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Conserved domains on  [gi|41055892|ref|NP_956814|]
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protein LBH [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Lbh super family cl21162
Cardiac transcription factor regulator, Developmental protein; The family of proteins are ...
 1-70 6.41e-24

Cardiac transcription factor regulator, Developmental protein; The family of proteins are cardiac transcription regulators, named Lbh, short for Limb, bud and heart. They regulate embryological development in the heart. More specifically, in humans, they may act as transcriptional activators in MAPK signaling pathway to mediate cellular functions. This family of proteins is found in eukaryotes. Proteins in this family are typically between 92 and 116 amino acids in length.


The actual alignment was detected with superfamily member pfam15317:

Pssm-ID: 434627  Cd Length: 101  Bit Score: 86.91  E-value: 6.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41055892     1 MTDVMISA----APMDDMRLSPSKE--RLTFQIFPDPSDFERCCKL-------KERLPSIVVEATE-GEVESGELRWPPE 66
Cdd:pfam15317   1 MALVPGNSedgpWPMDSPGSSQHPEspRLSNPLFKDRGEIDRVEKLqdiqvsqKTRLPSIVVEASEvGEEESGELRWPHE 80


                  ....
gi 41055892    67 DFLI 70
Cdd:pfam15317  81 ELLV 84
 
Name Accession Description Interval E-value
Lbh pfam15317
Cardiac transcription factor regulator, Developmental protein; The family of proteins are ...
 1-70 6.41e-24

Cardiac transcription factor regulator, Developmental protein; The family of proteins are cardiac transcription regulators, named Lbh, short for Limb, bud and heart. They regulate embryological development in the heart. More specifically, in humans, they may act as transcriptional activators in MAPK signaling pathway to mediate cellular functions. This family of proteins is found in eukaryotes. Proteins in this family are typically between 92 and 116 amino acids in length.


Pssm-ID: 434627  Cd Length: 101  Bit Score: 86.91  E-value: 6.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41055892     1 MTDVMISA----APMDDMRLSPSKE--RLTFQIFPDPSDFERCCKL-------KERLPSIVVEATE-GEVESGELRWPPE 66
Cdd:pfam15317   1 MALVPGNSedgpWPMDSPGSSQHPEspRLSNPLFKDRGEIDRVEKLqdiqvsqKTRLPSIVVEASEvGEEESGELRWPHE 80


                  ....
gi 41055892    67 DFLI 70
Cdd:pfam15317  81 ELLV 84
 
Name Accession Description Interval E-value
Lbh pfam15317
Cardiac transcription factor regulator, Developmental protein; The family of proteins are ...
 1-70 6.41e-24

Cardiac transcription factor regulator, Developmental protein; The family of proteins are cardiac transcription regulators, named Lbh, short for Limb, bud and heart. They regulate embryological development in the heart. More specifically, in humans, they may act as transcriptional activators in MAPK signaling pathway to mediate cellular functions. This family of proteins is found in eukaryotes. Proteins in this family are typically between 92 and 116 amino acids in length.


Pssm-ID: 434627  Cd Length: 101  Bit Score: 86.91  E-value: 6.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41055892     1 MTDVMISA----APMDDMRLSPSKE--RLTFQIFPDPSDFERCCKL-------KERLPSIVVEATE-GEVESGELRWPPE 66
Cdd:pfam15317   1 MALVPGNSedgpWPMDSPGSSQHPEspRLSNPLFKDRGEIDRVEKLqdiqvsqKTRLPSIVVEASEvGEEESGELRWPHE 80


                  ....
gi 41055892    67 DFLI 70
Cdd:pfam15317  81 ELLV 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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