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    CG7888 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39232, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7888provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036116
    Locus tag
    Dmel_CG7888
    See related
    AllianceGenome:FB:FBgn0036116
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7888; SLC36
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be active in vacuolar membrane. Is expressed in adult abdomen; adult head; adult thorax; embryonic/larval salivary gland; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7888 in Genome Data Viewer
    Location:
    68A3-68A3; 3-34 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11054035..11059659)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11047135..11052759)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44547 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45119 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Biogenesis of lysosome-related organelles complex 1, subunit 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rapid metabolic shifts occur during the transition between hunger and satiety in Drosophila melanogaster. Wilinski D, et al. Nat Commun, 2019 Sep 6. PMID 31492856, Free PMC Article
    2. The Drosophila suppressor of underreplication protein binds to late-replicating regions of polytene chromosomes. Makunin IV, et al. Genetics, 2002 Mar. PMID 11901119, Free PMC Article
    3. miR-263a Regulates ENaC to Maintain Osmotic and Intestinal Stem Cell Homeostasis in Drosophila. Kim K, et al. Dev Cell, 2017 Jan 9. PMID 28017617, Free PMC Article
    4. Molecular Basis for Cephalic Mechanosensitivity of Drosophila Larvae. Zhang Z, et al. Neurosci Bull, 2020 Sep. PMID 32761438, Free PMC Article
    5. Metabolite transport across the mammalian and insect brain diffusion barriers. Weiler A, et al. Neurobiol Dis, 2017 Nov. PMID 28237316

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7888-PA
    CG7888-PB
    CG7888-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11054035..11059659
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168434.3 → NP_729652.1  uncharacterized protein Dmel_CG7888, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729652.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DME7, Q7YTZ0
      Related
      FBpp0075929
      Conserved Domains (2) summary
      COG0814
      Location:59 → 453
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:48 → 450
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. NM_168433.2 → NP_729651.1  uncharacterized protein Dmel_CG7888, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729651.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DME7, Q7YTZ0
      Related
      FBpp0075930
      Conserved Domains (2) summary
      COG0814
      Location:59 → 453
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:48 → 450
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. NM_140168.1 → NP_648425.1  uncharacterized protein Dmel_CG7888, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648425.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DME7, Q9VTD7, Q9VTD8
      Related
      FBpp0075931, FBtr0076201
      Conserved Domains (2) summary
      COG0814
      Location:62 → 456
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:51 → 453
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7YTZ0 Q7YTZ0
    Q9VTD7 Q9VTD7

    Gene LinkOut

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