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    actc1b actin alpha cardiac muscle 1b [ Danio rerio (zebrafish) ]

    Gene ID: 58114, updated on 9-Dec-2024

    Summary

    Official Symbol
    actc1bprovided by ZNC
    Official Full Name
    actin alpha cardiac muscle 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000322-1
    See related
    Ensembl:ENSDARG00000099197 AllianceGenome:ZFIN:ZDB-GENE-000322-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    acta1; fa27h01; fb83f06; wu:fa27h01; wu:fb83f06
    Summary
    Predicted to be located in cytoskeleton. Predicted to be active in actin cytoskeleton. Is expressed in several structures, including EVL; mesoderm; musculature system; pericardial region; and trunk. Used to study nemaline myopathy. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See actc1b in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (117110..124665, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (117120..124675, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene gremlin 1b Neighboring gene Rho GTPase activating protein 11A Neighboring gene ryanodine receptor 3-like Neighboring gene kelch domain containing 2 Neighboring gene leucine rich repeat protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in actin cytoskeleton  
    located_in cytoskeleton  

    General protein information

    Preferred Names
    actin, alpha cardiac muscle 1b
    Names
    actin, alpha 1, skeletal muscle

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131591.1 → NP_571666.1  actin, alpha cardiac muscle 1b

      See identical proteins and their annotated locations for NP_571666.1

      Status: PROVISIONAL

      Source sequence(s)
      AF180887
      UniProtKB/TrEMBL
      A0A0R4I9K2, F6NGF7, Q9I8V1
      Related
      ENSDARP00000130083.1, ENSDART00000158825.3
      Conserved Domains (1) summary
      PTZ00281
      Location:4 → 377
      PTZ00281; actin; Provisional

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      117110..124665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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