U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    CG12746 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40672, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG12746provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037341
    Locus tag
    Dmel_CG12746
    See related
    AllianceGenome:FB:FBgn0037341
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12746; WUN-like
    Summary
    Predicted to enable diacylglycerol diphosphate phosphatase activity and phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation and phospholipid metabolic process. Predicted to be active in membrane. Is expressed in several structures, including adult head; embryonic large intestine; embryonic/larval posterior spiracle; and gut section. Orthologous to human PLPP4 (phospholipid phosphatase 4) and PLPP5 (phospholipid phosphatase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CG12746 in Genome Data Viewer
    Location:
    83B2-83B2; 3-47.5 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5564865..5567435)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1390587..1393157)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol 4-kinase II alpha Neighboring gene antisense RNA:CR46136 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ras homolog enriched in brain

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables diacylglycerol diphosphate phosphatase activity  
    enables phosphatidate phosphatase activity  
    enables phosphatidate phosphatase activity  
    Process Evidence Code Pubs
    involved_in phospholipid dephosphorylation  
    involved_in phospholipid metabolic process  
    involved_in phospholipid metabolic process  
    involved_in phospholipid metabolic process  
    Component Evidence Code Pubs
    is_active_in membrane  
    located_in membrane  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG12746-PB
    CG12746-PD
    CG12746-PE
    PPAPDC1
    NP_649551.4
    NP_730949.2
    NP_788583.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5564865..5567435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176406.4 → NP_788583.1  uncharacterized protein Dmel_CG12746, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788583.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGV3, Q8IPQ4
      Related
      FBpp0078341
      Conserved Domains (1) summary
      cd03390
      Location:104 → 302
      PAP2_containing_1_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both ...
    2. NM_169067.5 → NP_730949.2  uncharacterized protein Dmel_CG12746, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730949.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGV3, Q8IPQ4
      Related
      FBpp0078338
      Conserved Domains (1) summary
      cd03390
      Location:104 → 302
      PAP2_containing_1_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both ...
    3. NM_141294.5 → NP_649551.4  uncharacterized protein Dmel_CG12746, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649551.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGV3, Q8IPQ4
      Conserved Domains (1) summary
      cd03390
      Location:104 → 302
      PAP2_containing_1_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both ...
    External link. Please review our privacy policy.