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    scyl3 SCY1-like, kinase-like 3 [ Danio rerio (zebrafish) ]

    Gene ID: 323839, updated on 9-Dec-2024

    Summary

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    Official Symbol
    scyl3provided by ZNC
    Official Full Name
    SCY1-like, kinase-like 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2559
    See related
    Ensembl:ENSDARG00000027046 AllianceGenome:ZFIN:ZDB-GENE-030131-2559
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55575; wu:fc11d06; wu:faa95c04
    Summary
    Predicted to enable ATP binding activity and protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Orthologous to human SCYL3 (SCY1 like pseudokinase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See scyl3 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (34012950..34028969, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (34110071..34126090, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene zona pellucida glycoprotein 3a, tandem duplicate 1 Neighboring gene fignl1 interacting regulator of recombination and mitosis Neighboring gene proteoglycan 4b Neighboring gene translocated promoter region b, nuclear basket protein Neighboring gene phosducin b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. Liu Z, et al. J Biol Chem, 2011 Aug 12. PMID 21669877, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein-associating with the carboxyl-terminal domain of ezrin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199657.1 → NP_955951.1  protein-associating with the carboxyl-terminal domain of ezrin

      See identical proteins and their annotated locations for NP_955951.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044195
      UniProtKB/TrEMBL
      Q803U0
      Related
      ENSDARP00000033868.5, ENSDART00000033817.7
      Conserved Domains (2) summary
      sd00044
      Location:339 → 367
      HEAT; HEAT repeat [structural motif]
      cl21453
      Location:32 → 247
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      34012950..34028969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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