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    zfand2a zinc finger, AN1-type domain 2A [ Danio rerio (zebrafish) ]

    Gene ID: 393489, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zfand2aprovided by ZNC
    Official Full Name
    zinc finger, AN1-type domain 2Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1596
    See related
    Ensembl:ENSDARG00000103511 AllianceGenome:ZFIN:ZDB-GENE-040426-1596
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66295; zgc:77923
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein targeting to ER. Predicted to be active in endoplasmic reticulum. Orthologous to several human genes including ZFAND2B (zinc finger AN1-type containing 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See zfand2a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (43373932..43393253)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (42667819..42687238)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490738 Neighboring gene UNC homeobox Neighboring gene galanin receptor 2b Neighboring gene axin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC66295

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein targeting to ER IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    AN1-type zinc finger protein 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200517.2 → NP_956811.1  AN1-type zinc finger protein 2A

      See identical proteins and their annotated locations for NP_956811.1

      Status: PROVISIONAL

      Source sequence(s)
      BC065896
      UniProtKB/TrEMBL
      Q6NZZ5, Q7SXI4
      Related
      ENSDARP00000155855.1, ENSDART00000182497.1
      Conserved Domains (1) summary
      pfam01428
      Location:100 → 135
      zf-AN1; AN1-like Zinc finger

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      43373932..43393253
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005164202.5 → XP_005164259.1  AN1-type zinc finger protein 2A isoform X2

      UniProtKB/TrEMBL
      A0A8M2BBN9
      Conserved Domains (1) summary
      pfam01428
      Location:100 → 135
      zf-AN1; AN1-like Zinc finger

    2. XM_005164201.5 → XP_005164258.1  AN1-type zinc finger protein 2A isoform X1

      See identical proteins and their annotated locations for XP_005164258.1

      UniProtKB/TrEMBL
      Q6NZZ5, Q7SXI4
      Related
      ENSDARP00000139704.1, ENSDART00000159455.2
      Conserved Domains (1) summary
      pfam01428
      Location:100 → 135
      zf-AN1; AN1-like Zinc finger

    3. XM_021469821.2 → XP_021325496.1  AN1-type zinc finger protein 2A isoform X3

      UniProtKB/TrEMBL
      A0A8M9PT45
      Related
      ENSDART00000170444.2
      Conserved Domains (1) summary
      pfam01428
      Location:100 → 135
      zf-AN1; AN1-like Zinc finger

    4. XM_009299701.4 → XP_009297976.1  AN1-type zinc finger protein 2A isoform X4

      UniProtKB/TrEMBL
      A0A8M3B8H0
      Conserved Domains (1) summary
      pfam01428
      Location:100 → 135
      zf-AN1; AN1-like Zinc finger
    Nucleotide Protein Strain
    Heading Accession and Version

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