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    MYB96 myb domain protein 96 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836367, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MYB96
    Official Full Name
    myb domain protein 96
    Primary source
    TAIR:AT5G62470
    Locus tag
    AT5G62470
    See related
    Araport:AT5G62470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMYB96; K19B1.8; K19B1_8; myb domain protein 96; MYB DOMAIN PROTEIN 96; MYBCOV1
    Summary
    Encodes a R2R3 type Myb transcription factor whose expression is strongly induced by abscisic acid. Mediates abscisic acid signaling during drought stress response.
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    Genomic context

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    See MYB96 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (25078991..25081141, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene EMB514 (DUF3223) Neighboring gene RING/FYVE/PHD zinc finger superfamily protein Neighboring gene ncRNA Neighboring gene glutathione S-transferase tau 9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The MYB96 transcription factor mediates abscisic acid signaling during drought stress response in Arabidopsis. Seo PJ, et al. Plant Physiol, 2009 Sep. PMID 19625633, Free PMC Article
    2. MYB96-mediated abscisic acid signals induce pathogen resistance response by promoting salicylic acid biosynthesis in Arabidopsis. Seo PJ, et al. New Phytol, 2010 Apr. PMID 20149112
    3. The MYB96 transcription factor regulates cuticular wax biosynthesis under drought conditions in Arabidopsis. Seo PJ, et al. Plant Cell, 2011 Mar. PMID 21398568, Free PMC Article
    4. MYB96 shapes the circadian gating of ABA signaling in Arabidopsis. Lee HG, et al. Sci Rep, 2016 Jan 4. PMID 26725725, Free PMC Article
    5. Coordination of seed dormancy and germination processes by MYB96. Lee K, et al. Plant Signal Behav, 2015. PMID 26313409, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MYB94 and MYB96 additively inhibit callus formation via directly repressing LBD29 expression in Arabidopsis thaliana.
      Title: MYB94 and MYB96 additively inhibit callus formation via directly repressing LBD29 expression in Arabidopsis thaliana.
    2. MYB96 interacts with the histone modifier HDA15 to suppress negative regulators of early abscisic acid signaling
      Title: MYB96 recruits the HDA15 protein to suppress negative regulators of ABA signaling in Arabidopsis.
    3. MYB96 is a crucial regulator of triacylglycerol accumulation during seed maturation, which transcriptionally activates DGAT1 and PDAT1. The MYB96 gene is highly expressed in developing seeds and positively regulates triacylglycerol biosynthesis in seeds.
      Title: The MYB96 Transcription Factor Regulates Triacylglycerol Accumulation by Activating DGAT1 and PDAT1 Expression in Arabidopsis Seeds.
    4. This study showed that ABA regulates the expression of MYB30-responsive genes during pathogen infection and this regulation is partly dependent on MIEL1.
      Title: The Arabidopsis MIEL1 E3 ligase negatively regulates ABA signalling by promoting protein turnover of MYB96.
    5. MYB30-INTERACTING E3 LIGASE 1 (MIEL1) E3 ubiquitin ligase controls the protein stability of the two MYB transcription factors, MYB96 and MYB30, and thereby wax biosynthesis in Arabidopsis. These observations indicate that the MIEL1-MYB96 module is important for balanced cuticular wax biosynthesis in developing inflorescence stems.
      Title: The MIEL1 E3 Ubiquitin Ligase Negatively Regulates Cuticular Wax Biosynthesis in Arabidopsis Stems.
    6. The data collectively indicate that MYB94 and MYB96 exert an additive effect on cuticular wax biosynthesis, which may represent an efficient adaptive mechanism of response to drought in plants.
      Title: MYB94 and MYB96 Additively Activate Cuticular Wax Biosynthesis in Arabidopsis.
    7. MYB96 regulates abscisic acid gated induction of TOC1.
      Title: MYB96 shapes the circadian gating of ABA signaling in Arabidopsis.
    8. MYB96 is induced by cold stress in an abscisic acid -independent manner and subsequently activates freezing tolerance.
      Title: The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    9. MYB96 integrates a multitude of environmental stress signals and acts as a master regulator in the determination of timing for seed germination.
      Title: Coordination of seed dormancy and germination processes by MYB96.
    10. MYB96-ABI4 module regulates lipid mobilization specifically in the embryo to ensure proper seed germination under suboptimal conditions.
      Title: The Arabidopsis MYB96 Transcription Factor Is a Positive Regulator of ABSCISIC ACID-INSENSITIVE4 in the Control of Seed Germination.
    Submit: New GeneRIF Correction See all GeneRIFs (16)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125641.4
    NM_180917.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of abscisic acid-activated signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of wax biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of abscisic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of seed dormancy process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within wax biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    myb domain protein 96
    NP_201053.2
    • myb domain protein 96 (MYB96); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 94 (TAIR:AT3G47600.1); Has 9691 Blast hits to 8398 proteins in 583 species: Archae - 0; Bacteria - 56; Metazoa - 899; Fungi - 554; Plants - 5844; Viruses - 4; Other Eukaryotes - 2334 (source: NCBI BLink).
    NP_851248.1
    • myb domain protein 96 (MYB96); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 94 (TAIR:AT3G47600.1); Has 9954 Blast hits to 8500 proteins in 570 species: Archae - 0; Bacteria - 56; Metazoa - 1034; Fungi - 580; Plants - 5890; Viruses - 6; Other Eukaryotes - 2388 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25078991..25081141 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125641.4 → NP_201053.2  myb domain protein 96 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201053.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24JK1, Q6R036, Q9SPG0, Q9ZRY6
      UniProtKB/TrEMBL
      A0A178UF54, A0A5S9YIL4, A0A654GDC6
      Conserved Domains (1) summary
      PLN03212
      Location:5 → 116
      PLN03212; Transcription repressor MYB5; Provisional

    2. NM_180917.1 → NP_851248.1  myb domain protein 96 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851248.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UF54
      Conserved Domains (2) summary
      smart00717
      Location:14 → 62
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam00249
      Location:14 → 60
      Myb_DNA-binding; Myb-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q24JK1.1

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