NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|24656362|ref|NP_611495|]
View 

uncharacterized protein Dmel_CG11180, isoform A [Drosophila melanogaster]

Protein Classification

G patch domain-containing protein( domain architecture ID 10648273)

G patch domain-containing protein similar to Homo sapiens PIN2 (TERF1) interacting telomerase inhibitor 1, a microtubule-binding protein essential for faithful chromosome segregation

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 25-70 1.12e-08

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


:

Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 51.39  E-value: 1.12e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 24656362     25 DENRFGTKMLEKMGWTKGSGLGANLNGEKDFVRIRFKNDAEGLGFE 70
Cdd:smart00443   2 STSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGAV 47
 
Name Accession Description Interval E-value
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 25-70 1.12e-08

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 51.39  E-value: 1.12e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 24656362     25 DENRFGTKMLEKMGWTKGSGLGANLNGEKDFVRIRFKNDAEGLGFE 70
Cdd:smart00443   2 STSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGAV 47
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 27-68 1.67e-08

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 50.97  E-value: 1.67e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 24656362    27 NRFGTKMLEKMGWTKGSGLGANLNGEKDFVRIRFKNDAEGLG 68
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLG 43
 
Name Accession Description Interval E-value
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 25-70 1.12e-08

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 51.39  E-value: 1.12e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 24656362     25 DENRFGTKMLEKMGWTKGSGLGANLNGEKDFVRIRFKNDAEGLGFE 70
Cdd:smart00443   2 STSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGAV 47
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 27-68 1.67e-08

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 50.97  E-value: 1.67e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 24656362    27 NRFGTKMLEKMGWTKGSGLGANLNGEKDFVRIRFKNDAEGLG 68
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLG 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH