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    robl roadblock [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36963, updated on 9-Dec-2024

    Summary

    Official Symbol
    roblprovided by FlyBase
    Official Full Name
    roadblockprovided by FlyBase
    Primary source
    FLYBASE:FBgn0024196
    Locus tag
    Dmel_CG10751
    See related
    AllianceGenome:FB:FBgn0024196
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10751; DLC; Dmel\CG10751; l(2)k10408; LC7; Roadblock; roblk
    Summary
    Enables dynein intermediate chain binding activity. Involved in dendrite morphogenesis; microtubule-based movement; and mushroom body development. Part of axonemal dynein complex and cytoplasmic dynein complex. Orthologous to several human genes including DYNLRB2 (dynein light chain roadblock-type 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See robl in Genome Data Viewer
    Location:
    54B16-54B16; 2-82 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17456472..17457129)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13343977..13344634)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene roadblock similar 54B Neighboring gene uncharacterized protein Neighboring gene Testin

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    part_of axonemal dynein complex PubMed 
    is_active_in centrosome  
    is_active_in cytoplasm  
    part_of cytoplasmic dynein complex  
    part_of cytoplasmic dynein complex  
    part_of cytoplasmic dynein complex PubMed 

    General protein information

    Preferred Names
    roadblock
    Names
    CG10751-PA
    dynein light chain
    dynein light chain LC7
    dynein, light chain, roadblock-type 2
    robl-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17456472..17457129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079047.4 → NP_523771.1  roadblock [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523771.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KMS3
      Related
      FBpp0086076
      Conserved Domains (1) summary
      pfam03259
      Location:4 → 94
      Robl_LC7; Roadblock/LC7 domain
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