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    AGG2 G-protein gamma subunit 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825532, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AGG2
    Official Full Name
    G-protein gamma subunit 2
    Primary source
    TAIR:AT3G22942
    Locus tag
    AT3G22942
    See related
    Araport:AT3G22942
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtGG2; G-protein gamma subunit 2
    Summary
    heterotrimeric G-protein gamma subunit 2(AGG2)
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    Genomic context

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    See AGG2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (8134077..8136204)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene ADP-ribosylation factor C1 Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oligomerization of A. thaliana Heterotrimeric G Protein Subunits AGB1 and AGG2 In Vitro. Kaplan-Türköz B, et al. Protein J, 2020 Oct. PMID 32772216
    2. Signaling specificity provided by the Arabidopsis thaliana heterotrimeric G-protein γ subunits AGG1 and AGG2 is partially but not exclusively provided through transcriptional regulation. Thung L, et al. PLoS One, 2013. PMID 23520518, Free PMC Article
    3. Arabidopsis heterotrimeric G-protein regulates cell wall defense and resistance to necrotrophic fungi. Delgado-Cerezo M, et al. Mol Plant, 2012 Jan. PMID 21980142
    4. Ggamma1 + Ggamma2 not equal to Gbeta: heterotrimeric G protein Ggamma-deficient mutants do not recapitulate all phenotypes of Gbeta-deficient mutants. Trusov Y, et al. Plant Physiol, 2008 Jun. PMID 18441222, Free PMC Article
    5. Isolation of a novel G-protein gamma-subunit from Arabidopsis thaliana and its interaction with Gbeta. Mason MG, et al. Biochim Biophys Acta, 2001 Aug 30. PMID 11513956

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Oligomerization of A. thaliana Heterotrimeric G Protein Subunits AGB1 and AGG2 In Vitro.
      Title: Oligomerization of A. thaliana Heterotrimeric G Protein Subunits AGB1 and AGG2 In Vitro.
    2. The fact that AGG1 and AGG2 are functionally interchangeable in some pathways implies that, at least for those pathways, signaling specificity resides in the distinctive spatiotemporal expression patterns exhibited by each gamma subunit.
      Title: Signaling specificity provided by the Arabidopsis thaliana heterotrimeric G-protein γ subunits AGG1 and AGG2 is partially but not exclusively provided through transcriptional regulation.
    3. AGG1, AGG2 and AGB1 control the immune responses and the regulation of cell wall composition.
      Title: Arabidopsis heterotrimeric G-protein regulates cell wall defense and resistance to necrotrophic fungi.
    4. Posttranslational modification of AGG2 is required for plasma membrane targeting.
      Title: Dual lipid modification of Arabidopsis Ggamma-subunits is required for efficient plasma membrane targeting.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_180415.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within basipetal auxin transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within lateral root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein palmitoylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein prenylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of heterotrimeric G-protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G-protein gamma subunit 2
    NP_850746.1
    • G-protein gamma subunit 2 (AGG2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: basipetal auxin transport, seed germination, lateral root development; LOCATED IN: plasma membrane, heterotrimeric G-protein complex; EXPRESSED IN: hydathode, root cortex, root epidermis, differentiation zone, guard cell; BEST Arabidopsis thaliana protein match is: Ggamma-subunit 1 (TAIR:AT3G63420.2); Has 82 Blast hits to 82 proteins in 13 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 82; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8134077..8136204
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180415.3 → NP_850746.1  G-protein gamma subunit 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850746.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93V47
      UniProtKB/TrEMBL
      A0A178V974, A0A5S9XEX6
      Conserved Domains (1) summary
      cl00069
      Location:27 → 100
      GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93V47.1

    Gene LinkOut

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