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    Obp22a Odorant-binding protein 22a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246672, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Obp22aprovided by FlyBase
    Official Full Name
    Odorant-binding protein 22aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0043539
    Locus tag
    Dmel_CG31941
    See related
    AllianceGenome:FB:FBgn0043539
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    22a; anon-AE003584.1; CG31941; DmelObp22a; Dmel\CG31941; Obp-b; obp22
    Summary
    Predicted to enable odorant binding activity. Involved in sexual reproduction. Located in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Obp22a in Genome Data Viewer
    Location:
    22B8-22B8; 2-3 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1991381..1992160, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1991381..1992160, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR42874 Neighboring gene Niemann-Pick type C-2a Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43464 Neighboring gene antisense RNA:CR45712 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster. Cridland JM, et al. Genetics, 2023 May 4. PMID 36869688, Free PMC Article
    2. Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis: a model of human neurodegenerative disease. Huang X, et al. Development, 2007 Oct. PMID 17804599
    3. Modulation of feeding behavior by odorant-binding proteins in Drosophila melanogaster. Swarup S, et al. Chem Senses, 2014 Feb. PMID 24302688, Free PMC Article
    4. The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster. Brown NC, et al. Elife, 2023 Dec 21. PMID 38126735, Free PMC Article
    5. Functional dissection of Odorant binding protein genes in Drosophila melanogaster. Swarup S, et al. Genes Brain Behav, 2011 Aug. PMID 21605338, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sexual reproduction HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular space HDA PubMed 

    General protein information

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    Preferred Names
    Odorant-binding protein 22a
    Names
    CG31941-PB
    CG31941-PC
    Obp22a-PB
    Obp22a-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1991381..1992160 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164447.3 → NP_722746.2  Odorant-binding protein 22a, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722746.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V3Q5, Q8IPY2, Q8MVX6
      Conserved Domains (1) summary
      cl11600
      Location:25 → 106
      PBP_GOBP; PBP/GOBP family

    2. NM_001014457.3 → NP_001014457.1  Odorant-binding protein 22a, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014457.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V3Q5, Q8IPY2, Q8MVX6
      Conserved Domains (1) summary
      cl11600
      Location:25 → 106
      PBP_GOBP; PBP/GOBP family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MVX6 Q8MVX6

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