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    trx-4 Thioredoxin [ Caenorhabditis elegans ]

    Gene ID: 189905, updated on 9-Dec-2024

    Summary

    Official Symbol
    trx-4
    Official Full Name
    Thioredoxin
    Primary source
    WormBase:WBGene00021548
    Locus tag
    CELE_Y44E3A.3
    See related
    AllianceGenome:WB:WBGene00021548
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein-disulfide reductase activity. Predicted to be active in cytoplasm. Is expressed in intestine and nervous system. Orthologous to human TXN (thioredoxin). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See trx-4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (3317978..3318584, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Carboxylic ester hydrolase Neighboring gene Uncharacterized protein Neighboring gene SH3 domain-containing protein Neighboring gene Creatinase_N domain-containing protein;Hydrolase;Uncharacterized protein Neighboring gene FHA domain-containing protein

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in cytoplasm  

    General protein information

    Preferred Names
    Thioredoxin
    NP_491142.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3317978..3318584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058741.4NP_491142.1  Thioredoxin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491142.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TXY8
      Conserved Domains (1) summary
      cd02947
      Location:9103
      TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...
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