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    MCM3 minichromosome maintenance complex component 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 281302, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MCM3provided by VGNC
    Official Full Name
    minichromosome maintenance complex component 3provided by VGNC
    Primary source
    VGNC:VGNC:31309
    See related
    BGD:BT18197; Ensembl:ENSBTAG00000010721
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MCM3 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (24694546..24711930, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene interleukin 17A Neighboring gene interleukin 17F Neighboring gene uncharacterized LOC132343630 Neighboring gene uncharacterized LOC112443867 Neighboring gene translation machinery-associated protein 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA strand elongation involved in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair via break-induced replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MCM complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA replication licensing factor MCM3
    Names
    MCM3 minichromosome maintenance deficient 3
    NP_001013604.2
    XP_059736188.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013586.2 → NP_001013604.2  DNA replication licensing factor MCM3

      See identical proteins and their annotated locations for NP_001013604.2

      Status: PROVISIONAL

      Source sequence(s)
      BC114737
      UniProtKB/Swiss-Prot
      A4FUD9
      UniProtKB/TrEMBL
      A0AAF6YVB0
      Related
      ENSBTAP00000014194.7, ENSBTAT00000014194.7
      Conserved Domains (3) summary
      smart00350
      Location:109 → 654
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:17 → 129
      MCM_N; MCM N-terminal domain
      cl21455
      Location:340 → 479
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      24694546..24711930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059880205.1 → XP_059736188.1  DNA replication licensing factor MCM3 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A4FUD9.1 GenPept UniProtKB/Swiss-Prot:A4FUD9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.