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    F53B2.5 Importin subunit alpha [ Caenorhabditis elegans ]

    Gene ID: 178204, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F53B2.5
    Official Full Name
    Importin subunit alpha
    Primary source
    WormBase:WBGene00009956
    Locus tag
    CELE_F53B2.5
    See related
    AllianceGenome:WB:WBGene00009956
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F53B2.5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (12528529..12531147, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Protein eak-4 Neighboring gene Coiled-coil domain-containing protein 86 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in NLS-bearing protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Importin subunit alpha
    NP_502400.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12528529..12531147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069999.5 → NP_502400.2  Importin subunit alpha [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502400.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20703
      Conserved Domains (2) summary
      COG5064
      Location:87 → 397
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:69 → 97
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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