKLLYSARIIPyrgswLEfefdpKDILYVRIDR-RRKLPVTVLLRAL 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   253 GMeSDQEIVQMVGRDPRFSASLLPSIEECVS--------------------------------------EGVNTQKQALD 294
Cdd:PRK00405  207 GY-SDEEILDLFYEKEEFGKEIEVPVEYLLGkvlaedivdeetgevlaeandeiteeldgpyirntlekDPTSSREEALV 285
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   295 YLeakVKKISYGTPPEKDGrALSILRDLF-------LAHV-----------PVPDNnfrqkcfyVGVM--------LRRM 348
Cdd:PRK00405  286 EI---YRRLRPGEPPTVEA-ARSLLENLFfdpkrydLSKVgryklnkklglDEDED--------VRVLtkediiatIKYL 353
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   349 IEAMLNKDAMDDKDYVGNKRLELSGQLIsllfEDLFKTMLS---------------EAIKNVDHILNKPIRASRFDF--- 410
Cdd:PRK00405  354 INLRNGKGEVDDIDHLGNRRVRSVGELL----QNQFRIGLSrmeravrermslqdlDTLTPQDLINAKPVVAAIKEFfgs 429
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   411 SQclnkdsrysislglertLStgnfdikRFrmhrkgMTQV-----LT---RLSFIGSMGfITKISPQFEksrkVsgpRSL 482
Cdd:PRK00405  430 SQ-----------------LS-------QF------MDQTnplseLThkrRLSALGPGG-LTRERAGFE----V---RDV 471
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   483 QPSQWGMLCPCDTPEGESCGLVKNLAlmTHVTTDEEeGPLVAMCYKL--G-VTDlEV--LSAEElhtPDSFLVILNGLIL 557
Cdd:PRK00405  472 HPTHYGRICPIETPEGPNIGLINSLA--TYARVNEY-GFIETPYRKVvdGkVTD-EIvyLTADE---EDNYVIAQANAPL 544
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   558 GKHSRpqyFANSLRRLRRAGkigEFVSVFTNE--------KQhCVYVAS---------DVGR-----------VcrPLVI 609
Cdd:PRK00405  545 DEDGR---FVDELVTARYKG---EFVLVPPEEvdymdvspKQ-VVSVAAslipflehdDANRalmgsnmqrqaV--PLLR 615
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   610 ADKGIsrvkqhhmkelqdgVRTfddfirdGlIEYLDVNEENNALIAlyESDGTTEldegaeaaKADTTHIEIEPFTILGV 689
Cdd:PRK00405  616 PEAPL--------------VGT-------G-MERRVARDSGAVVVA--KRDGVVE--------YVDASRIVVRVEELDPG 663
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   690 VAG-----LIPYPHHNQsprNTyqCamgkqamgniaYNQlnrmdtllyllvypqRPLLTtrtielVGyDKLGA------- 757
Cdd:PRK00405  664 EDGvdiynLIKFQRSNQ---NT--C-----------INQ---------------RPIVK------VG-DRVEKgdvladg 705
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   758 ----------GQNATVAVMSFSGYDIEDAIVMNK--------SSLDrgfgrcIVMKKIVAMSQK--YDNCTADrilIPQr 817
Cdd:PRK00405  706 pstdngelalGQNVLVAFMPWNGYNFEDAILISErlvkedvfTSIH------IEEYEIEARDTKlgPEEITRD---IPN- 775
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   818 TGPDAEKMqiLDDDGLATPGEIIRPNDIYINKqvpvdtVTkftsalsdsqyrpareyfkgPEGETQ-------------- 883
Cdd:PRK00405  776 VSEEALRN--LDESGIVRIGAEVKPGDILVGK------VT--------------------PKGETEltpeekllraifge 827
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   884 ----VVD---RValcsdKKGQ----LCIKYIIRHTRRPEL--------------------GDKFSSRHGQKGVCGIIIQQ 932
Cdd:PRK00405  828 kardVKDtslRV-----PHGEegtvIDVKVFTRIEQGDELppgvnklvkvyiaqkrkiqvGDKMAGRHGNKGVVSRILPV 902
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   933 EDFPFSELGICPDLIMNPHGFPSRMTVGKMIELlgskagvscgrfHYGSAfGERSGhaDKVET----------ISATLVE 1002
Cdd:PRK00405  903 EDMPYLEDGTPVDIVLNPLGVPSRMNIGQILET------------HLGWA-AKGLG--IKFATpvfdgakeeeIKELLEE 967
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  1003 KGFSYSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAY 1082
Cdd:PRK00405  968 AGLPEDGKTTLYDGRTGEPFDRPVTVGYMYMLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAY 1047
                        1290
                  ....*....|....*
gi 79529842  1083 GASMLIYERLMISSD 1097
Cdd:PRK00405 1048 GAAYTLQEMLTVKSD 1062
RNA_pol_Rpb2_7 pfam04560
RNA polymerase Rpb2, domain 7; RNA polymerases catalyze the DNA dependent polymerization of ...
1067-1158 1.74e-39

RNA polymerase Rpb2, domain 7; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Rpb2 is the second largest subunit of the RNA polymerase. This domain comprised of the structural domains anchor and clamp. The clamp region (C-terminal) contains a zinc-binding motif. The clamp region is named due to its interaction with the clamp domain found in Rpb1. The domain also contains a region termed "switch 4". The switches within the polymerase are thought to signal different stages of transcription.


Pssm-ID: 461355 [Multi-domain]  Cd Length: 87  Bit Score: 141.19  E-value: 1.74e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   1067 GGLRVGEMERDCLIAYGASMLIYERLMISSDPFEVQVCRACGLLGYYNYklkkavCTTCKNGDNIATMKLPYACKLLFQE 1146
Cdd:pfam04560    1 GGLRFGEMERWALIAYGAAHTLQERLTIKSDAYEVDVCGRCGLYAAYNK------CPICKGETDISPGYIPESFKLLFQE 74
                           90
                   ....*....|..
gi 79529842   1147 LQSMNVVPRLKL 1158
Cdd:pfam04560   75 LQSLGIDPRLLL 86
rpoB CHL00001
RNA polymerase beta subunit
37-1097 8.28e-39

RNA polymerase beta subunit


Pssm-ID: 214330 [Multi-domain]  Cd Length: 1070  Bit Score: 157.37  E-value: 8.28e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    37 PEFLKVRglvkqhLDSFNYFINVGIHKIVKANSRITSTvDPSIYLRF--KKVRVGEPSIinvntveniNPHMCRLADMTY 114
Cdd:CHL00001   13 PGFNQIQ------FEGFCRFIDQGLTEELSKFPKIEDT-DQEIEFQLfvETYQLVEPLI---------KERDAVYESLTY 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   115 AAPIFVNieyVHGSHGNKAKSAKDNVIIGRMPIMlrscrcvlhgkdeeelarlgecplDPGGYFIIKGTEKVLLIQeqls 194
Cdd:CHL00001   77 SSELYVP---AGLIWKKSRDMQEQTVFIGNIPLM------------------------NSLGTFIINGIYRVVINQ---- 125
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   195 knriIIDS---------DKKGNinaSVTSSTEMTKSKTVIQME---KEKIYLFLHRfVKKIPIIIVLKAMGMESDqEIVQ 262
Cdd:CHL00001  126 ----ILRSpgiyyrselDHNGI---SVYTGTIISDWGGRLELEidrKARIWARVSR-KQKISILVLLSAMGLNLR-EILD 196
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   263 MVgRDPRFsasLLPSIEECVSEGVNTQKQALdyLEAKVKKISYGTPPEKDGRALSILRDLFlahvpvpdnnFRQKCfYVG 342
Cdd:CHL00001  197 NV-CYPEI---FLSFLNDKEKKKIGSKENAI--LEFYQQFACVGGDPVFSESLCKELQKKF----------FQQRC-ELG 259
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   343 VMLRRMIeamlnkdamddkdyvgNKRLEL--SGQLISLLFEDLfktmLSEA---IK---------NVDHILNKPIRaSRF 408
Cdd:CHL00001  260 RIGRRNM----------------NRKLNLdiPENNTFLLPQDV----LAAAdylIGmkfgmgtldDIDHLKNKRIR-SVA 318
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   409 DFSQ-----CLNKdsrysislgLERTLSTgnfDIKRFRMHRKGMT-------QVLTRL--SFIGS---MGFITKISP--Q 469
Cdd:CHL00001  319 DLLQdqfglALNR---------LENAVRG---TICGAIRRKLIPTpqnlvtsTPLTTTyeSFFGShplSQFLDQTNPltE 386
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   470 FEKSRKVS--GP------------RSLQPSQWGMLCPCDTPEGESCGLVKNLAlmTHVTTDEE---EGPLVAMCYKLGVT 532
Cdd:CHL00001  387 IVHGRKLSslGPggltgrtasfrvRDIHPSHYGRICPIDTSEGINAGLIGSLA--IHARIGHWgslESPFYEISERSKEE 464
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   533 DLEVLSAEElhtpDSFLVILNGLILGKHSRPQYFANSLRRLRRagkigEFVSVftnekqhcvyvasdvgrvcrplviadk 612
Cdd:CHL00001  465 RMVYLSPSE----DEYYMIAAGNSLALNQGIQEEQVVPARYRQ-----EFLTI--------------------------- 508
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   613 gisRVKQHHMKelqdGVRTFDDF-IRDGLIEYLDVNEENNAL---------IALYESD----GT-----TELDEGAEA-A 672
Cdd:CHL00001  509 ---AWEQIHLR----SIFPFQYFsIGASLIPFLEHNDANRALmgsnmqrqaVPLSRSEkcivGTglerqVALDSGVVAiA 581
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   673 KADTTHIEIEPFTILGVVAGlipypHHNQSPRNTYQCAmgkqamgniayNQlnrmDTLLYllvypQRPllttrTIELVGY 752
Cdd:CHL00001  582 EHEGKIIYTDTDKIILSGNG-----DTLSIPLVMYQRS-----------NK----NTCMH-----QKP-----QVRRGKC 631
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   753 DK---------------LGAGQNATVAVMSFSGYDIEDAIVMNKssldrgfgrCIVMKKIVAmS---QKYD------NCT 808
Cdd:CHL00001  632 VKkgqiladgaatvggeLALGKNVLVAYMPWEGYNFEDAVLISE---------RLVYEDIYT-SfhiRKYEiqthvtSQG 701
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   809 ADRIL--IPQRtgpDAEKMQILDDDGLATPGEIIRPNDIYINKQVPVDTVT-------KFTSALSDSQYRPAREY-FKGP 878
Cdd:CHL00001  702 PERITkeIPHL---EAHLLRNLDKNGIVMLGSWVETGDILVGKLTPQEAEEssyapegRLLRAIFGIQVSTSKETcLKLP 778
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   879 EG-ETQVVDrVALCSDKKGQLCIKYIIR----HTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGF 953
Cdd:CHL00001  779 IGgRGRVID-VRWIQKKGGSSYNPETIHvyilQKREIQVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVLNPLGV 857
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   954 PSRMTVGKMIE-LLGSkAGVSCGRfHYGSA-FGERSGhadkvETISATLVekgFS------------------YSGKDLL 1013
Cdd:CHL00001  858 PSRMNVGQIFEcLLGL-AGDLLNR-HYRIApFDERYE-----QEASRKLV---FSelyeaskqtanpwvfepeYPGKSRL 927
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  1014 YSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLM 1093
Cdd:CHL00001  928 FDGRTGDPFEQPVTIGKAYILKLIHQVDDKIHARSSGPYALVTQQPLRGRSKQGGQRVGEMEVWALEGFGVAYILQEMLT 1007

                  ....
gi 79529842  1094 ISSD 1097
Cdd:CHL00001 1008 YKSD 1011
PRK09603 PRK09603
DNA-directed RNA polymerase subunit beta/beta';
900-1150 2.36e-26

DNA-directed RNA polymerase subunit beta/beta';


Pssm-ID: 181983 [Multi-domain]  Cd Length: 2890  Bit Score: 117.72  E-value: 2.36e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   900 IKYIIRHTRRPELGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIE----LLGSKAGVSCG 975
Cdd:PRK09603 1078 VKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQILEmhlgLVGKEFGKQIA 1157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   976 RF------------------------HYGSAFGERSGHADKVETIS-----------ATLVEKGFS-------------- 1006
Cdd:PRK09603 1158 SMledktkdfakelrakmleianainEKDPLTIHALENCSDEELLEyakdwskgvkmAIPVFEGISqekfyklfelakia 1237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842  1007 YSGKDLLYSGISGEPVEAYIFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASM 1086
Cdd:PRK09603 1238 MDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAH 1317
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79529842  1087 LIYERLMISSDPFEvqvcracGLLGYYnyklkKAVcttcKNGDNIATMKLPYACKLLFQELQSM 1150
Cdd:PRK09603 1318 TLKEMLTIKSDDIR-------GRENAY-----RAI----AKGEQVGESEIPETFYVLTKELQSL 1365
RNA_pol_Rpb2_4 pfam04566
RNA polymerase Rpb2, domain 4; RNA polymerases catalyze the DNA dependent polymerization of ...
550-611 5.92e-25

RNA polymerase Rpb2, domain 4; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 4, is also known as the external 2 domain.


Pssm-ID: 428012 [Multi-domain]  Cd Length: 62  Bit Score: 98.59  E-value: 5.92e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 79529842    550 VILNGLILGKHSRPQYFANSLRRLRRAGKIGEFVSVFTNEKQHCVYVASDVGRVCRPLVIAD 611
Cdd:pfam04566    1 VFLNGNLIGVHRDPEELVETLRKLRRSGKISEEVSIVRDIREKEVRINTDGGRVCRPLIIVE 62
RNA_pol_Rpb2_2 pfam04561
RNA polymerase Rpb2, domain 2; RNA polymerases catalyze the DNA dependent polymerization of ...
194-370 8.30e-25

RNA polymerase Rpb2, domain 2; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Rpb2 is the second largest subunit of the RNA polymerase. This domain forms one of the two distinctive lobes of the Rpb2 structure. This domain is also known as the lobe domain. DNA has been demonstrated to bind to the concave surface of the lobe domain, and plays a role in maintaining the transcription bubble. Many of the bacterial members contain large insertions within this domain, as region known as dispensable region 1 (DRI).


Pssm-ID: 398318 [Multi-domain]  Cd Length: 185  Bit Score: 102.81  E-value: 8.30e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    194 SKNRIIIDSDK-KGNINASVTSSTEMTKSKTVIQMEKEKIYLFLHRFVK-KIPIIIVLKAMGMESDQEIVQMV---GRDP 268
Cdd:pfam04561    1 RSNGIYVEKELdKNGIIATYTSSLISNRGSWLKLEIDGKTLIWSRPSKKrKIPIVIFLKALGLVSDREILDRLcydFNDP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842    269 RFSASLLPSIEECvsEGVNTQKQALDYLEAKVKKIS---YGTPPEKDGRALSILRDLFLAHVPV--PDNNFRQKCFYVGV 343
Cdd:pfam04561   81 QMLELLKPELEEA--ENIYTQEEALDYIGKGFALRRgeePRLQRAREILYSRDPKYNLNKHLGLnePFENERLKAQDILY 158
                          170       180
                   ....*....|....*....|....*..
gi 79529842    344 MLRRMIEAMLNKDAMDDKDYVGNKRLE 370
Cdd:pfam04561  159 MIDRLLNLKLGRRKPDDIDHLGNKRVR 185
PRK14844 PRK14844
DNA-directed RNA polymerase subunit beta/beta';
904-1097 3.68e-21

DNA-directed RNA polymerase subunit beta/beta';


Pssm-ID: 173305 [Multi-domain]  Cd Length: 2836  Bit Score: 100.85  E-value: 3.68e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   904 IRHTRRPelGDKFSSRHGQKGVCGIIIQQEDFPFSELGICPDLIMNPHGFPSRMTVGKMIEL--------LGSKAGV--- 972
Cdd:PRK14844 1077 VKHSLQP--GDKMAGRHGNKGVISRVVPVEDMPYLEDGTPVDIILNPLGVPSRMNVGQILEThvgwackkLGEKVGNild 1154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   973 --------------------------------------------------------------------SCGRFH------ 978
Cdd:PRK14844 1155 einkiksafckgirslnddnftkfaaayldnkkienidddeitasvlntpnknalndelnelvenylnSCKSAYsnlrnf 1234
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79529842   979 ------YGS-------------------AFGERSG--------HADKVETISATLVEKGFSYSGKDLLYSGISGEPVEAY 1025
Cdd:PRK14844 1235 lievysCGSnvsicnnirdisdnnliefARKLRDGipvaapvfEGPKDEQIAKLFELAGLDNSGQAVLYDGCSGEKFDRK 1314
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 79529842  1026 IFMGPIYYQKLKHMVLDKMHARGSGPRVMMTRQPTEGKSKNGGLRVGEMERDCLIAYGASMLIYERLMISSD 1097
Cdd:PRK14844 1315 VTVGYMYMLKLHHLVDGKIHARSVGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSD 1386
RNA_pol_Rpb2_3 pfam04565
RNA polymerase Rpb2, domain 3; RNA polymerases catalyze the DNA dependent polymerization of ...
449-512 7.67e-19

RNA polymerase Rpb2, domain 3; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 3, s also known as the fork domain and is proximal to catalytic site.


Pssm-ID: 428011 [Multi-domain]  Cd Length: 67  Bit Score: 81.42  E-value: 7.67e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 79529842    449 QVLTRLSFIGSMGFITKISP---QFEKSRKVSGPRSLQPSQWGMLCPCDTPEGESCGLVKNLALMTH 512
Cdd:pfam04565    1 QVLDRTNYLSTLSHLRRVNSprgGLFREMKTTEVRDLHPSHWGRICPVETPEGPNCGLVKHLALYAR 67
RNA_pol_Rpb2_5 pfam04567
RNA polymerase Rpb2, domain 5; RNA polymerases catalyze the DNA dependent polymerization of ...
632-683 1.12e-13

RNA polymerase Rpb2, domain 5; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 5, is also known as the external 2 domain.


Pssm-ID: 428013 [Multi-domain]  Cd Length: 53  Bit Score: 66.41  E-value: 1.12e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 79529842    632 FDDFIRDGLIEYLDVNEENNALIALYESDGTTELDEGAEAAKADT-THIEIEP 683
Cdd:pfam04567    1 WSDLLREGVIEYLDAEEEETSMIAMTPEDLEESSREEREGPYAHTyTHCEIHP 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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