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    Cdhr1 cadherin-related family member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 93662, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cdhr1provided by RGD
    Official Full Name
    cadherin-related family member 1provided by RGD
    Primary source
    RGD:620420
    See related
    EnsemblRapid:ENSRNOG00000013330 AllianceGenome:RGD:620420
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pcdh21
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion; photoreceptor cell morphogenesis; and photoreceptor cell outer segment organization. Predicted to act upstream of or within photoreceptor cell maintenance. Predicted to be located in photoreceptor outer segment membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 15. Orthologous to human CDHR1 (cadherin related family member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 91.7), Brain (RPKM 55.8) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Cdhr1 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (12863696..12883579, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (12843436..12863321, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (14328161..14348049, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene leucine-rich repeat, Ig-like and transmembrane domains 1 Neighboring gene leucine-rich repeat, Ig-like and transmembrane domains 2 Neighboring gene G protein-coupled receptor 15 ligand Neighboring gene cytochrome c, somatic pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • KIAA1775

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in photoreceptor cell maintenance IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within photoreceptor cell maintenance ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in photoreceptor cell maintenance ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in photoreceptor cell morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in photoreceptor cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in photoreceptor cell outer segment organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in photoreceptor cell outer segment organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in photoreceptor outer segment membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in photoreceptor outer segment membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cadherin-related family member 1
    Names
    MT-protocadherin
    photoreceptor cadherin
    prCAD
    protocadherin-21

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053572.2NP_446024.1  cadherin-related family member 1 precursor

      See identical proteins and their annotated locations for NP_446024.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/Swiss-Prot
      Q91XU7
      UniProtKB/TrEMBL
      A0A8L2Q9B0, A6K9J0
      Related
      ENSRNOP00000018631.6, ENSRNOT00000018630.7
      Conserved Domains (1) summary
      cd11304
      Location:139242
      Cadherin_repeat; Cadherin tandem repeat domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      12863696..12883579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)