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    DR4 drought-repressed 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843668, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DR4
    Official Full Name
    drought-repressed 4
    Primary source
    TAIR:AT1G73330
    Locus tag
    AT1G73330
    See related
    Araport:AT1G73330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATDR4; drought-repressed 4; T9L24.45; T9L24_45
    Summary
    encodes a plant-specific protease inhibitor-like protein whose transcript level in root disappears in response to progressive drought stress. The decrease in transcript level is independent from abscisic acid level.
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    Genomic context

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    See DR4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (27568714..27569823, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene Kunitz family trypsin and protease inhibitor protein Neighboring gene Cytochrome P450 superfamily protein Neighboring gene ankyrin repeat protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Abscisic acid-dependent and -independent regulation of gene expression by progressive drought in Arabidopsis thaliana. Gosti F, et al. Mol Gen Genet, 1995 Jan 6. PMID 7823904
    2. Profiling of the Receptor for Activated C Kinase 1a (RACK1a) interaction network in Arabidopsis thaliana. Guo J, et al. Biochem Biophys Res Commun, 2019 Dec 3. PMID 31606202
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105993.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peptidase inhibitor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of peptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    NOT involved_in response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    drought-repressed 4
    NP_177476.1
    • drought-repressed 4 (DR4); FUNCTIONS IN: peptidase inhibitor activity; INVOLVED IN: response to water deprivation; LOCATED IN: endomembrane system; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: LP.06 six leaves visible, LP.04 four leaves visible, 4 leaf senescence stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Proteinase inhibitor I3, Kunitz legume (InterPro:IPR002160), Kunitz inhibitor ST1-like (InterPro:IPR011065); BEST Arabidopsis thaliana protein match is: Kunitz family trypsin and protease inhibitor protein (TAIR:AT1G73325.1); Has 860 Blast hits to 860 proteins in 84 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 859; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27568714..27569823 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105993.3 → NP_177476.1  drought-repressed 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177476.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39091
      UniProtKB/TrEMBL
      A0A5S9WTZ7, A0A654ENJ5
      Conserved Domains (1) summary
      smart00452
      Location:28 → 192
      STI; Soybean trypsin inhibitor (Kunitz) family of protease inhibitors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39091.1

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