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    Mtnap1 mitochondrial nucleoid associated protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287798, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mtnap1provided by RGD
    Official Full Name
    mitochondrial nucleoid associated protein 1provided by RGD
    Primary source
    RGD:1359207
    See related
    EnsemblRapid:ENSRNOG00000024780 AllianceGenome:RGD:1359207
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cell population proliferation; mitochondrial DNA metabolic process; and positive regulation of mitochondrial DNA replication. Predicted to be located in mitochondrial nucleoid. Orthologous to human MTNAP1 (mitochondrial nucleoid associated protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 90.8), Thymus (RPKM 30.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mtnap1 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (99227522..99237838)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (98728661..98738693)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (102199837..102210769)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 39, member 11 Neighboring gene somatostatin receptor 2 Neighboring gene component of oligomeric golgi complex 1 Neighboring gene VCP nuclear cofactor family member 1 Neighboring gene cleavage and polyadenylation specific factor 4-like Neighboring gene CDC42 effector protein 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC95088, MGC95210, MGC116358

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in mitochondrial DNA metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of mitochondrial DNA replication ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial nucleoid ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein C17orf80 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001393908.1 → NP_001380837.1  uncharacterized protein C17orf80 homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6ADE6, A0A8I6AET6, Q66H31
      Related
      ENSRNOP00000029802.3, ENSRNOT00000037371.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      99227522..99237838
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268770.1 → XP_063124840.1  uncharacterized protein C17orf80 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8I6ABB9, A0A8I6ADE6

    2. XM_063268769.1 → XP_063124839.1  uncharacterized protein C17orf80 homolog isoform X2

      UniProtKB/TrEMBL
      A0A8I6ADE6
      Related
      ENSRNOP00000092301.2, ENSRNOT00000113243.2

    3. XM_063268772.1 → XP_063124842.1  uncharacterized protein C17orf80 homolog isoform X4

      UniProtKB/TrEMBL
      A0A8I6ADE6, A0A8I6AET6, Q66H31

    4. XM_063268774.1 → XP_063124844.1  uncharacterized protein C17orf80 homolog isoform X5

      UniProtKB/TrEMBL
      A0A8I6ADE6, A6HKG8
      Related
      ENSRNOP00000090985.2, ENSRNOT00000117525.2

    5. XM_063268768.1 → XP_063124838.1  uncharacterized protein C17orf80 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8I6ABB9, A0A8I6ADE6

    6. XM_008768330.4 → XP_008766552.1  uncharacterized protein C17orf80 homolog isoform X4

      See identical proteins and their annotated locations for XP_008766552.1

      UniProtKB/TrEMBL
      A0A8I6ADE6, A0A8I6AET6, Q66H31

    7. XM_063268771.1 → XP_063124841.1  uncharacterized protein C17orf80 homolog isoform X3

    8. XM_063268775.1 → XP_063124845.1  uncharacterized protein C17orf80 homolog isoform X5

      UniProtKB/TrEMBL
      A0A8I6ADE6, A6HKG8

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001005532.3: Suppressed sequence

      Description
      NM_001005532.3: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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