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    ABI2 abl interactor 2 [ Homo sapiens (human) ]

    Gene ID: 10152, updated on 10-Dec-2024

    Summary

    Official Symbol
    ABI2provided by HGNC
    Official Full Name
    abl interactor 2provided by HGNC
    Primary source
    HGNC:HGNC:24011
    See related
    Ensembl:ENSG00000138443 MIM:606442; AllianceGenome:HGNC:24011
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AIP1; ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB
    Summary
    Enables several functions, including SH3 domain binding activity; proline-rich region binding activity; and ubiquitin protein ligase binding activity. Contributes to small GTPase binding activity. Involved in several processes, including Rac protein signal transduction; positive regulation of cellular component organization; and zonula adherens assembly. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in several cellular components, including actin filament; filopodium tip; and lamellipodium. Part of SCAR complex. Is active in adherens junction. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in brain (RPKM 35.9), thyroid (RPKM 13.9) and 21 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ABI2 in Genome Data Viewer
    Location:
    2q33.2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (203328394..203432169)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (203810332..203914077)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (204193117..204296892)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 20 subfamily A member 1 Neighboring gene RNA, 7SL, cytoplasmic 670, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:204192004-204192974 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12255 Neighboring gene mitochondrial ribosomal protein L50 pseudogene 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:204209822-204210322 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17011 Neighboring gene MPRA-validated peak4020 silencer Neighboring gene tRNA-Glu (anticodon TTC) 9-1 Neighboring gene Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12256 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12257 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12258 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr2:204464991-204465874 Neighboring gene zinc finger protein 207 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    BioGRID CRISPR Screen Phenotypes (13 hits/1268 screens)

    EBI GWAS Catalog

    Description
    Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.
    EBI GWAS Catalog
    GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables SH3 domain binding PubMed 
    enables SH3 domain binding PubMed 
    enables cytoskeletal anchor activity PubMed 
    enables identical protein binding PubMed 
    enables kinase binding PubMed 
    enables proline-rich region binding PubMed 
    enables protein binding PubMed 
    enables signaling adaptor activity  
    enables signaling adaptor activity PubMed 
    contributes_to small GTPase binding PubMed 
    enables ubiquitin protein ligase binding PubMed 
    Component Evidence Code Pubs
    part_of SCAR complex  
    part_of SCAR complex PubMed 
    colocalizes_with actin filament PubMed 
    is_active_in actin-based cell projection  
    is_active_in adherens junction PubMed 
    located_in adherens junction  
    located_in cytoplasm PubMed 
    located_in cytoskeleton  
    located_in cytosol PubMed 
    is_active_in dendritic spine  
    located_in filopodium tip PubMed 
    is_active_in lamellipodium  
    located_in lamellipodium PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    abl interactor 2
    Names
    abelson interactor 2
    abl binding protein 3
    abl-interacting protein 1 (SH3-containing protein)
    abl-interactor protein 2b
    arg protein tyrosine kinase-binding protein
    arg-binding protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282925.3 → NP_001269854.1  abl interactor 2 isoform a

      See identical proteins and their annotated locations for NP_001269854.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform a.
      Source sequence(s)
      AC018891, AC080075
      Consensus CDS
      CCDS63093.1
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      UniProtKB/TrEMBL
      A0A7D9NKC8
      Related
      ENSP00000295851.4, ENST00000295851.10
      Conserved Domains (3) summary
      cd11972
      Location:452 → 512
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:270 → 397
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    2. NM_001282926.3 → NP_001269855.1  abl interactor 2 isoform b

      See identical proteins and their annotated locations for NP_001269855.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
      Source sequence(s)
      AC018891, AC080075
      Consensus CDS
      CCDS63094.1
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      UniProtKB/TrEMBL
      A0A0C4DG21
      Related
      ENSP00000391433.1, ENST00000424558.5
      Conserved Domains (3) summary
      cd11972
      Location:446 → 506
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:264 → 391
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    3. NM_001282927.2 → NP_001269856.1  abl interactor 2 isoform d

      See identical proteins and their annotated locations for NP_001269856.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in its 5' UTR, differs in the presence and absence of exons in the 5' coding region, initiates translation at an alternate start codon, and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (d) has a distinct N-terminus and is shorter than isoform a. Variants 4 and 6 both encode the same isoform (d).
      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      Q9NYB9
      Conserved Domains (2) summary
      cd11972
      Location:340 → 400
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:48 → 118
      Abi_HHR; Abl-interactor HHR
    4. NM_001282932.2 → NP_001269861.1  abl interactor 2 isoform e

      See identical proteins and their annotated locations for NP_001269861.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in its 5' UTR, differs in the presence and absence of exons in the 5' coding region, initiates translation at an alternate start codon, and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (e) has a distinct N-terminus and is shorter than isoform a.
      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      B7Z836, E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:329 → 389
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:37 → 107
      Abi_HHR; Abl-interactor HHR
    5. NM_001375662.1 → NP_001362591.1  abl interactor 2 isoform f

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variant 8, encodes isoform f.
      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      B7Z612
      Conserved Domains (3) summary
      cd11972
      Location:407 → 467
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:196 → 332
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    6. NM_001375663.1 → NP_001362592.1  abl interactor 2 isoform f

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variant 7, encodes isoform f.
      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      B7Z612
      Conserved Domains (3) summary
      cd11972
      Location:407 → 467
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:196 → 332
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    7. NM_001375664.1 → NP_001362593.1  abl interactor 2 isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9), as well as variant 10, encodes isoform g.
      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:329 → 389
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:147 → 274
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    8. NM_001375665.1 → NP_001362594.1  abl interactor 2 isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10), as well as variant 9, encodes isoform g.
      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:329 → 389
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:147 → 274
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    9. NM_001375666.1 → NP_001362595.1  abl interactor 2 isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11), as well as variant 12, encodes isoform h.
      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:311 → 371
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    10. NM_001375667.1 → NP_001362596.1  abl interactor 2 isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12), as well as variant 11, encodes isoform h.
      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:311 → 371
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    11. NM_001375668.1 → NP_001362597.1  abl interactor 2 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13), as well as variant 14, encodes isoform i.
      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:291 → 351
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    12. NM_001375669.1 → NP_001362598.1  abl interactor 2 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14), as well as variant 13, encodes isoform i.
      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:291 → 351
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    13. NM_001375670.1 → NP_001362599.1  abl interactor 2 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15) encodes the longest isoform (j).
      Source sequence(s)
      AC018891, AC080075
      Consensus CDS
      CCDS92932.1
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      UniProtKB/TrEMBL
      F8WAL6, J3KNB2
      Related
      ENSP00000261018.9, ENST00000261018.12
      Conserved Domains (3) summary
      cd11972
      Location:481 → 541
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:270 → 406
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    14. NM_001375671.1 → NP_001362600.1  abl interactor 2 isoform k

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:480 → 540
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:269 → 405
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    15. NM_001375672.1 → NP_001362601.1  abl interactor 2 isoform l

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EP65
      Conserved Domains (3) summary
      PHA03247
      Location:270 → 406
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:481 → 515
      SH3; Src Homology 3 domain superfamily
    16. NM_001375673.1 → NP_001362602.1  abl interactor 2 isoform m

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:479 → 539
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:270 → 406
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    17. NM_001375674.1 → NP_001362603.1  abl interactor 2 isoform n

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EP65
      Conserved Domains (3) summary
      PHA03247
      Location:269 → 405
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:480 → 514
      SH3; Src Homology 3 domain superfamily
    18. NM_001375675.1 → NP_001362604.1  abl interactor 2 isoform o

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:475 → 535
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:264 → 400
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    19. NM_001375676.1 → NP_001362605.1  abl interactor 2 isoform p

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      PHA03247
      Location:270 → 399
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 169
      Abi_HHR; Abl-interactor HHR
    20. NM_001375677.1 → NP_001362606.1  abl interactor 2 isoform q

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:451 → 511
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:269 → 396
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    21. NM_001375678.1 → NP_001362607.1  abl interactor 2 isoform r

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:447 → 507
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:221 → 351
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 169
      Abi_HHR; Abl-interactor HHR
    22. NM_001375679.1 → NP_001362608.1  abl interactor 2 isoform s

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:436 → 496
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:225 → 361
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:48 → 124
      Abi_HHR; Abl-interactor HHR
    23. NM_001375680.1 → NP_001362609.1  abl interactor 2 isoform t

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:432 → 492
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:221 → 357
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    24. NM_001375681.1 → NP_001362610.1  abl interactor 2 isoform u

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:431 → 491
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:220 → 356
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    25. NM_001375682.1 → NP_001362611.1  abl interactor 2 isoform v

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:430 → 490
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:221 → 357
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    26. NM_001375683.1 → NP_001362612.1  abl interactor 2 isoform w

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:426 → 486
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:215 → 351
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    27. NM_001375684.1 → NP_001362613.1  abl interactor 2 isoform x

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:425 → 485
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:214 → 350
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    28. NM_001375685.1 → NP_001362614.1  abl interactor 2 isoform y

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:418 → 478
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:221 → 351
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    29. NM_001375686.1 → NP_001362615.1  abl interactor 2 isoform z

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:414 → 448
      SH3; Src Homology 3 domain superfamily
    30. NM_001375687.1 → NP_001362616.1  abl interactor 2 isoform aa

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:413 → 473
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    31. NM_001375688.1 → NP_001362617.1  abl interactor 2 isoform bb

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:412 → 472
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    32. NM_001375689.1 → NP_001362618.1  abl interactor 2 isoform cc

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:413 → 447
      SH3; Src Homology 3 domain superfamily
    33. NM_001375690.1 → NP_001362619.1  abl interactor 2 isoform dd

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:411 → 471
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    34. NM_001375691.1 → NP_001362620.1  abl interactor 2 isoform ee

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:407 → 467
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:225 → 352
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:48 → 124
      Abi_HHR; Abl-interactor HHR
    35. NM_001375692.1 → NP_001362621.1  abl interactor 2 isoform ff

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:403 → 463
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:221 → 348
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    36. NM_001375693.1 → NP_001362622.1  abl interactor 2 isoform gg

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:402 → 462
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:220 → 347
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    37. NM_001375695.1 → NP_001362624.1  abl interactor 2 isoform hh

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      B7Z612
      Conserved Domains (3) summary
      cd11972
      Location:401 → 461
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:190 → 326
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    38. NM_001375696.1 → NP_001362625.1  abl interactor 2 isoform ii

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:400 → 460
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 163
      Abi_HHR; Abl-interactor HHR
    39. NM_001375698.1 → NP_001362627.1  abl interactor 2 isoform jj

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Consensus CDS
      CCDS92933.1
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      UniProtKB/TrEMBL
      E9PEZ7
      Related
      ENSP00000408898.1, ENST00000430418.5
      Conserved Domains (3) summary
      cd11972
      Location:397 → 457
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:215 → 342
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    40. NM_001375699.1 → NP_001362628.1  abl interactor 2 isoform kk

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:396 → 456
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:214 → 341
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    41. NM_001375702.1 → NP_001362631.1  abl interactor 2 isoform ll

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:396 → 456
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:214 → 341
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    42. NM_001375704.1 → NP_001362633.1  abl interactor 2 isoform mm

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      pfam07815
      Location:93 → 163
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:414 → 449
      SH3; Src Homology 3 domain superfamily
    43. NM_001375706.1 → NP_001362635.1  abl interactor 2 isoform nn

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:385 → 445
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    44. NM_001375707.1 → NP_001362636.1  abl interactor 2 isoform oo

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:384 → 444
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    45. NM_001375708.1 → NP_001362637.1  abl interactor 2 isoform pp

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:385 → 419
      SH3; Src Homology 3 domain superfamily
    46. NM_001375709.1 → NP_001362638.1  abl interactor 2 isoform qq

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:384 → 418
      SH3; Src Homology 3 domain superfamily
    47. NM_001375710.1 → NP_001362639.1  abl interactor 2 isoform rr

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:383 → 443
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 163
      Abi_HHR; Abl-interactor HHR
    48. NM_001375711.1 → NP_001362640.1  abl interactor 2 isoform ss

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:378 → 438
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:196 → 323
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    49. NM_001375712.1 → NP_001362641.1  abl interactor 2 isoform tt

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EP65
      Conserved Domains (3) summary
      PHA03247
      Location:221 → 348
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:403 → 438
      SH3; Src Homology 3 domain superfamily
    50. NM_001375714.1 → NP_001362643.1  abl interactor 2 isoform uu

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:376 → 436
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:165 → 301
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    51. NM_001375717.1 → NP_001362646.1  abl interactor 2 isoform vv

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:374 → 434
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:48 → 124
      Abi_HHR; Abl-interactor HHR
    52. NM_001375719.1 → NP_001362648.1  abl interactor 2 isoform ww

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
      Conserved Domains (3) summary
      cd11972
      Location:373 → 433
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:191 → 318
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:63 → 139
      Abi_HHR; Abl-interactor HHR
    53. NM_001375721.1 → NP_001362650.1  abl interactor 2 isoform xx

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:369 → 429
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:48 → 118
      Abi_HHR; Abl-interactor HHR
    54. NM_001375722.1 → NP_001362651.1  abl interactor 2 isoform yy

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:368 → 428
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:48 → 118
      Abi_HHR; Abl-interactor HHR
    55. NM_001375723.1 → NP_001362652.1  abl interactor 2 isoform zz

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:365 → 425
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    56. NM_001375724.1 → NP_001362653.1  abl interactor 2 isoform aaa

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:364 → 424
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    57. NM_001375725.1 → NP_001362654.1  abl interactor 2 isoform bbb

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:363 → 423
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    58. NM_001375726.1 → NP_001362655.1  abl interactor 2 isoform ccc

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:362 → 422
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    59. NM_001375727.1 → NP_001362656.1  abl interactor 2 isoform ddd

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:358 → 418
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:147 → 283
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 95
      Abi_HHR; Abl-interactor HHR
    60. NM_001375728.1 → NP_001362657.1  abl interactor 2 isoform eee

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:358 → 418
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    61. NM_001375729.1 → NP_001362658.1  abl interactor 2 isoform fff

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:357 → 417
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:146 → 282
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 95
      Abi_HHR; Abl-interactor HHR
    62. NM_001375730.1 → NP_001362659.1  abl interactor 2 isoform ggg

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:357 → 417
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    63. NM_001375731.1 → NP_001362660.1  abl interactor 2 isoform hhh

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:356 → 416
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    64. NM_001375732.1 → NP_001362661.1  abl interactor 2 isoform iii

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:347 → 407
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:165 → 292
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    65. NM_001375733.1 → NP_001362662.1  abl interactor 2 isoform jjj

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:341 → 401
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:159 → 286
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    66. NM_001375734.1 → NP_001362663.1  abl interactor 2 isoform kkk

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      Q53SH3
      Conserved Domains (2) summary
      cd11972
      Location:340 → 400
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    67. NM_001375735.1 → NP_001362664.1  abl interactor 2 isoform lll

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:338 → 398
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 89
      Abi_HHR; Abl-interactor HHR
    68. NM_001375736.1 → NP_001362665.1  abl interactor 2 isoform mmm

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:338 → 398
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:156 → 283
      PHA03247; large tegument protein UL36; Provisional
    69. NM_001375737.1 → NP_001362666.1  abl interactor 2 isoform nnn

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      pfam07815
      Location:93 → 163
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:364 → 399
      SH3; Src Homology 3 domain superfamily
    70. NM_001375738.1 → NP_001362667.1  abl interactor 2 isoform ooo

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:336 → 396
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    71. NM_001375739.1 → NP_001362668.1  abl interactor 2 isoform ppp

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:335 → 395
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    72. NM_001375740.1 → NP_001362669.1  abl interactor 2 isoform rrr

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:334 → 394
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 163
      Abi_HHR; Abl-interactor HHR
    73. NM_001375741.1 → NP_001362670.1  abl interactor 2 isoform sss

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:329 → 389
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    74. NM_001375742.1 → NP_001362671.1  abl interactor 2 isoform ttt

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:328 → 388
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:146 → 273
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    75. NM_001375743.1 → NP_001362672.1  abl interactor 2 isoform uuu

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:329 → 363
      SH3; Src Homology 3 domain superfamily
    76. NM_001375744.1 → NP_001362673.1  abl interactor 2 isoform vvv

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (1) summary
      cd11972
      Location:326 → 386
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    77. NM_001375745.1 → NP_001362674.1  abl interactor 2 isoform www

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:326 → 386
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:146 → 273
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 95
      Abi_HHR; Abl-interactor HHR
    78. NM_001375746.1 → NP_001362675.1  abl interactor 2 isoform xxx

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (1) summary
      cd11972
      Location:325 → 385
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    79. NM_001375747.1 → NP_001362676.1  abl interactor 2 isoform yyy

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:319 → 379
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:168 → 253
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:48 → 118
      Abi_HHR; Abl-interactor HHR
    80. NM_001375748.1 → NP_001362677.1  abl interactor 2 isoform zzz

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:309 → 369
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 89
      Abi_HHR; Abl-interactor HHR
    81. NM_001375749.1 → NP_001362678.1  abl interactor 2 isoform aaaa

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (1) summary
      cd11972
      Location:306 → 366
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    82. NM_001375750.1 → NP_001362679.1  abl interactor 2 isoform bbbb

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (3) summary
      cd11972
      Location:303 → 363
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:147 → 274
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:19 → 95
      Abi_HHR; Abl-interactor HHR
    83. NM_001375751.1 → NP_001362680.1  abl interactor 2 isoform cccc

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:290 → 350
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:19 → 82
      Abi_HHR; Abl-interactor HHR
    84. NM_001375752.1 → NP_001362681.1  abl interactor 2 isoform dddd

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:280 → 340
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:39 → 100
      Abi_HHR; Abl-interactor HHR
    85. NM_001375753.1 → NP_001362682.1  abl interactor 2 isoform eeee

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      pfam07815
      Location:19 → 89
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:262 → 296
      SH3; Src Homology 3 domain superfamily
    86. NM_001375754.1 → NP_001362683.1  abl interactor 2 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variant 4, encodes isoform d.
      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      cd11972
      Location:340 → 400
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:48 → 118
      Abi_HHR; Abl-interactor HHR
    87. NM_001375755.1 → NP_001362684.1  abl interactor 2 isoform qqq

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Conserved Domains (2) summary
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
      cl17036
      Location:336 → 370
      SH3; Src Homology 3 domain superfamily
    88. NM_005759.7 → NP_005750.4  abl interactor 2 isoform c

      See identical proteins and their annotated locations for NP_005750.4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in both the 5' and central coding regions, but includes an additional in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a.
      Source sequence(s)
      AC018891, AC080075
      Consensus CDS
      CCDS2358.1
      UniProtKB/TrEMBL
      E7EW77
      Related
      ENSP00000261017.5, ENST00000261017.9
      Conserved Domains (2) summary
      cd11972
      Location:414 → 474
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR

    RNA

    1. NR_164704.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    2. NR_164705.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    3. NR_164706.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    4. NR_164707.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    5. NR_164708.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    6. NR_164709.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    7. NR_164710.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    8. NR_164711.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    9. NR_164712.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    10. NR_164713.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
      Related
      ENST00000261016.11
    11. NR_164714.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    12. NR_164715.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    13. NR_164716.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    14. NR_164717.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075
    15. NR_164718.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018891, AC080075

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      203328394..203432169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047442823.1 → XP_047298779.1  abl interactor 2 isoform X1

      UniProtKB/TrEMBL
      E7EP65
    2. XM_047442826.1 → XP_047298782.1  abl interactor 2 isoform X4

      UniProtKB/TrEMBL
      E7EP65
    3. XM_006712180.4 → XP_006712243.1  abl interactor 2 isoform X9

      See identical proteins and their annotated locations for XP_006712243.1

      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:420 → 480
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    4. XM_047442831.1 → XP_047298787.1  abl interactor 2 isoform X10

      UniProtKB/TrEMBL
      E7EW77
    5. XM_006712181.4 → XP_006712244.1  abl interactor 2 isoform X12

      See identical proteins and their annotated locations for XP_006712244.1

      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:391 → 451
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    6. XM_017003132.3 → XP_016858621.1  abl interactor 2 isoform X14

      UniProtKB/TrEMBL
      E7EW77
    7. XM_047442832.1 → XP_047298788.1  abl interactor 2 isoform X11

      UniProtKB/TrEMBL
      E7EW77
    8. XM_006712182.4 → XP_006712245.1  abl interactor 2 isoform X13

      See identical proteins and their annotated locations for XP_006712245.1

      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:390 → 450
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    9. XM_047442834.1 → XP_047298790.1  abl interactor 2 isoform X15

      UniProtKB/TrEMBL
      E7EW77
    10. XM_047442835.1 → XP_047298791.1  abl interactor 2 isoform X16

      UniProtKB/TrEMBL
      E7EW77
    11. XM_017003144.3 → XP_016858633.1  abl interactor 2 isoform X19

      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (2) summary
      cd11972
      Location:342 → 402
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      pfam07815
      Location:93 → 169
      Abi_HHR; Abl-interactor HHR
    12. XM_017003138.3 → XP_016858627.1  abl interactor 2 isoform X17

      UniProtKB/TrEMBL
      E7EW77
      Conserved Domains (3) summary
      cd11972
      Location:370 → 430
      SH3_Abi2; Src homology 3 domain of Abl Interactor 2
      PHA03247
      Location:219 → 304
      PHA03247; large tegument protein UL36; Provisional
      pfam07815
      Location:93 → 156
      Abi_HHR; Abl-interactor HHR
    13. XM_047442824.1 → XP_047298780.1  abl interactor 2 isoform X2

      UniProtKB/TrEMBL
      E7EP65
    14. XM_047442827.1 → XP_047298783.1  abl interactor 2 isoform X5

      UniProtKB/TrEMBL
      E7EP65
    15. XM_047442825.1 → XP_047298781.1  abl interactor 2 isoform X3

      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
    16. XM_047442828.1 → XP_047298784.1  abl interactor 2 isoform X6

      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
    17. XM_047442829.1 → XP_047298785.1  abl interactor 2 isoform X7

      UniProtKB/TrEMBL
      E7EP65
    18. XM_047442836.1 → XP_047298792.1  abl interactor 2 isoform X18

    19. XM_047442837.1 → XP_047298793.1  abl interactor 2 isoform X20

    20. XM_047442830.1 → XP_047298786.1  abl interactor 2 isoform X8

      UniProtKB/TrEMBL
      E7EP65

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      203810332..203914077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054340092.1 → XP_054196067.1  abl interactor 2 isoform X1

      UniProtKB/TrEMBL
      E7EP65
    2. XM_054340100.1 → XP_054196075.1  abl interactor 2 isoform X9

      UniProtKB/TrEMBL
      E7EW77
    3. XM_054340101.1 → XP_054196076.1  abl interactor 2 isoform X10

      UniProtKB/TrEMBL
      E7EW77
    4. XM_054340103.1 → XP_054196078.1  abl interactor 2 isoform X12

      UniProtKB/TrEMBL
      E7EW77
    5. XM_054340105.1 → XP_054196080.1  abl interactor 2 isoform X14

      UniProtKB/TrEMBL
      E7EW77
    6. XM_054340102.1 → XP_054196077.1  abl interactor 2 isoform X11

      UniProtKB/TrEMBL
      E7EW77
    7. XM_054340104.1 → XP_054196079.1  abl interactor 2 isoform X13

      UniProtKB/TrEMBL
      E7EW77
    8. XM_054340106.1 → XP_054196081.1  abl interactor 2 isoform X15

      UniProtKB/TrEMBL
      E7EW77
    9. XM_054340107.1 → XP_054196082.1  abl interactor 2 isoform X16

      UniProtKB/TrEMBL
      E7EW77
    10. XM_054340110.1 → XP_054196085.1  abl interactor 2 isoform X19

      UniProtKB/TrEMBL
      E7EW77
    11. XM_054340108.1 → XP_054196083.1  abl interactor 2 isoform X17

      UniProtKB/TrEMBL
      E7EW77
    12. XM_054340093.1 → XP_054196068.1  abl interactor 2 isoform X2

      UniProtKB/TrEMBL
      E7EP65
    13. XM_054340095.1 → XP_054196070.1  abl interactor 2 isoform X21

      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
    14. XM_054340096.1 → XP_054196071.1  abl interactor 2 isoform X22

      UniProtKB/TrEMBL
      E7EP65
    15. XM_054340097.1 → XP_054196072.1  abl interactor 2 isoform X5

      UniProtKB/TrEMBL
      E7EP65
    16. XM_054340094.1 → XP_054196069.1  abl interactor 2 isoform X3

      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
    17. XM_054340098.1 → XP_054196073.1  abl interactor 2 isoform X6

      UniProtKB/Swiss-Prot
      B4DSN1, Q13147, Q13249, Q13801, Q9BV70, Q9NYB9
    18. XM_054340099.1 → XP_054196074.1  abl interactor 2 isoform X7

      UniProtKB/TrEMBL
      E7EP65
    19. XM_054340109.1 → XP_054196084.1  abl interactor 2 isoform X18

    20. XM_054340111.1 → XP_054196086.1  abl interactor 2 isoform X20

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