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    IFT54 Intraflagellar transport 54 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41739, updated on 9-Dec-2024

    Summary

    Official Symbol
    IFT54provided by FlyBase
    Official Full Name
    Intraflagellar transport 54provided by FlyBase
    Primary source
    FLYBASE:FBgn0038221
    Locus tag
    Dmel_CG3259
    See related
    AllianceGenome:FB:FBgn0038221
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3259; Dmel\CG3259; MIP-T3
    Summary
    Predicted to enable microtubule binding activity. Involved in cilium assembly. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in axoneme and ciliary basal body. Is expressed in chordotonal neurons; eo neurons; and larval antenno-maxillary sensory complex. Human ortholog(s) of this gene implicated in Senior-Loken syndrome. Orthologous to human TRAF3IP1 (TRAF3 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See IFT54 in Genome Data Viewer
    Location:
    88B3-88B3; 3-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14302428..14304458)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10128150..10130180)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45596 Neighboring gene red Malpighian tubules Neighboring gene suppressor of Hairy wing Neighboring gene RNA polymerase II subunit I Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables microtubule binding  
    enables molecular_function  
    Process Evidence Code Pubs
    involved_in cilium assembly  
    involved_in cilium assembly PubMed 
    involved_in cilium assembly PubMed 
    involved_in cilium assembly  
    involved_in intraciliary transport  
    involved_in regulation of microtubule cytoskeleton organization  
    Component Evidence Code Pubs
    is_active_in axoneme  
    is_active_in ciliary basal body  
    located_in cilium  
    part_of intraciliary transport particle  
    part_of intraciliary transport particle B  

    General protein information

    Preferred Names
    intraflagellar transport 54
    Names
    CG3259-PA
    IFT54-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14302428..14304458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142096.3 → NP_650353.1  intraflagellar transport 54 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650353.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFL0
      Related
      FBpp0082383
      Conserved Domains (1) summary
      pfam10243
      Location:53 → 588
      MIP-T3; Microtubule-binding protein MIP-T3
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