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    npp-25 Transmembrane protein 33;Transmembrane protein 33 homolog [ Caenorhabditis elegans ]

    Gene ID: 189617, updated on 9-Dec-2024

    Summary

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    Official Symbol
    npp-25
    Official Full Name
    Transmembrane protein 33;Transmembrane protein 33 homolog
    Primary source
    WormBase:WBGene00012555
    Locus tag
    CELE_Y37D8A.17
    See related
    AllianceGenome:WB:WBGene00012555
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in endoplasmic reticulum tubular network organization and membrane organization. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in pharynx. Orthologous to human TMEM33 (transmembrane protein 33). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See npp-25 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (12920266..12925997, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene KHEYLRF-amide 4 Neighboring gene MARVEL domain-containing protein Neighboring gene Small ribosomal subunit protein uS10m Neighboring gene RRM domain-containing protein Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of Nuclear Pore Complexes in Caenorhabditis elegans by Live Imaging and Functional Genomics. de la Cruz Ruiz P, et al. Methods Mol Biol, 2022. PMID 35412238
    2. PP2A-B55(SUR-6) promotes nuclear envelope breakdown in C. elegans embryos. Kapoor S, et al. Cell Rep, 2023 Dec 26. PMID 37995185
    3. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
    4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum tubular network organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane protein 33;Transmembrane protein 33 homolog
    NP_001335544.1
    • Confirmed by transcript evidence
    NP_001335545.1
    • Confirmed by transcript evidence
    NP_001370967.1
    • Confirmed by transcript evidence
    NP_499684.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      12920266..12925997 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383016.1 → NP_001370967.1  Transmembrane protein 33 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1N7SYS5
      Conserved Domains (1) summary
      pfam03661
      Location:6 → 121
      UPF0121; Uncharacterized protein family (UPF0121)

    2. NM_067283.4 → NP_499684.1  Transmembrane protein 33 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499684.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XWV0
      Conserved Domains (1) summary
      pfam03661
      Location:40 → 269
      UPF0121; uncharacterized protein family (UPF0121)

    3. NM_001348641.3 → NP_001335544.1  Transmembrane protein 33 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1N7SYQ5
      Conserved Domains (1) summary
      pfam03661
      Location:1 → 223
      UPF0121; Uncharacterized protein family (UPF0121)

    4. NM_001348643.3 → NP_001335545.1  Transmembrane protein 33 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1N7SYR4
      Conserved Domains (1) summary
      pfam03661
      Location:1 → 141
      UPF0121; Uncharacterized protein family (UPF0121)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XWV0.1

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