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    Transducin/WD40 repeat-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831408, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Transducin/WD40 repeat-like superfamily protein
    Primary source
    TAIR:AT5G15550
    Locus tag
    AT5G15550
    See related
    Araport:AT5G15550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T20K14.160; T20K14_160
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    13
    Sequence:
    Chromosome: 5; NC_003076.8 (5058672..5062144, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene PHD finger family protein Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene Bromodomain transcription factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation and functional involvement of the Arabidopsis pescadillo ortholog AtPES in root development. Zografidis A, et al. Plant Sci, 2014 Dec. PMID 25443833
    2. Pescadillo plays an essential role in plant cell growth and survival by modulating ribosome biogenesis. Cho HK, et al. Plant J, 2013 Nov. PMID 23909681
    3. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
    4. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    5. Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions. Pendle AF, et al. Mol Biol Cell, 2005 Jan. PMID 15496452, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Pescadillo, BOP1, and WDR12 cofractionate with ribosome subunits.
      Title: Pescadillo plays an essential role in plant cell growth and survival by modulating ribosome biogenesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121559.3
    NM_203055.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    Transducin/WD40 repeat-like superfamily protein
    NP_197059.1
    • Transducin/WD40 repeat-like superfamily protein; FUNCTIONS IN: nucleotide binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleolus, CUL4 RING ubiquitin ligase complex, heterotrimeric G-protein complex; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), NLE (InterPro:IPR012972), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: WD-40 repeat family protein / notchless protein, putative (TAIR:AT5G52820.1); Has 33870 Blast hits to 20003 proteins in 673 species: Archae - 44; Bacteria - 4918; Metazoa - 12445; Fungi - 8096; Plants - 4252; Viruses - 0; Other Eukaryotes - 4115 (source: NCBI BLink).
    NP_974784.1
    • Transducin/WD40 repeat-like superfamily protein; FUNCTIONS IN: nucleotide binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleolus, CUL4 RING ubiquitin ligase complex, heterotrimeric G-protein complex; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), NLE (InterPro:IPR012972), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: WD-40 repeat family protein / small nuclear ribonucleoprotein Prp4p-related (TAIR:AT2G41500.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5058672..5062144 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343408.1 → NP_001332618.1  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LF27
      UniProtKB/TrEMBL
      A0A178UL95, A0A5S9Y535, A0A654G1Z1
      Conserved Domains (3) summary
      cd00200
      Location:109 → 426
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:154 → 203
      7WD40; WD40 repeat [structural motif]
      pfam08154
      Location:12 → 79
      NLE; NLE (NUC135) domain

    2. NM_121559.3 → NP_197059.1  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197059.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LF27
      UniProtKB/TrEMBL
      A0A178UL95, A0A5S9Y535, A0A654G1Z1
      Conserved Domains (3) summary
      cd00200
      Location:109 → 426
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:154 → 203
      7WD40; WD40 repeat [structural motif]
      pfam08154
      Location:12 → 79
      NLE; NLE (NUC135) domain

    3. NM_203055.1 → NP_974784.1  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974784.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G1Z1, F4KB59
      Conserved Domains (4) summary
      COG2319
      Location:109 → 390
      WD40; WD40 repeat [General function prediction only]
      pfam08154
      Location:12 → 79
      NLE; NLE (NUC135) domain
      sd00039
      Location:154 → 203
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:109 → 399
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LF27.1

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