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    aceK isocitrate dehydrogenase kinase/phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944797, updated on 3-Dec-2024

    Summary

    Official Symbol
    aceK
    Official Full Name
    isocitrate dehydrogenase kinase/phosphatase
    Primary source
    ECOCYC:EG10026
    Locus tag
    b4016
    See related
    ASAP:ABE-0013131
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4008
    Summary
    Context determines which enzyme name is used, the kinase or the phosphatase. [More information is available at EcoCyc: EG10026].
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    Genomic context

    Sequence:
    NC_000913.3 (4218596..4220332)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene malate synthase A Neighboring gene isocitrate lyase Neighboring gene ncRNA Neighboring gene regulator of acetyl CoA synthetase Neighboring gene DNA-binding transcriptional repressor IclR Neighboring gene cobalamin-dependent methionine synthase

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables AMP binding  
    enables AMP binding PubMed 
    enables ATP binding  
    enables ATP binding PubMed 
    enables ATP binding  
    enables [isocitrate dehydrogenase (NADP+)] kinase activity  
    enables [isocitrate dehydrogenase (NADP+)] kinase activity PubMed 
    enables [isocitrate dehydrogenase (NADP+)] kinase activity  
    enables hydrolase activity, acting on ester bonds  
    enables magnesium ion binding PubMed 
    enables manganese ion binding PubMed 
    enables phosphatase activity  
    enables phosphoprotein phosphatase activity  
    enables phosphoprotein phosphatase activity  
    enables protein binding PubMed 
    enables protein serine/threonine kinase activity PubMed 
    enables protein serine/threonine kinase activity  
    enables protein serine/threonine phosphatase activity PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm PubMed 
    located_in cytoplasm  

    General protein information

    Preferred Names
    isocitrate dehydrogenase kinase/phosphatase
    NP_418440.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4218596..4220332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418440.1 isocitrate dehydrogenase kinase/phosphatase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418440.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FSU2, A0A3K1A8W6
      Conserved Domains (1) summary
      COG4579
      Location:1578
      AceK; Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]
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