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    camta1a calmodulin binding transcription activator 1a [ Danio rerio (zebrafish) ]

    Gene ID: 797322, updated on 9-Dec-2024

    Summary

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    Official Symbol
    camta1aprovided by ZNC
    Official Full Name
    calmodulin binding transcription activator 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090312-183
    See related
    Ensembl:ENSDARG00000077428 AllianceGenome:ZFIN:ZDB-GENE-090312-183
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-223i19.5
    Summary
    Predicted to enable double-stranded DNA binding activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in nonprogressive cerebellar ataxia with mental retardation. Orthologous to human CAMTA1 (calmodulin binding transcription activator 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See camta1a in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (30061366..30698695, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (30134851..30772265, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103909694 Neighboring gene uncharacterized LOC137489186 Neighboring gene urotensin 2, alpha Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 11a Neighboring gene THAP domain containing, apoptosis associated protein 3 Neighboring gene ASXL transcriptional regulator 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress. Ebrahimie E, et al. J Alzheimers Dis, 2016 Mar 31. PMID 27031468
    2. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calmodulin-binding transcription activator 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      30061366..30698695 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470004.2 → XP_021325679.1  calmodulin-binding transcription activator 1 isoform X6

      UniProtKB/TrEMBL
      A0A8M9PL98
      Related
      ENSDARP00000126402.1, ENSDART00000146633.4
      Conserved Domains (4) summary
      smart01076
      Location:32 → 148
      CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
      cd00204
      Location:1157 → 1254
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:1156 → 1199
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:966 → 1045
      TIG; IPT/TIG domain

    2. XM_021470005.2 → XP_021325680.1  calmodulin-binding transcription activator 1 isoform X7

      UniProtKB/TrEMBL
      A0A8M9PWY3
      Conserved Domains (4) summary
      smart01076
      Location:66 → 182
      CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
      cd00204
      Location:1144 → 1241
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:1143 → 1186
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:953 → 1032
      TIG; IPT/TIG domain

    3. XM_021470006.2 → XP_021325681.1  calmodulin-binding transcription activator 1 isoform X8

      UniProtKB/TrEMBL
      A0A8M9PTM2
      Conserved Domains (4) summary
      smart01076
      Location:66 → 182
      CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
      cd00204
      Location:1191 → 1288
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:1190 → 1233
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:1000 → 1079
      TIG; IPT/TIG domain

    4. XM_009296996.4 → XP_009295271.1  calmodulin-binding transcription activator 1 isoform X5

      UniProtKB/TrEMBL
      A0A8M3ANU5
      Conserved Domains (5) summary
      smart01076
      Location:66 → 182
      CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
      cd00204
      Location:1191 → 1288
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam01833
      Location:1000 → 1079
      TIG; IPT/TIG domain
      pfam12796
      Location:1195 → 1287
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:1190 → 1233
      ANK; ANK repeat [structural motif]

    5. XM_021470003.2 → XP_021325678.1  calmodulin-binding transcription activator 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PFK5
      Conserved Domains (4) summary
      smart01076
      Location:66 → 182
      CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
      cd00204
      Location:1191 → 1288
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:1190 → 1233
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:1000 → 1079
      TIG; IPT/TIG domain

    6. XM_017353704.3 → XP_017209193.1  calmodulin-binding transcription activator 1 isoform X4

      UniProtKB/TrEMBL
      A0A8M6Z3X4

    7. XM_005162333.5 → XP_005162390.1  calmodulin-binding transcription activator 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M2B977
      Conserved Domains (5) summary
      smart01076
      Location:66 → 182
      CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
      cd00204
      Location:1191 → 1288
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam01833
      Location:1000 → 1079
      TIG; IPT/TIG domain
      pfam12796
      Location:1195 → 1287
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:1190 → 1233
      ANK; ANK repeat [structural motif]

    8. XM_021470002.2 → XP_021325677.1  calmodulin-binding transcription activator 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9P5K3
      Conserved Domains (4) summary
      smart01076
      Location:66 → 182
      CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
      cd00204
      Location:1191 → 1288
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:1190 → 1233
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:1000 → 1079
      TIG; IPT/TIG domain

    9. XM_021470007.2 → XP_021325682.1  calmodulin-binding transcription activator 1 isoform X9

      UniProtKB/TrEMBL
      A0A8M9P5K7
      Conserved Domains (2) summary
      cd00204
      Location:99 → 196
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:98 → 141
      ANK; ANK repeat [structural motif]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395157.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      88874..176510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473717.2 → XP_021329392.1  calmodulin-binding transcription activator 1 isoform X16

      UniProtKB/TrEMBL
      A0A8M9PE49
      Conserved Domains (3) summary
      cd00204
      Location:970 → 1067
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:969 → 1012
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:779 → 858
      TIG; IPT/TIG domain

    2. XM_021473715.2 → XP_021329390.1  calmodulin-binding transcription activator 1 isoform X14

      UniProtKB/TrEMBL
      A0A8M9Q822
      Conserved Domains (3) summary
      cd00204
      Location:970 → 1067
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:969 → 1012
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:779 → 858
      TIG; IPT/TIG domain

    3. XM_021473714.2 → XP_021329389.1  calmodulin-binding transcription activator 1 isoform X11

      UniProtKB/TrEMBL
      A0A8M9PX14
      Conserved Domains (3) summary
      cd00204
      Location:970 → 1067
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:969 → 1012
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:779 → 858
      TIG; IPT/TIG domain

    4. XM_068219065.1 → XP_068075166.1  calmodulin-binding transcription activator 1 isoform X13

    5. XM_068219064.1 → XP_068075165.1  calmodulin-binding transcription activator 1 isoform X12

    6. XM_068219063.1 → XP_068075164.1  calmodulin-binding transcription activator 1 isoform X10

    7. XM_021473716.2 → XP_021329391.1  calmodulin-binding transcription activator 1 isoform X15

      UniProtKB/TrEMBL
      A0A8M9Q3X1
      Conserved Domains (3) summary
      cd00204
      Location:923 → 1020
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:922 → 965
      ANK; ANK repeat [structural motif]
      pfam01833
      Location:732 → 811
      TIG; IPT/TIG domain

    8. XM_021473718.2 → XP_021329393.1  calmodulin-binding transcription activator 1 isoform X9

      UniProtKB/TrEMBL
      A0A8M9PQV2
      Conserved Domains (2) summary
      cd00204
      Location:99 → 196
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:98 → 141
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
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