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    lbh LBH regulator of WNT signaling pathway [ Danio rerio (zebrafish) ]

    Gene ID: 393492, updated on 9-Dec-2024

    Summary

    Official Symbol
    lbhprovided by ZNC
    Official Full Name
    LBH regulator of WNT signaling pathwayprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1613
    See related
    Ensembl:ENSDARG00000111701 AllianceGenome:ZFIN:ZDB-GENE-040426-1613
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66337
    Summary
    Acts upstream of or within embryonic viscerocranium morphogenesis and neural crest cell migration. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; digestive system; head; neural crest cell; and pleuroperitoneal region. Orthologous to human LBH (LBH regulator of WNT signaling pathway). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See lbh in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (51843154..51851143, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (51610559..51617621, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase 32C Neighboring gene inositol polyphosphate-5-phosphatase A Neighboring gene PWWP domain containing 2B Neighboring gene zmp:0000000755 Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene serum response factor b Neighboring gene kinesin light chain 1b Neighboring gene protein tyrosine kinase 7b Neighboring gene lysocardiolipin acyltransferase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC66337

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein LBH
    Names
    limb bud and heart development homolog-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200520.1NP_956814.1  protein LBH

      See identical proteins and their annotated locations for NP_956814.1

      Status: PROVISIONAL

      Source sequence(s)
      BC055606
      UniProtKB/TrEMBL
      Q7SXH0
      Related
      ENSDARP00000151597.1, ENSDART00000184663.1
      Conserved Domains (1) summary
      pfam15317
      Location:170
      Lbh; Cardiac transcription factor regulator, Developmental protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      51843154..51851143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)