|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
109-654 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 734.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 109 KHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRS---VHYCPATKKTIERRYSDLTSLVAFPSSSVYPTkdeennPLE 185
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPT------PFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 186 TEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLP-GKKGGYTSGT--FRTVLIA 262
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 263 CNVK----QMSKDVQP----SFSAEDIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH 334
Cdd:smart00350 155 NHVRkldyKRSFEDSSfsvqSLSDEEEEEIRKLSK--DPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 335 IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKM 414
Cdd:smart00350 233 IRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKM 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 415 SDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQD 494
Cdd:smart00350 313 DDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERD 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 495 REISDHVLRMHRYRAPGEQDGDamplgsavdilatddpnfspddqqdtqiyekhdnllhgikkkkEKMVSAAFMRKYIHV 574
Cdd:smart00350 393 RELAKHVVDLHRYSHPEEDEAF-------------------------------------------EPPLSQEKLRKYIAY 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 575 AK-IIKPVLTQESAAYIAEEYSRLRSQDSmSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAY 653
Cdd:smart00350 430 AReKIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
.
gi 164448574 654 F 654
Cdd:smart00350 509 I 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
298-652 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 592.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 298 QLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 377
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 378 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 457
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 458 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYrapgeqdgdamplgsavdilatddpnfspd 537
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 538 dqqdtqiyekhdnllhgikkkkekmvsAAFMRKYIHVAK-IIKPVLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTAR 616
Cdd:cd17754 211 ---------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITAR 263
|
330 340 350
....*....|....*....|....*....|....*.
gi 164448574 617 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17754 264 TLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
19-651 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 535.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 19 YLDFLDDEEdqgiYQSKVRELISDNQYR--LIVNVNDLRRKNEKRANRLLSNAFEELVAFQRALKDFVASIdatYAKQYE 96
Cdd:COG1241 9 FEEFLRRYK----YRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP---YDVSLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 97 EFYIGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA--TKKTIERRYSDLTslvafpsssvY 174
Cdd:COG1241 82 DAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ----------E 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 175 PTKDEE---NNPLETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLPGKKGGY 251
Cdd:COG1241 150 PHECPGcgrQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 252 TSGTFRTVLIACNVKQMSKDVQP-SFSAEDIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLE 330
Cdd:COG1241 230 KSTIFDLYLEANSIEVEEKEFEEiEITEEDEEKIKELSK--DPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 331 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRGVVCID 409
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 410 EFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQM 489
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 490 DPEQDREISDHVLRMHRYRAPGEQDGDAMplgsavdiLATDDPNFSPDdqqdtqiyekhdnllhgikkkkekmvsaaFMR 569
Cdd:COG1241 468 DEERDRELARHILKVHRAGELLEQEIEEE--------TEEVKPEIDPD-----------------------------LLR 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 570 KYIHVAK-IIKPVLTQESAAYIAEEYSRLRSQDSMSSDTArtsPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVEL 648
Cdd:COG1241 511 KYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV---PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRL 587
|
...
gi 164448574 649 VQY 651
Cdd:COG1241 588 VDS 590
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
12-651 |
2.13e-168 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 502.53 E-value: 2.13e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 12 LREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLSNAFEELVAFQRALKDFVASIDATY 91
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 92 AKQYEEFYIGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTSLVAFPSS 171
Cdd:NF040949 81 AEEVAKFHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 172 SVYPtKDEENNPLETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLPG---KK 248
Cdd:NF040949 159 TVCP-VCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 249 GgyTSGTFRTVLIACNVKQMSKDVQP-SFSAEDIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVER 327
Cdd:NF040949 238 G--SRPIFKNYIEANHIEVSQKELEEvEITEEDEEKILELAK--DPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 328 DLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVC 407
Cdd:NF040949 314 VLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLD 487
Cdd:NF040949 394 IDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 488 QMDPEQDREISDHVLRMHryrapgeQDGDAMPlgsavdilatddPNFSPDdqqdtqiyekhdnLLhgikkkkekmvsaaf 567
Cdd:NF040949 474 KPNEERDRRLARHILDVH-------SGKEKVK------------PEIDPD-------------LL--------------- 506
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 568 mRKYIHVA-KIIKPVLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAV 646
Cdd:NF040949 507 -KKYIAYArKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAI 585
|
....*
gi 164448574 647 ELVQY 651
Cdd:NF040949 586 RLMLA 590
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
280-505 |
4.85e-129 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 384.19 E-value: 4.85e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 280 DIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVL 359
Cdd:pfam00493 1 DEEEIKELAK--RPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 360 CTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH 439
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 164448574 440 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMH 505
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
113-654 |
3.00e-82 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 282.27 E-value: 3.00e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 113 PRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTSLVafpssSVYPTKDEENNPL-------- 184
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEH-----YEYVIQGEVNEPLlcnecnsk 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 185 ---ETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDR--------------------VKPGDRVQVVG-- 239
Cdd:PTZ00111 293 ytfELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEiymkdnevinlnlyddlidsVKTGDRVTVVGil 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 240 ---------TYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDV-----QPSFSAEDIAKIKKFSktRSKDIFDQLARSLAP 305
Cdd:PTZ00111 373 kvtpirtstTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLkylgnENDFSDLQVYKILELS--RNPMIYRILLDSFAP 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 306 SIHGHDYVKKAILCLLLGGVERDLENGSHI---------RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376
Cdd:PTZ00111 451 SIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSV 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 377 GLTAAVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPV 455
Cdd:PTZ00111 531 GLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPI 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 456 YGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRmhRYRAPGEQDgdamplgsavdilATDDpnFS 535
Cdd:PTZ00111 611 NSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK--DFLLPHMTG-------------SGND--ED 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 536 PDDQQDTQIYEkhDNLLHgiKKKKEKMVSAAFMRKYIHVAKI-IKPVLTQESAAYIAEEYSRLRSQDSMSSDT------- 607
Cdd:PTZ00111 674 TYDRSNTMHVE--DESLR--SEKDYNKNDLDMLRMYIKFSKLhCFPKLSDEAKKVITREYVKMRQGNFQTSNLdelehaq 749
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 608 -------------ARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYF 654
Cdd:PTZ00111 750 edddddlyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTF 809
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
16-104 |
6.72e-16 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 73.48 E-value: 6.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 16 QRDYLDFLD----DEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLSNAFEELVAFQRALKDFVASI--DA 89
Cdd:pfam14551 1 KRKFKDFLEefreDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 164448574 90 TYAKQYEEFYIGLEG 104
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
109-654 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 734.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 109 KHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRS---VHYCPATKKTIERRYSDLTSLVAFPSSSVYPTkdeennPLE 185
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPT------PFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 186 TEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLP-GKKGGYTSGT--FRTVLIA 262
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 263 CNVK----QMSKDVQP----SFSAEDIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH 334
Cdd:smart00350 155 NHVRkldyKRSFEDSSfsvqSLSDEEEEEIRKLSK--DPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 335 IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKM 414
Cdd:smart00350 233 IRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKM 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 415 SDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQD 494
Cdd:smart00350 313 DDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERD 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 495 REISDHVLRMHRYRAPGEQDGDamplgsavdilatddpnfspddqqdtqiyekhdnllhgikkkkEKMVSAAFMRKYIHV 574
Cdd:smart00350 393 RELAKHVVDLHRYSHPEEDEAF-------------------------------------------EPPLSQEKLRKYIAY 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 575 AK-IIKPVLTQESAAYIAEEYSRLRSQDSmSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAY 653
Cdd:smart00350 430 AReKIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
.
gi 164448574 654 F 654
Cdd:smart00350 509 I 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
298-652 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 592.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 298 QLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 377
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 378 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 457
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 458 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYrapgeqdgdamplgsavdilatddpnfspd 537
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 538 dqqdtqiyekhdnllhgikkkkekmvsAAFMRKYIHVAK-IIKPVLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTAR 616
Cdd:cd17754 211 ---------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITAR 263
|
330 340 350
....*....|....*....|....*....|....*.
gi 164448574 617 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17754 264 TLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
19-651 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 535.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 19 YLDFLDDEEdqgiYQSKVRELISDNQYR--LIVNVNDLRRKNEKRANRLLSNAFEELVAFQRALKDFVASIdatYAKQYE 96
Cdd:COG1241 9 FEEFLRRYK----YRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP---YDVSLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 97 EFYIGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA--TKKTIERRYSDLTslvafpsssvY 174
Cdd:COG1241 82 DAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ----------E 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 175 PTKDEE---NNPLETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLPGKKGGY 251
Cdd:COG1241 150 PHECPGcgrQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 252 TSGTFRTVLIACNVKQMSKDVQP-SFSAEDIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLE 330
Cdd:COG1241 230 KSTIFDLYLEANSIEVEEKEFEEiEITEEDEEKIKELSK--DPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 331 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRGVVCID 409
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 410 EFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQM 489
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 490 DPEQDREISDHVLRMHRYRAPGEQDGDAMplgsavdiLATDDPNFSPDdqqdtqiyekhdnllhgikkkkekmvsaaFMR 569
Cdd:COG1241 468 DEERDRELARHILKVHRAGELLEQEIEEE--------TEEVKPEIDPD-----------------------------LLR 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 570 KYIHVAK-IIKPVLTQESAAYIAEEYSRLRSQDSMSSDTArtsPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVEL 648
Cdd:COG1241 511 KYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV---PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRL 587
|
...
gi 164448574 649 VQY 651
Cdd:COG1241 588 VDS 590
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
12-651 |
2.13e-168 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 502.53 E-value: 2.13e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 12 LREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLSNAFEELVAFQRALKDFVASIDATY 91
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 92 AKQYEEFYIGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTSLVAFPSS 171
Cdd:NF040949 81 AEEVAKFHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 172 SVYPtKDEENNPLETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLPG---KK 248
Cdd:NF040949 159 TVCP-VCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 249 GgyTSGTFRTVLIACNVKQMSKDVQP-SFSAEDIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVER 327
Cdd:NF040949 238 G--SRPIFKNYIEANHIEVSQKELEEvEITEEDEEKILELAK--DPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 328 DLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVC 407
Cdd:NF040949 314 VLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLD 487
Cdd:NF040949 394 IDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 488 QMDPEQDREISDHVLRMHryrapgeQDGDAMPlgsavdilatddPNFSPDdqqdtqiyekhdnLLhgikkkkekmvsaaf 567
Cdd:NF040949 474 KPNEERDRRLARHILDVH-------SGKEKVK------------PEIDPD-------------LL--------------- 506
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 568 mRKYIHVA-KIIKPVLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAV 646
Cdd:NF040949 507 -KKYIAYArKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAI 585
|
....*
gi 164448574 647 ELVQY 651
Cdd:NF040949 586 RLMLA 590
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
299-650 |
1.37e-141 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 419.83 E-value: 1.37e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 299 LARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17706 2 LADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17706 82 TAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDamplgsavdilatddpnfspdd 538
Cdd:cd17706 162 YNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQVKP---------------------- 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 539 qqdtqiyekhdnllhgikKKKEKMVSAAFMRKYIHVAKIIKPVLTQESAAYIAEEYSRLRSQdsmsSDTARTSPVTARTL 618
Cdd:cd17706 220 ------------------EEDGIPIDIELLRKYILYARQIHPKISEEAREKLVRWYVELRKE----SERRSTIPITARQL 277
|
330 340 350
....*....|....*....|....*....|..
gi 164448574 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
Cdd:cd17706 278 ESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVR 309
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
280-505 |
4.85e-129 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 384.19 E-value: 4.85e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 280 DIAKIKKFSKtrSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVL 359
Cdd:pfam00493 1 DEEEIKELAK--RPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 360 CTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH 439
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 164448574 440 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMH 505
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
299-652 |
1.97e-124 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 375.59 E-value: 1.97e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 299 LARSLAPSIHGHDYVKKAILCLLLGGVERDlENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHryrapgeQDGDAMPlgSAVDILatdDPNfspdd 538
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVH-------QHNKQPD--SDFEPL---DPK----- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 539 qqdtqiyekhdnllhgikkkkekmvsaaFMRKYIHVAKIIKPVLTQESAAYIAEEYSRLRSQDSMSSDTARTSPvtaRTL 618
Cdd:cd17758 224 ----------------------------LLRAYIALAKRKRPTVPPALADYIVQAYVEMRQEAKRSKDFTFTTP---RTL 272
|
330 340 350
....*....|....*....|....*....|....
gi 164448574 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17758 273 LAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
299-650 |
2.33e-117 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 357.85 E-value: 2.33e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 299 LARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17756 2 ISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17756 82 TASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAmplgsavdilatddpnfspdd 538
Cdd:cd17756 162 YDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQEN--------------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 539 qqdtqiyekhdnllhgikkkkEKMVSAAFMRKYIHVAKI-IKPVLTQESAAYIAEEYSRLRS---QDSMSSDTARTSPVT 614
Cdd:cd17756 221 ---------------------EGEIPISKLKRYIAYCRAkCAPRLSEEAAEKLSNHYVTIRKdvrQNELESDNRSSIPIT 279
|
330 340 350
....*....|....*....|....*....|....*.
gi 164448574 615 ARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
Cdd:cd17756 280 VRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQ 315
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
299-649 |
2.72e-116 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 354.37 E-value: 2.72e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 299 LARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRApgeqdgDAMplgsavdilatdDPNFSPDD 538
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKRE------EAI------------EPPFTAEQ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 539 qqdtqiyekhdnllhgikkkkekmvsaafMRKYIHVAKIIKPVLTQESAAYIAEEYSRLRsQDSMSSDTARTSPVTARTL 618
Cdd:cd17757 224 -----------------------------LKRYIAYARTFKPKLTKEAKDELVEQYKELR-QDDASGSTRSSYRITVRQL 273
|
330 340 350
....*....|....*....|....*....|.
gi 164448574 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELV 649
Cdd:cd17757 274 ESLIRLSEAIARLHCSDEVTPEHVEEAARLL 304
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
297-650 |
1.44e-113 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 347.52 E-value: 1.44e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 297 DQLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVY 456
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 457 GRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQdgdamplgsavdilatdDPNFSP 536
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREI-----------------KPEIDP 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 537 DdqqdtqiyekhdnllhgikkkkekmvsaaFMRKYIHVA-KIIKPVLTQESAAYIAEEYSRLRSQdsmSSDTARTSPVTA 615
Cdd:cd17761 224 D-----------------------------LLRKYIAYArKNVRPVLTEEAKQLIKDFYVEMRKS---GQETPSPVPITA 271
|
330 340 350
....*....|....*....|....*....|....*
gi 164448574 616 RTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
Cdd:cd17761 272 RQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
299-652 |
1.12e-109 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 337.49 E-value: 1.12e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 299 LARSLAPSIHGHDYVKKAILCLLLGGVERDLEN-GSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 377
Cdd:cd17755 2 LARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 378 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 457
Cdd:cd17755 82 LTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIGS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 458 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHryrapgeqdgdamplgsavdilatddpnfspd 537
Cdd:cd17755 162 RYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLY-------------------------------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 538 dQQDTQIYEKHDnllhgikkkkekMVSAAFMRKYIHVAKI-IKPVLTQESAAYIAEEYSRLRsqdSMSSDTARTSPVTAR 616
Cdd:cd17755 210 -LEDTPEHIQDE------------VLDVEVLTDYISYAREhIHPKLSEEAAQELVQAYVDMR---KMGSDARKRITATPR 273
|
330 340 350
....*....|....*....|....*....|....*.
gi 164448574 617 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17755 274 QLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
302-649 |
1.66e-106 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 329.79 E-value: 1.66e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 302 SLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAA 381
Cdd:cd17753 5 SIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 382 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQ 461
Cdd:cd17753 85 VRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYNP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 462 YKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRyrapgeqdgdamplgsavdilaTDDPNFSPDDQQD 541
Cdd:cd17753 165 TLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHV----------------------RSHPENDEDREGE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 542 tqiyeKHDNLLHGIKKKKEKMVSAAFMRKYIHVAKI-IKPVLTQESAAYIAEEYSRLRsQDSMSSDTArtsPVTARTLET 620
Cdd:cd17753 223 -----EEKNQRQRPKETKVEPIPQELLRKYIHYAREkVRPKLNQMDMDKVSRVYADLR-KESMATGSL---PITVRHLES 293
|
330 340
....*....|....*....|....*....
gi 164448574 621 LIRLATAHAKARMSKTVDLQDAEEAVELV 649
Cdd:cd17753 294 IIRISEAHAKMHLREYVSEEDVDMAIRVM 322
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
113-654 |
3.00e-82 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 282.27 E-value: 3.00e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 113 PRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTSLVafpssSVYPTKDEENNPL-------- 184
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEH-----YEYVIQGEVNEPLlcnecnsk 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 185 ---ETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDR--------------------VKPGDRVQVVG-- 239
Cdd:PTZ00111 293 ytfELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEiymkdnevinlnlyddlidsVKTGDRVTVVGil 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 240 ---------TYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDV-----QPSFSAEDIAKIKKFSktRSKDIFDQLARSLAP 305
Cdd:PTZ00111 373 kvtpirtstTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLkylgnENDFSDLQVYKILELS--RNPMIYRILLDSFAP 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 306 SIHGHDYVKKAILCLLLGGVERDLENGSHI---------RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376
Cdd:PTZ00111 451 SIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSV 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 377 GLTAAVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPV 455
Cdd:PTZ00111 531 GLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPI 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 456 YGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRmhRYRAPGEQDgdamplgsavdilATDDpnFS 535
Cdd:PTZ00111 611 NSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK--DFLLPHMTG-------------SGND--ED 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 536 PDDQQDTQIYEkhDNLLHgiKKKKEKMVSAAFMRKYIHVAKI-IKPVLTQESAAYIAEEYSRLRSQDSMSSDT------- 607
Cdd:PTZ00111 674 TYDRSNTMHVE--DESLR--SEKDYNKNDLDMLRMYIKFSKLhCFPKLSDEAKKVITREYVKMRQGNFQTSNLdelehaq 749
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 608 -------------ARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYF 654
Cdd:PTZ00111 750 edddddlyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTF 809
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
299-652 |
3.17e-73 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 241.30 E-value: 3.17e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 299 LARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 379 TaaVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPvYGR 458
Cdd:cd17760 82 T--VTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLrmhryrapgEQDGDAmplgsavdilatddpnfspdd 538
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL---------ENKGEP--------------------- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 539 qqdtqiyekhdnllhgikKKKEKMVSAAFMRKYIHVAKIIKPVLTQESAAyIAEEYSRLRSQdsmsSDTARTSPVTARTL 618
Cdd:cd17760 209 ------------------SKSSKLWSMEKMRTYFCLIKNLRPVLSDEANA-ILLRYYQLQRQ----SDCRNAARTTIRML 265
|
330 340 350
....*....|....*....|....*....|....
gi 164448574 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17760 266 ESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
299-652 |
4.09e-69 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 229.73 E-value: 4.09e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 299 LARSLAPSIHGHDYVKKAILCLLLGGVER--DLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKyaDDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDmDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVY 456
Cdd:cd17759 82 GLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 457 GRYDQYKTPMENIGLQDSLLSRFDLLFIMLDqmDPEQDReisDHVLRMHryrapgeqdgdamplgsavdilatddpnfsp 536
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLD--TPSEEH---DHLLSEH------------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 537 ddqqdtqiyekHDNLlhgikkkkEKMVSAAfmRKYIHvakiikPVLTQESAAYIAEEYSRLRSQdsmsSDTARTSPVTAR 616
Cdd:cd17759 205 -----------HQLL--------RKYISYA--RQYVN------PVLSKDASEALQEFYLELRKQ----NQLADSSPITTR 253
|
330 340 350
....*....|....*....|....*....|....*.
gi 164448574 617 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17759 254 QLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
114-245 |
1.93e-36 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 133.38 E-value: 1.93e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 114 RTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTSLVAFPSSSVYPtkdeenNPLETEygLSVY 193
Cdd:pfam17207 3 RDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITEPTKCPNPECGNKDP------FKLVHE--KSKF 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 164448574 194 KDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLP 245
Cdd:pfam17207 75 VDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
567-650 |
7.67e-23 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 92.99 E-value: 7.67e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 567 FMRKYIHVAKI-IKPVLTQESAAYIAEEYSRLRSqdsMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEA 645
Cdd:pfam17855 2 LLRKYIAYAREkIKPKLSEEAREKLVDAYVELRK---ESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEA 78
|
....*
gi 164448574 646 VELVQ 650
Cdd:pfam17855 79 IRLLK 83
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
16-104 |
6.72e-16 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 73.48 E-value: 6.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 16 QRDYLDFLD----DEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLSNAFEELVAFQRALKDFVASI--DA 89
Cdd:pfam14551 1 KRKFKDFLEefreDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 164448574 90 TYAKQYEEFYIGLEG 104
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
297-512 |
6.21e-07 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 52.09 E-value: 6.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 297 DQLARSLAPSIHGHDYVKKAIL-CLLLGGverdlengshirgdiNILLIGDPSVAKSQLLR---YVLCTAPRAIPTTgrg 372
Cdd:COG0714 4 ARLRAEIGKVYVGQEELIELVLiALLAGG---------------HLLLEGVPGVGKTTLAKalaRALGLPFIRIQFT--- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 373 ssgVGLTAA-VT----TDQETGERRLEAGAmVLAdrGVVCIDEFDKMSDmdRT--AIHEVMEQGRVTIakAGIHARLNAR 445
Cdd:COG0714 66 ---PDLLPSdILgtyiYDQQTGEFEFRPGP-LFA--NVLLADEINRAPP--KTqsALLEAMEERQVTI--PGGTYKLPEP 135
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 446 CSVLAAANPVygrydqyktpmENIG---LQDSLLSRFdLLFIMLDQMDPEQDREIsdhvLRMHRYRAPGE 512
Cdd:COG0714 136 FLVIATQNPI-----------EQEGtypLPEAQLDRF-LLKLYIGYPDAEEEREI----LRRHTGRHLAE 189
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
340-479 |
6.12e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 43.44 E-value: 6.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 340 NILLIGDPSVAKSQLLRYV---LCTAPRAIpttgrgssgVGLTAAVTTDQETGERRLEAGAMVLADR---------GVVC 407
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLaaaLSNRPVFY---------VQLTRDTTEEDLFGRRNIDPGGASWVDGplvraaregEIAV 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164448574 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAG--IHARLNARcSVLAAANPVYGRydqyktPMEnigLQDSLLSRF 479
Cdd:pfam07728 72 LDEINRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPLDRG------LNE---LSPALRSRF 135
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
396-454 |
1.21e-04 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 44.06 E-value: 1.21e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 164448574 396 GAMVLADRGVVCIDEfdkMSDMDRTAI---HEVMEQGRVTIAKAGIHARLNARCSVLAAANP 454
Cdd:pfam01078 100 GEISLAHNGVLFLDE---LPEFKRRVLeslRQPLEDGEITISRARAKVTFPARFQLVAAMNP 158
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
340-485 |
5.93e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 40.98 E-value: 5.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164448574 340 NILLIGDPSVAKSQLLRYVLCTAPRaipttgRGSSGVGLTAAVTT-------DQETGERRLEAGAMVLADRGVVCIDEFD 412
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFR------PGAPFLYLNASDLLeglvvaeLFGHFLVRLLFELAEKAKPGVLFIDEID 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 164448574 413 KMSDMDRTAIHEVMEQGRVTIAKagiharlNARCSVLAAANpvygrydqyktPMENIGLQDSLLSRFDLLFIM 485
Cdd:cd00009 95 SLSRGAQNALLRVLETLNDLRID-------RENVRVIGATN-----------RPLLGDLDRALYDRLDIRIVI 149
|
|
| YifB |
COG0606 |
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ... |
396-454 |
1.71e-03 |
|
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440371 [Multi-domain] Cd Length: 502 Bit Score: 41.56 E-value: 1.71e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 164448574 396 GAMVLADRGVVCIDEfdkMSDMDRTAIhEV----MEQGRVTIAKAGIHARLNARCSVLAAANP 454
Cdd:COG0606 290 GEISLAHNGVLFLDE---LPEFSRRVL-EAlrqpLEDGEVTISRANGSVTYPARFQLVAAMNP 348
|
|
| |
