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    CG7963 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41001, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7963provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037584
    Locus tag
    Dmel_CG7963
    See related
    AllianceGenome:FB:FBgn0037584
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7963
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7963 in Genome Data Viewer
    Location:
    84F15-84F15; 3-48 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8362826..8363894)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4188548..4189616)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Autophagy-related 13 Neighboring gene veneno Neighboring gene steamer duck Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46126 Neighboring gene Odorant-binding protein 85a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    2. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article
    3. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
    4. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860, Free PMC Article
    5. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Shokri L, et al. Cell Rep, 2019 Apr 16. PMID 30995488, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7963-PB
    NP_649798.3
    • complex mutation, may be evolving pseudogene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8362826..8363894
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141541.3 → NP_649798.3  uncharacterized protein Dmel_CG7963 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649798.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHR4
      Conserved Domains (4) summary
      COG5048
      Location:184 → 250
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:274 → 294
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:10 → 80
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:315 → 339
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHR4 Q9VHR4

    Gene LinkOut

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    Miscellaneous