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    CG11180 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37330, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11180provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034528
    Locus tag
    Dmel_CG11180
    See related
    AllianceGenome:FB:FBgn0034528
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11180
    Summary
    Predicted to enable telomerase inhibitor activity. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11180 in Genome Data Viewer
    Location:
    57A7-57A8; 2-91 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20620914..20623429, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16508419..16510934, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Heterogeneous nuclear ribonucleoprotein K Neighboring gene mir-7 stem loop Neighboring gene Hillarin Neighboring gene uncharacterized protein Neighboring gene Family with sequence similarity 21 Neighboring gene Reduction in Cnn dots 6 Neighboring gene uncharacterized protein Neighboring gene rigor mortis

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chigno/CG11180 and SUMO are Chinmo-interacting proteins with a role in Drosophila testes somatic support cells. Rinehart L, et al. PeerJ, 2024. PMID 38495765, Free PMC Article
    2. Identification of proteasome components required for apical localization of Chaoptin using functional genomics. Yano H, et al. J Neurogenet, 2012 Mar. PMID 22417167
    3. Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. Buffin E, et al. PLoS One, 2010 Feb 19. PMID 20174573, Free PMC Article
    4. Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Neumüller RA, et al. Cell Stem Cell, 2011 May 6. PMID 21549331, Free PMC Article
    5. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Vinayagam A, et al. Cell Rep, 2016 Sep 13. PMID 27626673, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Chigno/CG11180 and SUMO are Chinmo-interacting proteins with a role in Drosophila testes somatic support cells.
      Title: Chigno/CG11180 and SUMO are Chinmo-interacting proteins with a role in Drosophila testes somatic support cells.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables telomerase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11180-PA
    CG11180-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20620914..20623429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299709.1 → NP_001286638.1  uncharacterized protein Dmel_CG11180, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286638.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LG45
      Conserved Domains (1) summary
      pfam01585
      Location:27 → 70
      G-patch; G-patch domain

    2. NM_137651.2 → NP_611495.1  uncharacterized protein Dmel_CG11180, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611495.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBW6
      Related
      FBpp0085566
      Conserved Domains (1) summary
      pfam01585
      Location:27 → 70
      G-patch; G-patch domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LG45 A0A0B4LG45
    A1ZBW6 A1ZBW6
    Q8MSC9 Q8MSC9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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