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    ccdc125 coiled-coil domain containing 125 [ Danio rerio (zebrafish) ]

    Gene ID: 565477, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ccdc125provided by ZNC
    Official Full Name
    coiled-coil domain containing 125provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060526-104
    See related
    Ensembl:ENSDARG00000056477 AllianceGenome:ZFIN:ZDB-GENE-060526-104
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-214j8.8
    Summary
    Predicted to act upstream of or within regulation of cell motility. Predicted to be located in cytoplasm. Orthologous to human CCDC125 (coiled-coil domain containing 125). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ccdc125 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (26171564..26181863, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (25571411..25586981, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 34Bb Neighboring gene family with sequence similarity 151 member B Neighboring gene RAD17 checkpoint clamp loader component Neighboring gene zgc:86811

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in negative regulation of Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of cell motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of cell motility IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 125

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098182.1 → NP_001091652.1  coiled-coil domain-containing protein 125

      See identical proteins and their annotated locations for NP_001091652.1

      Status: PROVISIONAL

      Source sequence(s)
      BX510923
      UniProtKB/Swiss-Prot
      A2BGP7
      UniProtKB/TrEMBL
      A0A8M6Z6Y2, B3DJ72
      Related
      ENSDARP00000089271.3, ENSDART00000098500.5
      Conserved Domains (2) summary
      TIGR02168
      Location:55 → 221
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam09789
      Location:362 → 394
      DUF2353; Uncharacterized coiled-coil protein (DUF2353)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      26171564..26181863 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2BGP7.1 GenPept UniProtKB/Swiss-Prot:A2BGP7

    Gene LinkOut

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