C36A4.4 putative UDP-N-acetylglucosamine pyrophosphorylase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C36A4.4
Official Full Name: putative UDP-N-acetylglucosamine pyrophosphorylase
Primary source: WormBase:WBGene00007965
Locus tag: CELE_C36A4.4
See related: AllianceGenome:WB:WBGene00007965
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable uridylyltransferase activity. Predicted to be located in cytoplasm. Orthologous to human UAP1 (UDP-N-acetylglucosamine pyrophosphorylase 1) and UAP1L1 (UDP-N-acetylglucosamine pyrophosphorylase 1 like 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C36A4.4 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 5

Sequence:: Chromosome: III; NC_003281.10 (3841265..3843614, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

K06B9.2 (e-PCR)
- UniSTS:311435

C36A4.4 (e-PCR)
- UniSTS:313817

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
NOT enables UDP-N-acetylglucosamine diphosphorylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables uridylyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
NOT involved_in UDP-N-acetylglucosamine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative UDP-N-acetylglucosamine pyrophosphorylase

NP_497777.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

3841265..3843614 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_065376.6 → NP_497777.1 putative UDP-N-acetylglucosamine pyrophosphorylase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497777.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q18493

Conserved Domains (1) summary

cd04193
Location:89 → 409

UDPGlcNAc_PPase; UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc