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    OVA2 tRNA synthetase class I (I, L, M and V) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834962, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OVA2
    Official Full Name
    tRNA synthetase class I (I, L, M and V) family protein
    Primary source
    TAIR:AT5G49030
    Locus tag
    AT5G49030
    See related
    Araport:AT5G49030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K19E20.18; K19E20_18; ovule abortion 2
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    Genomic context

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    See OVA2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    23
    Sequence:
    Chromosome: 5; NC_003076.8 (19874925..19883297, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene DNA replication protein-like protein Neighboring gene uncharacterized protein Neighboring gene protein arginine methyltransferase 4A Neighboring gene Disease resistance-responsive (dirigent-like protein) family protein Neighboring gene universal stress A-like protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Requirement of aminoacyl-tRNA synthetases for gametogenesis and embryo development in Arabidopsis. Berg M, et al. Plant J, 2005 Dec. PMID 16297076
    2. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036965.2
    NM_001203568.1
    NM_124280.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isoleucine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in isoleucyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within plant ovule development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 

    General protein information

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    Preferred Names
    tRNA synthetase class I (I, L, M and V) family protein
    NP_001032042.1
    • ovule abortion 2 (OVA2); FUNCTIONS IN: isoleucine-tRNA ligase activity, nucleotide binding, zinc ion binding, aminoacyl-tRNA ligase activity, ATP binding; INVOLVED IN: tRNA aminoacylation for protein translation, ovule development; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Isoleucyl-tRNA synthetase (InterPro:IPR018353), Isoleucyl-tRNA synthetase, class Ia (InterPro:IPR002301), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080), Isoleucyl-tRNA synthetase, class Ia, N-terminal (InterPro:IPR015905), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing (InterPro:IPR009008), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR013155), Aminoacyl-tRNA synthetase, class Ia (InterPro:IPR002300); BEST Arabidopsis thaliana protein match is: tRNA synthetase class I (I, L, M and V) family protein (TAIR:AT4G10320.1); Has 43537 Blast hits to 37490 proteins in 3160 species: Archae - 1106; Bacteria - 24914; Metazoa - 887; Fungi - 735; Plants - 377; Viruses - 0; Other Eukaryotes - 15518 (source: NCBI BLink).
    NP_001190497.1
    • ovule abortion 2 (OVA2); FUNCTIONS IN: in 6 functions; INVOLVED IN: tRNA aminoacylation for protein translation, ovule development; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Plant disease resistance response protein (InterPro:IPR004265), Isoleucyl-tRNA synthetase (InterPro:IPR018353), Isoleucyl-tRNA synthetase, class Ia (InterPro:IPR002301), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080), Isoleucyl-tRNA synthetase, class Ia, N-terminal (InterPro:IPR015905), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), DNA glycosylase/AP lyase/isoleucyl tRNA synthetase, zinc finger domain (InterPro:IPR010663), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR013155), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing (InterPro:IPR009008), Aminoacyl-tRNA synthetase, class Ia (InterPro:IPR002300); BEST Arabidopsis thaliana protein match is: Disease resistance-responsive (dirigent-like protein) family protein (TAIR:AT5G49040.1).
    NP_199714.2
    • ovule abortion 2 (OVA2); FUNCTIONS IN: in 6 functions; INVOLVED IN: tRNA aminoacylation for protein translation, ovule development; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Isoleucyl-tRNA synthetase (InterPro:IPR018353), Isoleucyl-tRNA synthetase, class Ia (InterPro:IPR002301), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080), Isoleucyl-tRNA synthetase, class Ia, N-terminal (InterPro:IPR015905), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), DNA glycosylase/AP lyase/isoleucyl tRNA synthetase, zinc finger domain (InterPro:IPR010663), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing (InterPro:IPR009008), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR013155), Aminoacyl-tRNA synthetase, class Ia (InterPro:IPR002300); BEST Arabidopsis thaliana protein match is: tRNA synthetase class I (I, L, M and V) family protein (TAIR:AT4G10320.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19874925..19883297 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124280.4 → NP_199714.2  tRNA synthetase class I (I, L, M and V) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199714.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DF95, F4K4Q4, Q8RXK8, Q9FI67
      UniProtKB/TrEMBL
      A0A5S9YCV5
      Conserved Domains (6) summary
      cd07960
      Location:770 → 956
      Anticodon_Ia_Ile_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases
      cd00818
      Location:533 → 770
      IleRS_core; catalytic core domain of isoleucyl-tRNA synthetases
      PLN02843
      Location:115 → 1089
      PLN02843; isoleucyl-tRNA synthetase
      pfam06827
      Location:1047 → 1073
      zf-FPG_IleRS; Zinc finger found in FPG and IleRS
      pfam13603
      Location:427 → 508
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
      cl00015
      Location:147 → 285
      nt_trans; nucleotidyl transferase superfamily

    2. NM_001203568.1 → NP_001190497.1  tRNA synthetase class I (I, L, M and V) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190497.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YCV5, F4K4Q2
      Conserved Domains (7) summary
      cd07960
      Location:956 → 1142
      Anticodon_Ia_Ile_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases
      cd00818
      Location:719 → 956
      IleRS_core; catalytic core domain of isoleucyl-tRNA synthetases
      PLN02843
      Location:301 → 1275
      PLN02843; isoleucyl-tRNA synthetase
      pfam03018
      Location:45 → 177
      Dirigent; Dirigent-like protein
      pfam06827
      Location:1233 → 1259
      zf-FPG_IleRS; Zinc finger found in FPG and IleRS
      pfam13603
      Location:613 → 694
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
      cl00015
      Location:333 → 471
      nt_trans; nucleotidyl transferase superfamily

    3. NM_001036965.2 → NP_001032042.1  tRNA synthetase class I (I, L, M and V) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032042.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YCV5
      Conserved Domains (5) summary
      cd07960
      Location:770 → 951
      Anticodon_Ia_Ile_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases
      cd00818
      Location:533 → 770
      IleRS_core; catalytic core domain of isoleucyl-tRNA synthetases
      TIGR00392
      Location:112 → 937
      ileS; isoleucyl-tRNA synthetase
      pfam13603
      Location:427 → 508
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
      cl00015
      Location:147 → 285
      nt_trans; nucleotidyl transferase superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RXK8.1

    Gene LinkOut

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