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    CG7084 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42606, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7084provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038938
    Locus tag
    Dmel_CG7084
    See related
    AllianceGenome:FB:FBgn0038938
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7084
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in acute kidney failure. Orthologous to human SLC22A1 (solute carrier family 22 member 1); SLC22A2 (solute carrier family 22 member 2); and SLC22A3 (solute carrier family 22 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7084 in Genome Data Viewer
    Location:
    94A4-94A4; 3-74 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22298805..22304420)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18124527..18130142)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46261 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional profiles of plasticity for desiccation stress in Drosophila. Clemson AS, et al. Comp Biochem Physiol B Biochem Mol Biol, 2018 Feb. PMID 29128643
    2. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Engelhart DC, et al. Int J Mol Sci, 2020 Mar 15. PMID 32183456, Free PMC Article
    3. The Drosophila blood-brain barrier: development and function of a glial endothelium. Limmer S, et al. Front Neurosci, 2014. PMID 25452710, Free PMC Article
    4. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
    5. Function-informed transcriptome analysis of Drosophila renal tubule. Wang J, et al. Genome Biol, 2004. PMID 15345053, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7084-PB
    CG7084-PC
    CG7084-PE
    CG7084-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      22298805..22304420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300531.1 → NP_001287460.1  uncharacterized protein Dmel_CG7084, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287460.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VD40
      Conserved Domains (2) summary
      cd06174
      Location:184 → 542
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:64 → 552
      2A0119; cation transport protein

    2. NM_169999.3 → NP_732707.1  uncharacterized protein Dmel_CG7084, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732707.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VD40
      Related
      FBpp0083599
      Conserved Domains (2) summary
      cd06174
      Location:184 → 542
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:64 → 552
      2A0119; cation transport protein

    3. NM_001260306.2 → NP_001247235.2  uncharacterized protein Dmel_CG7084, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247235.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VD40
      Conserved Domains (2) summary
      cd06174
      Location:184 → 542
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:64 → 552
      2A0119; cation transport protein

    4. NM_142759.3 → NP_651016.1  uncharacterized protein Dmel_CG7084, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651016.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VD40
      Related
      FBpp0290408
      Conserved Domains (2) summary
      cd06174
      Location:184 → 542
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:64 → 552
      2A0119; cation transport protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IH51 Q8IH51
    Q9VD40 Q9VD40

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